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    Clinical outcomes of 3D printing individualized titanium mesh for severe alveolar bone defects: a retrospective series
    Xiong Zhenjie, Wei Yongxiang, Liu Qian, Chen Yaxin, Guo Xueqi, Ji Ruotong, Su Hanfu, Zou Yaokun, Wang Liping
    Chinese Journal of Oral Implantology    2025, 30 (1): 27-34.   DOI: 10.12337/zgkqzzxzz.2025.02.006
    Abstract1064)      PDF (1959KB)(385)       Save
    Objective To analyze the clinical outcomes and accuracy of 3D printing individualized titanium mesh (3D-PITM) in the treatment of severe alveolar bone defects. Methods This study involved 30 patients who underwent 3D-PITM supported guided bone regeneration (3D-PITMs GBR) at the Affiliated Stomatological Hospital of Guangzhou Medical University starting in February 2020. All patients signed informed consent and underwent surgery followed by regular postoperative follow-up. Individualized titanium meshes were fabricated using 3D printing technology, with preoperative virtual design and planning. Patients were followed for 6 to 8 months postoperatively, and clinical outcomes, as well as two-dimensional (2D) and three-dimensional (3D) imaging data, were collected and analyzed. Results Among the 30 patients, 4 experienced titanium mesh exposure, yielding an incidence rate of 13.33% (95% CI: 4.30%~22.36%). However, none of the patients experienced postoperative infections. During the 6-to 8-month follow-up period, implant sites achieved satisfactory bone augmentation in both horizontal and vertical dimensions. Imaging measurements revealed significant increases in alveolar bone width and height at 6 to 8 months postoperatively compared to preoperative values ( P<0.05). Postoperative bone augmentation volume also demonstrated significant improvement ( P<0.05). Furthermore, there were no statistically significant differences in alveolar bone changes between preoperative virtual planning and postoperative measurements (immediate and at 6 to 8 months) , indicating that 3D-PITM provides predictable bone augmentation outcomes. Conclusion 3D printing individualized titanium mesh effectively supports bone regeneration, achieves a high degree of matching with the defect site, and ensures the stability and effectiveness of newly formed bone. The 3D-PITM technique demonstrates high precision in restoring severe alveolar bone defects. Although complications such as titanium mesh exposure may occur, appropriate management can prevent the adverse impact on subsequent restoration outcomes. 3D-PITM is clinically valuable for restoring complex alveolar bone defects, providing reliable postoperative predictions and optimizing surgical planning.
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    Study on the osteogenic and antimicrobial properties of PEEK modified with a Ce-Ag-ZnO composite coating using PEI as a carrier
    Dai Yating, Han Zekui, Ru Xiaona, Lyu Yuguang, Li Bing, Gao Shijun
    Chinese Journal of Oral Implantology    2025, 30 (1): 54-61.   DOI: 10.12337/zgkqzzxzz.2025.02.010
    Abstract710)      PDF (2285KB)(312)       Save
    Objective This study aimed to utilize polyetherimide (PEI) as a carrier to coat a Ce-Ag-ZnO composite layer, enhancing the osteogenic and antibacterial properties of polyetheretherketone (PEEK). Methods Ce-Ag-ZnO composite powder was dissolved in a PEI solution and applied to PEEK via spin coating to form a uniform and stable coating. Three groups were established: the blank group (PEEK), the control group (PEEK+PEI), and the experimental group (PEEK+PEI+composite powder). The surface morphology, hydrophilicity, phase composition, element release, and coating adhesion were analyzed. The osteogenic potential of the samples was assessed using CCK-8, live/dead cell staining, cytoskeletal staining, ALP activity quantification, alizarin red staining, and quantitative reverse transcription PCR. The antibacterial efficacy was evaluated through bacterial colony counting. Results The Ce-Ag-ZnO composite powder was successfully coated onto the PEEK surface with a uniform distribution, allowing for controlled release. The experimental group exhibited significantly enhanced hydrophilicity ( P<0.001). On the 7th day, the experimental group showed superior MC3T3-E1 cell proliferation ( P<0.001), with well-spread pseudopodia and clear adhesion. Alizarin red staining demonstrated pronounced mineralization. The modified PEEK significantly upregulated ALP activity ( P<0.001) and the expression of osteogenic genes, including Runx2, BMP-2, OPN, and OCN ( P<0.001). The experimental group also exhibited the lowest bacterial adherence ( P<0.001). Conclusion The composite coating on the PEEK surface enhanced its biocompatibility, osteogenic potential, and antibacterial properties, thereby optimizing the surface performance of PEEK implants.
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    Research progress on metal-organic frameworks in dental medicine
    Li Jian, Liang Ye, Zhao Baodong
    Chinese Journal of Oral Implantology    2024, 29 (6): 602-609.   DOI: 10.12337/zgkqzzxzz.2024.12.025
    Abstract679)      PDF (1601KB)(1647)       Save
    Metal-organic frameworks (MOFs) are nanoporous materials synthesized through the self-assembly of metal nodes and organic ligands. They are characterized by their highly ordered porosity, tunable pore size, large specific surface area, and diverse structures. With the advancements and applications of MOFs in the biomedical field, an increasing number of researchers have introduced MOFs into dental medicine for research. New MOFs have been tailored or developed based on the characteristics of the oral environment and diseases for use in oral disease treatment. The most commonly used MOFs in dentistry primarily include zeolitic imidazolate framework-8 (ZIF-8) and zeolitic imidazolate framework-67 (ZIF-67). The structure and function of MOFs are suitable for treating oral diseases, and they have shown promising results in researches related to periodontal disease, oral and maxillofacial tumors, dental pulp disease, and dental implants. However, their effectiveness still requires further validation through clinical trials.
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    Innovations in minimally invasive techniques for external maxillary sinus floor elevation
    Zhu Liqin, Wang Huiming
    Chinese Journal of Oral Implantology    2024, 29 (6): 519-523.   DOI: 10.12337/zgkqzzxzz.2024.12.009
    Abstract604)      PDF (2179KB)(388)       Save
    The modified lateral window technique for sinus floor elevation using a mini-window is a minimally invasive approach derived from the traditional lateral window technique. This method reduces surgical trauma and enhances new bone formation in the maxillary sinus. Moreover, with the assistance of endoscopy, the surgical field in minimally invasive procedures can be improved, enabling timely detection and management of complications such as mucosal perforation. This article, drawing from evidence-based medicine and clinical cases, explains the mechanisms through which this modified technique promotes new bone formation in the maxillary sinus. It also highlights its clinical benefits, including reduced intraoperative and postoperative discomfort, such as pain, bleeding, and swelling. Furthermore, the article explores the methods and advantages of endoscopic assistance in sinus floor elevation.
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    Current status and prospects of lateral window technique for sinus floor elevation
    Gao Shaojingya, Cai Xiaoxiao
    Chinese Journal of Oral Implantology    2024, 29 (6): 549-554.   DOI: 10.12337/zgkqzzxzz.2024.12.014
    Abstract535)      PDF (1895KB)(426)       Save
    This study provides a comprehensive review of the development, technological advancements, and both the current and future trends of the lateral window technique for sinus floor elevation in clinical applications. lateral window technique for sinus floor elevation is a surgical procedure performed in cases of insufficient alveolar bone height in the posterior maxillary region by elevating the Schneiderian membrane via a lateral window and filling it with bone substitute materials to support dental implants. Although this technique provides excellent surgical visibility and operational flexibility, it is associated with considerable trauma and potential complications. Advances in minimally invasive techniques and the application of digital technologies have significantly improved the precision and safety of lateral window technique for sinus floor elevation procedures. This study also discusses the challenges and solutions for simultaneous implantation in cases of low residual bone height. Finally, the article points out that despite the obvious advantages of the lateral window technique for sinus floor elevation, careful handling of technical details is required in practical operations to ensure high success rates and surgical safety. Future studies need more clinical data to further verify the impact of different technical parameters on surgical outcomes, in order to provide both scientific guidance and valuable reference for clinical practice.
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    Causes, prevention and treatment of titanium mesh exposure after 3D printing individualized titanium mesh supported guided bone regeneration
    Su Yucheng, Ren Bin
    Chinese Journal of Oral Implantology    2025, 30 (1): 5-12.   DOI: 10.12337/zgkqzzxzz.2025.02.003
    Abstract508)      PDF (1665KB)(707)       Save
    3D printing individualized titanium mesh serves as a space maintenance device, effectively creating and maintaining osteogenic space, reducing intraoperative time and the difficulty of surgery. It is a reliable bone augmentation solution for various types of alveolar ridge bone defects. However, during clinical application, postoperative titanium mesh exposure is the most common complication and requires clinicians' attention. This article elaborates on the causes, prevention, and treatment of postoperative titanium mesh exposure in guided bone regeneration supported by 3D-PITM, with the aim of providing clinical reference.
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    Comparison of clinical outcomes between immediate implantation and delayed implantation following alveolar ridge preservation for single-tooth loss in the aesthetic zone
    Ren Shuaiji, Du Jingbing
    Chinese Journal of Oral Implantology    2024, 29 (6): 561-567.   DOI: 10.12337/zgkqzzxzz.2024.12.016
    Abstract496)      PDF (1647KB)(312)       Save
    Objective To investigate the short-term clinical outcomes of immediate implantation and delayed implantation following alveolar ridge preservation for single-tooth loss in the aesthetic zone. Methods A total of 90 patients with single-tooth loss in the aesthetic zone requiring implant restoration were selected from January 2021 to September 2022 at the Implant Department of Zhengzhou Zhide Stomatology Hospital. Based on the use of alveolar ridge preservation and timing of implantation, the patients were divided into two groups: the immediate implantation group ( n=45) and the alveolar ridge preservation group ( n=45). The immediate implantation group underwent the immediate implant placement and restoration, while the alveolar ridge preservation group received delayed implantation after ridge preservation, followed by immediate restoration. Alveolar bone-related parameters, inflammatory markers[C-reactive protein (CRP) and tumor necrosis factor-alpha(TNF-α)], aesthetic outcomes[pink esthetic score (PES) and white esthetic score (WES)], and patient satisfaction were analyzed and compared between the two groups. Results After 6 months of implant restoration, both groups showed reductions in alveolar bone height, width, and density compared to baseline ( P<0.05); however, the immediate implantation group exhibited higher values than the alveolar ridge preservation group ( P<0.05). One month post-restoration, CRP and TNF-α levels increased in both groups compared to baseline ( P<0.05), but levels in the immediate implantation group were significantly lower than in the alveolar ridge preservation group ( P<0.05). After 6 months of permanent restoration, the immediate implantation group demonstrated superior outcomes in lip-side gingival contour, gingival height, soft tissue color, texture, and PES total scores compared to the alveolar ridge preservation group ( P<0.05). Similarly, crown profile, surface texture scores, and WES scores were higher in the immediate implantation group ( P<0.05). Patient satisfaction regarding gingival attachment height, aesthetics, and masticatory function was also higher in the immediate implantation group ( P<0.05). Conclusion Both immediate implantation and delayed implantation following alveolar ridge preservation are effective for treating single-tooth loss in the aesthetic zone. However, immediate implantation demonstrates greater advantages in improving alveolar bone quality, oral aesthetics, inflammation responses, and patient satisfaction.
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    Simultaneous management of maxillary sinus cysts during sinus floor elevation
    Bao Yuejie, Zhan Pingping, Lin Zhihao, He Gang
    Chinese Journal of Oral Implantology    2024, 29 (6): 543-548.   DOI: 10.12337/zgkqzzxzz.2024.12.013
    Abstract435)      PDF (2026KB)(809)       Save
    This article introduces a surgical approach for the simultaneous management of maxillary sinus cysts and sinus floor elevation using the double-window technique. The first lateral window is created to elevate the Schneiderian membrane and establish space for bone augmentation. Once the membrane is fully elevated and remains intact, a second small lateral window is created above the first to remove the cyst. The two windows are separated to prevent contamination of the graft material by the cystic contents. Additionally, a conservative surgical approach for the palliative treatment of sinus cysts is presented. Three representative cases are described to demonstrate specific techniques and surgical methods.
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    Application of digital guides in full-arch immediate implantation of patients with periodontitis
    Yang Aifen, Zhou Liwei
    Chinese Journal of Oral Implantology    2024, 29 (6): 585-589.   DOI: 10.12337/zgkqzzxzz.2024.12.022
    Abstract405)      PDF (1649KB)(384)       Save
    Implant-supported full-arch fixed restorations have become an important treatment for potentially edentulous jaws with severe periodontitis. The advent of immediate implantation has dramatically shortened the treatment period of patients, and digital guides allow for precise, efficient and minimally invasive immediate implant surgery. However, there are few clinical reports on full-arch immediate implantation using digital guides in patients with severe periodontitis. In this review, the application of different digital guides in full-arch immediate implant placement for patients with severe periodontitis is discussed and summarized.
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    Research progress and clinical application of dental implant macro-design
    Cai Wenyu, Ma Junchi, Zhao Wenbo, Wang Yiming, Zhou Libo
    Chinese Journal of Oral Implantology    2025, 30 (2): 180-186.   DOI: 10.12337/zgkqzzxzz.2025.04.013
    Abstract362)      PDF (1295KB)(672)       Save
    In recent years, the design of implant configurations has been continuously optimized, playing a key role in improving initial stability and promoting osseointegration, which are key factors for achieving long-term functional stability of implants. However, there is still no unified consensus on the optimal implant configuration. This article explores various aspects of implant design, including the neck structure, thread pattern, overall shape, apex features, diameter, and length, with different bone qualities and clinical conditions, such as immediate and delayed implantation, as well as anterior and posterior implantation sites. By summarizing the most favorable implant configurations identified in current research, this review aims to provide a reference for clinical applications.
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    A case report of a peri-implant cyst
    Xu Manjun, Liu Chunjie, Sun Licong, Li Hong, Guo Fujun
    Chinese Journal of Oral Implantology    2025, 30 (4): 384-387.   DOI: 10.12337/zgkqzzxzz.2025.08.009
    Abstract341)      PDF (1599KB)(252)       Save
    This paper reports a case of a peri-implant cyst associated with periapical periodontitis of the adjacent tooth. The patient presented with swelling and pain around the implant at site 47 in the right mandible, and the diagnosis was confirmed by cone beam computed tomography and other examinations. Treatment included removal of the loosened implant at site 47 and curettage of the cystic lesion. Additionally, a partial root resection and lesion curettage were performed on tooth 46. Histopathological examination confirmed an odontogenic cyst with secondary infection. Follow-up showed satisfactory wound healing without complications. Based on an in-depth analysis of this case and a review of the relevant literature, we comprehensively discuss the etiology, clinical features, diagnostic approaches, and prevention and treatment strategies for peri-implant cysts. This report aims to provide valuable insights for oral implant clinicians to enhance understanding, diagnosis, and management of this condition.
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    Comparison of bone augmentation effects between digital titanium mesh and resorbable collagen membrane: a retrospective study
    Li Songhang, Cai Xiaoxiao
    Chinese Journal of Oral Implantology    2025, 30 (1): 19-26.   DOI: 10.12337/zgkqzzxzz.2025.02.005
    Abstract334)      PDF (1736KB)(337)       Save
    Objective To evaluate the clinical outcomes of bone augmentation using digital titanium mesh versus absorbable collagen membrane. Methods From January 2019 to December 2020, 24 patients with Terheyden type 2/4 or 3/4 bone defects were treated at the Department of Oral Implantology, West China Hospital of Stomatology. These patients were divided into two groups: the absorbable collagen membrane group (12 cases) and digital titanium mesh group (12 cases). Both groups underwent guided bone regeneration with absorbable collagen membrane and digital titanium mesh as barrier membranes, respectively. The two-dimensional and three-dimensional measurements of alveolar bone were taken at four time points: pre-surgery (T 1), post- surgery (T 2), before second-stage surgery (T 3), and one year after loading (T 4), to evaluate hard tissue stability. Results Both the absorbable collagen membrane group and the digital titanium mesh group achieved excellent bone augmentation outcomes after surgery. The average single-tooth augmentation was 354.43 mm 3 (330.04, 403.93) in the absorbable membrane group, and in the digital titanium mesh group, it was 368.98 mm³ (320.90, 441.61). Although the labial bone in the absorbable collagen membrane group was thicker than in the digital titanium mesh group at T 2, after the healing and loading periods, the digital titanium mesh group exhibited thicker labial bone at all measurement points. Both in the short-term healing and long-term functional phases, the resorption of the labiolingual bone in the digital titanium mesh group was lower than in the absorbable collagen membrane group. Additionally, the digital titanium mesh group showed superior bone preservation results in terms of three-dimensional volume. Conclusion Digital titanium mesh offers superior bone augmentation effects compared to absorbable collagen membranes. It maintains a stable osteogenic space during the early healing phase and exerts a positive influence during the loading phase.
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    Clinical research progress on immediate implant placement in patients facing tooth loss due to periodontitis after periodontal initial therapy
    Lu Yifan, Luo Hongke, Chen Qianming, Si Misi
    Chinese Journal of Oral Implantology    2024, 29 (6): 574-579.   DOI: 10.12337/zgkqzzxzz.2024.12.018
    Abstract328)      PDF (1584KB)(414)       Save
    In clinical practice, implant-supported fixed prostheses are considered a reliable treatment option for patients with tooth loss. However, for patients facing tooth loss due to periodontitis, traditional approaches suggest that an implant plan should only be made after soft tissue healing to avoid the potential negative effects of residual inflammatory tissue from tooth extraction. With advancements in technology, immediate implant placement has gained increasing attention as a way to enhance treatment outcomes and shorten the treatment cycle, provided periodontal infection is well controlled. Several studies have already explored this approach. This article summarizes the literature and analyzes current research on immediate implant treatment in patients with tooth loss due to periodontitis following periodontal initial therapy. The relevant experiences are summarized to help standardize clinical practice.
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    Progress in pseudo-periosteum formation under titanium mesh assisted guided bone regeneration
    Yang Minxue, Li Dize, Chen Tao
    Chinese Journal of Oral Implantology    2025, 30 (1): 35-39.   DOI: 10.12337/zgkqzzxzz.2025.02.007
    Abstract325)      PDF (1429KB)(521)       Save
    In addressing complex bone defects, titanium mesh, as one of the non-absorbable barrier membranes, plays a key role in space maintenance. After surgery, a dense fibrous connective tissue, known as pseudo-periosteum, often forms on the surface of the newly formed bone. This tissue can be categorized into three types based on its thickness. The formation of the pseudo-periosteum is closely associated with the use of titanium mesh, and its formation remains unavoidable even with the use of 3D printing individualized titanium mesh. The factors influencing the formation of the pseudo-periosteum are not yet fully understood, but may be include variables such as micromotion of the titanium mesh and pore size. In clinical applications, the pseudo-periosteum has certain value in soft tissue augmentation and protection of new bone, but some researchers argue that it may occupy bone-forming space, and whether it should be retained remains controversial. Currently, the formation mechanism, anatomical and histological characteristics, clinical value, and retention controversies of the pseudo-periosteum have not been comprehensively and systematically elucidated. This review aims to provide a comprehensive analysis of the formation, histological characteristics, clinical applications, and retention controversies of the pseudo-periosteum under titanium mesh, with the goal of offering guidance and reference for clinical practice.
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    Static mechanical analysis of individualized titanium mesh for restoring extensive mandible alveolar bone defects
    Wang Huaisheng, Han Zekui, Zang Yixin, Song Zhenyu, Song Yihan, Sun Zihui, Wang Xinyu
    Chinese Journal of Oral Implantology    2025, 30 (1): 13-18.   DOI: 10.12337/zgkqzzxzz.2025.02.004
    Abstract294)      PDF (2724KB)(322)       Save
    Objective To investigate the biomechanical effects of varying retention pin numbers and positions on 3D printed individualized titanium mesh used for restoring extensive bone defects through finite element analysis. Methods A digital model of extensive bone defects in the mandible was constructed. Virtual bone augmentation was performed using 3-Matic 15 and Geomagic Wrap 2021 software, followed by the design of individualized titanium meshes. Five models with different retention pin numbers and positions were analyzed: (A) four retention pins (buccal mesial, buccal median, mandibular ramus, and lingual side); (B) three retention pins (buccal mesial, buccal median, mandibular ramus); (C) two retention pins (buccal mesial, buccal median); (D) two retention pins (buccal mesial, mandibular ramus); (E) two retention pins (buccal median, mandibular ramus). Finite element analysis models were constructed to evaluate the displacement and stress distribution of the titanium meshes in each group. Results Titanium mesh with four retention pins exhibited the smallest overall displacement (maximum: 0.088 mm), effectively protecting the internal bone graft material. The mesh with three retention pins showed relatively uniform displacement on the buccal side and alveolar ridge crest; however, the absence of lingual-side retention pins resulted in larger displacements, concentrated in the distal lingual area (maximum: 0.263 mm). In the three models with two retention pins, when the pins were located at the buccal mesial and median, the absence of retention pins in the distal regions led to increasing displacement as the distance from the pins increased, with a maximum displacement of 3.255 mm. In the model with retention pins at the buccal mesial and mandibular ramus, the long span of the titanium mesh caused downward deformation in the central section under load, with the deformation gradually decreasing toward both ends, while the free mesial end experienced upward buckling forces, resulting in a maximum displacement of 0.728 mm. In the model where the pins were located at the buccal median and mandibular ramus, the longer mesial cantilever beam led to significant deformation closer to the mesial end, with the maximum deformation reaching 3.823 mm. Titanium meshes with four retention pins and those with pins at the buccal mesial and median exhibited uniform stress distribution without notable stress concentrations. Meshes with three retention pins showed stress concentrations on the buccal side and around the retention pins. For meshes with pins located at the buccal mesial and mandibular ramus, or at the buccal median and mandibular ramus, stress was concentrated around the two pins. Maximum stresses for models A, B, C, D and E were 183.29, 451.30, 722.22, 904.84 and 1462.40 MPa, respectively. Conclusion Increasing the number of retention pins reduces the displacement of individualized titanium mesh under load. For the same number of retention pins, their positions significantly influence mesh displacement.
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    Autonomous dental implant robot (ADIR) combined with bone condensing drills used for transcrestal maxillary sinus elevation simultaneously implant placement: a case report
    Chen Na, Chen Tao, Huang Yuanding
    Chinese Journal of Oral Implantology    2025, 30 (1): 74-80.   DOI: 10.12337/zgkqzzxzz.2025.02.013
    Abstract284)      PDF (2106KB)(364)       Save
    A patient who underwent extraction of the upper left first molar due to crown-root fracture three months ago requested implant restoration. CBCT examination revealed insufficient residual alveolar bone height and low bone density at the edentulous site. In this case, an autonomous dental implant robot, combined with an bone condensing drilling kit, based on machine vision and a force servo control system, was used to simultaneously perform bone condensing, transalveolar maxillary sinus floor elevation, and implant placement under the precise guidance of the robotic arm. During surgery, there was no perforation of the maxillary sinus membrane, and the implant initial stability was excellent, with errors at the platform and apex less than 1mm and angular error less than 2°. There were no complications such as postoperative maxillary sinus infection. A follow-up CBCT examination six months after the operation showed good osseointegration of the implant, with a height increase of the maxillary sinus ranging from 3 to 5 mm, a volume increase of 291.47 mm³, and an IST value of 77. The second stage, including gingivoplasty, implant restorative impression, and final upper prosthetic restoration, was completed following standard procedures. This case presents a digital guidance method for implant surgery using an autonomous dental implant robot for sinus floor elevation, Bone condensing, and implant placement in cases of posterior maxillary tooth loss with low bone density and insufficient vertical bone volume.
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    A case report on dental implant surgery for a patient with severe gag reflex and multiple tooth loss
    Xu Xinghuanyu, Yang Yanlan, Xu Pu, Yu Dou, Lu Liying
    Chinese Journal of Oral Implantology    2025, 30 (1): 81-85.   DOI: 10.12337/zgkqzzxzz.2025.02.014
    Abstract276)      PDF (2441KB)(400)       Save
    This study aims to share the clinical experience of performing dental implantation in patients with severe gag reflex, providing a reference for the treatment of similar patients. The patient was maintained in a 45° sitting position, and medicated rinsing, local anesthesia, and nerve block anesthesia were used in combination to facilitate the procedure. A user-friendly implant system was employed during the surgery. The severe gag reflex was successfully suppressed, and the dental implant placements were completed smoothly. Postoperative CBCT confirmed proper placement of the implants, and follow-up visits showed satisfactory wound healing. For patients with severe gag reflex, medicated rinsing can effectively reduce discomfort and facilitate successful dental implantation.
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    The characteristics of nisin and its application in peri-implantitis: a review of recent research
    Wang Yu
    Chinese Journal of Oral Implantology    2025, 30 (1): 86-90.   DOI: 10.12337/zgkqzzxzz.2025.02.015
    Abstract276)      PDF (1723KB)(564)       Save
    Peri-implantitis is one of the main causes of implants failure. Nisin is a bacteriocin produced by Lactobacillus, which exerts bacteriostatic effects by forming pores in bacterial cell membranes. Nisin has been shown to effectively inhibit the pathogenic bacteria associated with peri-implantitis, demonstrating its potential for use in the treatment of this condition. This review article discusses the characteristics of nisin and the research progress on its application in peri-implantitis.
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    Causes, treatment, and prevention of mucoperiosteal perforation during lateral window technique for sinus floor elevation
    Su Yucheng, Ren Bin
    Chinese Journal of Oral Implantology    2024, 29 (6): 512-518.   DOI: 10.12337/zgkqzzxzz.2024.12.008
    Abstract263)      PDF (1851KB)(581)       Save
    Following maxillary posterior tooth loss, the residual bone height and width are often compromised due to maxillary sinus pneumatization and alveolar ridge resorption. The lateral window technique for sinus floor elevation is a common procedure to address vertical bone deficiencies in this region. Intraoperative mucoperiosteal perforation is the most frequent complication encountered, posing a challenge for every implant surgeon. This article reviews the diagnosis, causes, treatment strategies, and prevention of mucoperiosteal perforation during lateral window technique for sinus floor elevation, aiming to provide clinicians with practical insights for managing this complication.
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    Effect of acid pickling pretreatment on the microstructure and corrosion resistance of Ti-6Al-4V alloy
    Zhao Yujia, Liu Qiqi, Qiu Lin, Hao Junjiang, Su Hanqi, Han Zekui, Wang Xinyu, Su Yucheng
    Chinese Journal of Oral Implantology    2025, 30 (1): 47-53.   DOI: 10.12337/zgkqzzxzz.2025.02.009
    Abstract262)      PDF (1846KB)(362)       Save
    Objective To evaluate the changes in the microstructure and corrosion resistance of Ti-6Al-4V alloy after different acid pickling pretreatments and to determine the optimal pickling method for titanium alloys used as implantable biomaterials. Methods The microstructure, hydrophilic properties, and corrosion resistance of machined Ti-6Al-4V alloy samples pickled with HF+H 2SO 4, HF+HNO 3, and HF solutions were analyzed using contact angle measurements, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and electrochemical tests. Results 1. Pickling rates varied among the three solutions: HF+H 2SO 4 (0.088 μm/s), HF+HNO 3 (0.064 μm/s), and HF (0.097 μm/s). 2. All groups exhibited characteristic α+β phase microstructures, with a higher proportion of β phase observed in the HF+HNO 3 and HF groups compared to the HF+H 2SO 4 group. The HF group also displayed hydride phases. Optical microscopy revealed the least pitting corrosion in the HF+HNO 3 group. 3. Corrosion resistance testing in simulated body fluids showed the following order of self-corrosion potential: control group > HF+HNO 3 group > HF+H 2SO 4 group > HF group. Conclusion HF+HNO 3 pickling produced Ti-6Al-4V alloy samples with smooth surfaces, a contact angle of 47.63°±2.40°, a weight loss rate of 1.11%±0.08%, and uniform removal of organic impurities and oxide films. The C/Ti and O/Ti ratios were reduced to 0.047±0.001 and 0.040±0.008, respectively. This treatment achieved higher corrosion resistance, with a self-corrosion potential of -0.676V. HF+HNO 3 is recommended as the preferred pickling solution for producing implantable Ti-6Al-4V alloys with superior corrosion resistance and a clean, uniform surface.
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    The application of digital technology in the lateral window technique for sinus floor elevation
    Gao Jiayu, Man Yi
    Chinese Journal of Oral Implantology    2024, 29 (6): 537-542.   DOI: 10.12337/zgkqzzxzz.2024.12.012
    Abstract260)      PDF (2452KB)(335)       Save
    The loss of maxillary posterior teeth frequently leads to alveolar bone resorption and maxillary sinus pneumatization, resulting in a significant reduction in vertical bone height. The lateral window technique for sinus floor elevation involves creating a lateral window in the maxillary sinus and elevating the sinus membrane to achieve vertical bone augmentation in the posterior maxilla, thereby meeting the bone height requirements for implant placement. Digital technology has been widely applied to this procedure, effectively reducing surgical complications. This paper explores the application of digital technology-assisted LSFE in cases with oblique sinus floors, sinus septa, cysts, or foreign bodies, aiming to provide a reference for clinical practice.
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    Effect of different sandblasting parameters on the surface roughness of medical-grade Grade 4 pure titanium
    Liu Qiqi, Zhao Yujia, Qiu Lin, Hao Junjiang, Su Hanqi, Han Zekui, Wang Xinyu, Su Yucheng
    Chinese Journal of Oral Implantology    2024, 29 (6): 555-560.   DOI: 10.12337/zgkqzzxzz.2024.12.015
    Abstract259)      PDF (1786KB)(600)       Save
    Objective This study investigates the effect of different sandblasting parameters on the surface roughness of medical-grade Grade 4 pure titanium, aiming to provide reference data for optimizing SLA(sandblasted, large-grit, acid-etched) surface characteristics. Methods Alumina particles were used in an orthogonal experimental design to analyze the effects of particle size, pressure, distance, and time on the surface roughness average (Ra) of Grade 4 pure titanium. Range analysis and variance analysis were performed to evaluate the impact of each parameter. Results The surface roughness with Ra value of 1.083~2.494 μm can be obtained within the range of factor levels in this experiment. The lowest surface roughness (Group A) was achieved with 100-mesh particles, 0.2 MPa pressure, a distance of 50 mm, and a duration of 60 seconds. The highest surface roughness (Group B) was observed with 60-mesh particles, 0.4 MPa pressure, a distance of 100 mm, and a duration of 15 seconds. Conclusion Within the range of parameter levels examined in this study, surface roughness decreased with increasing particles size and blasting time, while it increased with higher pressure and longer blasting distance.
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    Effect of platelet-rich fibrin on bone regeneration
    Huang Lirong, Feng Zeru, Wu Hongkun, Mo Anchun
    Chinese Journal of Oral Implantology    2025, 30 (2): 118-126.   DOI: 10.12337/zgkqzzxzz.2025.04.005
    Abstract251)      PDF (1410KB)(409)       Save
    Platelet-rich fibrin (PRF), a second-generation autologous platelet concentrate, has been widely used in oral implantology and maxillofacial surgery due to its excellent biocompatibility and bone regeneration capacity. PRF facilitates osteoblast activation, angiogenesis, and bone remodeling by sustained release of growth factors through its three-dimensional fibrin network. It has shown significant potential in sinus floor elevation, bone augmentation, extraction site preservation, and immediate implant placement, improving implant stability and survival rates. Additionally, PRF has shown efficacy in the treatment of medication-related osteonecrosis of the jaw (MRONJ) by reducing infection, alleviating inflammation, and promoting tissue healing. However, PRF's clinical outcomes are influenced by individual physiological differences, preparation methods, and degradation rates. PRF's long-term osteogenic effects, especially in severe bone defects, remain inconsistent. Optimizing centrifugation parameters, blood collection tube materials, and fiber structure, as well as combining PRF with bone grafts, antimicrobial drugs, and biomimetic scaffolds, can enhance its performance. Additionally, PRF combined with nanomaterials and hydrogel scaffolds shows potential advantages in angiogenesis and tissue regeneration, though long-term follow-up data remain limited. In conclusion, PRF holds significant promise in bone regeneration. However, further studies are required to establish standardized preparation protocols and multidisciplinary strategies to improve its clinical stability and efficacy.
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    Research progress on the bone window in lateral window technique for sinus floor elevation
    Zhang Heng, Zhou Yiqun
    Chinese Journal of Oral Implantology    2025, 30 (2): 187-192.   DOI: 10.12337/zgkqzzxzz.2025.04.014
    Abstract248)      PDF (1276KB)(262)       Save
    The lateral window technique for sinus floor elevation is a key approach to address insufficient alveolar bone height in posterior maxillary implant surgery, and research in this area has been continuously advancing. With ongoing improvements in bone window design and the application of digital technology, significant progress has been made in reducing intraoperative complications, minimizing postoperative trauma, enhancing osteogenesis, and increasing implant survival rates. This review summarizes the design aspects of the bone window, including its shape, size, and position, as well as the application of digital technology in the lateral window technique for sinus floor elevation, aiming to provide a reference for bone window selection in this surgical procedure.
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    Comparison of the effectiveness of different abutments combined with all-ceramic crowns for the restoration of anterior tooth loss in patients
    Zhao Weiju, Yao Shubin, Wang Yating
    Chinese Journal of Oral Implantology    2025, 30 (1): 68-73.   DOI: 10.12337/zgkqzzxzz.2025.02.012
    Abstract245)      PDF (1466KB)(275)       Save
    Objective To compare and analyze the effectiveness of individualized all-ceramic abutments versus individualized pure titanium abutments in combination with all-ceramic crowns for the restoration of anterior tooth loss. Methods Clinical data from 76 patients (85 missing tooth sites) with anterior tooth loss, treated at Jinshui Huici Hospital from October 2022 to August 2023, were retrospectively collected for a case-control study. Patients were divided into two groups based on the treatment method: the pure titanium group (38 patients, 41 missing tooth sites), which received individualized pure titanium abutments combined with all-ceramic crowns, and the all-ceramic group (38 cases, 44 missing tooth sites),which received individualized all-ceramic abutments combined with all-ceramic crowns. The health status of the dental implants, including the peri-implant soft tissue index and plaque index (PLI), was evaluated at different time points (1 month, 3 months, and 6 months after treatment). Additionally, quality of life was assessed before and 6 months after treatment using the oral health impact profile-14 (OHIP-14), and the satisfaction with the prosthetic restoration was measured using the red aesthetic score (PES) and white aesthetic score (WES). The incidence of complications was also compared between the groups. Results Repeated measures analysis of variance showed a significant difference in the interaction effects of peri-implant soft tissue index and PLI between the two groups at different time points ( P<0.05). Analysis of the time effect indicated that both groups showed an increasing trend in the soft tissue index and PLI at 3 and 6 months after treatment ( P<0.05). Group effect analysis showed that the soft tissue index and PLI were lower in the all-ceramic group than in the pure titanium group at 3 and 6 months after treatment ( P<0.05). At six months after treatment, the quality of life in both groups improved, and the OHIP-14 score in the all-ceramic group was lower than in the pure titanium group ( P<0.05). Satisfaction with the prosthetic restoration, as measured by PES and WES, was also significantly higher in the all-ceramic group than in the pure titanium group ( P<0.05). There was no significant difference in the incidence of complications between the two groups ( P>0.05). Conclusion Compared with individualized pure titanium abutments, the use of individualized all-ceramic abutments combined with all-ceramic crowns in patients with anterior tooth loss results in better soft tissue health around the implant, improved quality of life, and higher patient satisfaction with the restoration.
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    The commemoration ceremony for the 10 th anniversary of the death of Professor Brånemark, the father of modern dental implantology
    Hospital of Stomatology, Air Force Military Medical University
    Chinese Journal of Oral Implantology    2024, 29 (6): 502-503.   DOI: 10.12337/zgkqzzxzz.2024.12.001
    Abstract239)      PDF (1625KB)(538)       Save
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    Application of stereophotogrammetry in complete-arch implant impression making: a literature review
    Lei Yanxi, Yuan Quan, Lyu Mingyue
    Chinese Journal of Oral Implantology    2024, 29 (6): 590-595.   DOI: 10.12337/zgkqzzxzz.2024.12.023
    Abstract238)      PDF (1578KB)(390)       Save
    The accuracy of impressions is closely related to the passive fit of complete-arch implant-supported prostheses, which significantly affects their long-term outcomes. Conventional open-tray impression techniques have been recognized for their high accuracy in full-arch implant restorations and are still regarded as the gold standard. However, with the ongoing advancements in digital technology, stereophotogrammetry (SPG) has been introduced for digital impression-making in complete-arch implant cases. Compared to the traditional open-tray technique, SPG offers advantages such as reduced chair time, increased patient comfort, and a simplified workflow. Despite these benefits, the accuracy of SPG remains a topic of debate. This article reviews the principles and methods of SPG, its in vivo and in vitro applications, and factors influencing impression accuracy, to provide a reference for further development of SPG in implant dentistry.
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    Research on the utilization of sticky bone in bone regeneration
    Liang Yixin, Qu Zhe
    Chinese Journal of Oral Implantology    2025, 30 (2): 111-117.   DOI: 10.12337/zgkqzzxzz.2025.04.004
    Abstract237)      PDF (1622KB)(569)       Save
    The high concentrations of growth factors within platelets have been proven to promote cell migration, proliferation, and angiogenesis during the regeneration process. Multiple efforts have been exerted to blend them with bone substitute materials, to fabricate "sticky bone" for easier manipulation by surgeons. While autologous and allogeneic bone grafts are limited by donor site availability and biocompatibility issues, synthetic bone grafts exhibit significant advantages in terms of biocompatibility. The integration of growth factors into these porous synthetic grafts can effectively stimulate cell growth and differentiation, thereby enhancing osteogenic potential. This paper reviews the research and advancements in sticky bone for bone regeneration, elaborating on the fabrication and characterization of sticky bone materials. Moreover, it also highlights the promising outcomes and benefits of sticky bone in bone defect regeneration, substantiated by clinical data from both domestic and international studies.
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    Oral implantology and medication-related osteonecrosis of the jaw (MRONJ)
    Su Yucheng
    Chinese Journal of Oral Implantology    2025, 30 (4): 317-330.   DOI: 10.12337/zgkqzzxzz.2025.08.001
    Abstract236)      PDF (2181KB)(259)       Save
    Medication-related osteonecrosis of the jaw (MRONJ) has emerged as a serious complication associated with antiresorptive therapy and anti-angiogenic therapy, and has received increasing attention in recent years.In implant patients, severe MRONJ can lead to devastating consequences for the jawbone, with few effective preventive strategies currently available.Although a substantial body of literature on MRONJ exists, it often lacks systematic organization.Therefore, this review discusses the definition, incidence, etiology and pathogenesis, staging, diagnostic criteria, histopathological manifestations, risk factors, prevention, and treatment strategies for MRONJ. Special emphasis is placed on the risks and management of peri-implant MRONJ (PI-MRONJ). Despite the lack of consensus on many aspects of MRONJ, the objective discussion in this article presents current research progress to clinicians and provide references for the prevention and treatment of MRONJ and PI-MRONJ.
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    Finite element analysis of a novel 3D-printed temporary fixed prosthesis for edentulous jaws under multidirectional loading
    Zhang Chuankai, Zhang Jiayuan, Pan Yulei, Chen Qingsheng, Lin Haiyan
    Chinese Journal of Oral Implantology    2025, 30 (2): 135-143.   DOI: 10.12337/zgkqzzxzz.2025.04.007
    Abstract234)      PDF (1550KB)(254)       Save
    Objective This study aimed to investigate the biomechanical properties of a novel 3D-printed temporary fixed denture for edentulous jaws using finite element analysis, and to compare its mechanical performance with that of conventional non-3D-printed polyetheretherketone (PEEK) and 3D-printed polylactic acid (PLA). Methods A three-dimensional finite element model of a mandible with complete edentulism was established based on a patient treated with an implant-supported temporary fixed prosthesis at Hangzhou Stomatological Hospital (Pinghai Campus) in May 2024. Three materials were analyzed: polyetheretherketone (PEEK, A1), polylactic acid (PLA, A2), and 3D-printed light-curing temporary crown and bridge resin for additive manufacturing (A3). A static load of 150 N was applied to anterior and posterior crowns and bridges in eight different directions: vertical load on posterior teeth (G1), right posterior buccal-to-lingual load (G2), right posterior lingual-to-buccal load (G3), left posterior buccal-to-lingual load (G4), left posterior lingual-to-buccal load (G5), vertical load on anterior teeth (G6), anterior labial-to-lingual load (G7), and anterior lingual-to-labial load( G8). Finite element analyses were performed using ANSYS 2021 R1 to evaluate the maximum Von Mises stress (MPa), maximum total deformation (mm), maximum Von Mises strain (mm), and stress distribution maps for each material. Results ①The maximum Von Mises stress of A1 (PEEK) was lower than A2 (PLA) in all directions, and A3 exhibited lower Von Mises stress than A2 in five directions.② A3 demonstrated lower maximum total deformation and Von Mises strain than A1 and A2 in seven directions; however, in direction G6 (vertical load on anterior teeth), A3 exhibited the largest total deformation and Von Mises strain. ③For anterior loading, the greatest deformation was concentrated at the incisal edge, with Von Mises strain evenly distributed across the anterior teeth and stress concentrated around the connector of the prosthesis.④For posterior loading, the greatest deformation was located at the distal margin of the mandibular second molar, with relatively uniform strain distribution in posterior regions, and peak stress located at the implant-abutment connection. Conclusion The novel 3D-printed temporary fixed denture for edentulous jaws demonstrated partially superior mechanical properties compared to both PEEK and PLA materials under simulated functional loading.
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    Careful planning and prudent selection in implant therapy for patients with periodontitis
    Hu Wenjie
    Chinese Journal of Oral Implantology    2024, 29 (6): 583-584.   DOI: 10.12337/zgkqzzxzz.2024.12.021
    Abstract230)      PDF (1481KB)(200)       Save
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    Advances in basic and clinical research on the socket-shield technique
    Feng Shenghui, Pan Xiaobo, Tang Zengbin, Long Xiaojie, Yang Yujie
    Chinese Journal of Oral Implantology    2025, 30 (2): 169-175.   DOI: 10.12337/zgkqzzxzz.2025.04.011
    Abstract228)      PDF (1636KB)(341)       Save
    Achieving predictable aesthetic outcomes in implant restoration of the anterior zone remains a major challenge, particularly in preserving and reconstructing the peri-implant soft and hard tissues to ensure harmony with adjacent teeth. The socket-shield technique (SST) effectively maintains the alveolar ridge contour and reduces soft tissue collapse by preserving the biological integrity of the bundled bone-periodontal ligament complex. This technique enhances the aesthetic outcomes of implant therapy. This article summarizes and discusses the background, evidence-based support, clinical applications, and prognosis of SST, aiming to provide a reference for clinical dentists performing anterior implant restoration.
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    The application of platelet-rich fibrin in peri-implant soft tissue augmentation
    Fu Li, Zhou Yanmin
    Chinese Journal of Oral Implantology    2025, 30 (2): 98-105.   DOI: 10.12337/zgkqzzxzz.2025.04.002
    Abstract225)      PDF (1651KB)(369)       Save
    Soft tissue augmentation is an effective technique for improving both the quality and contour of peri-implant soft tissues. The selection of surgical procedures and materials has been a major focus of ongoing research. In recent years, the application of platelet-rich fibrin (PRF) in soft tissue augmentation procedures has garnered significant attention. However, there remains a lack of systematic discussion regarding its indications, application methods, and clinical outcomes. This article reviews the clinical strategies for soft tissue augmentation, and explores the mechanisms, research progress, and clinical effects related to PRF in peri-implant tissue augmentation, aiming to provide valuable insights for clinical application.
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    Analysis of implant survival rates at different subantral residual bone heights in simultaneous implant placement with lateral window technique for sinus floor elevation
    Chen Gang
    Chinese Journal of Oral Implantology    2024, 29 (6): 531-536.   DOI: 10.12337/zgkqzzxzz.2024.12.011
    Abstract222)      PDF (2061KB)(291)       Save
    Objective To evaluate the impact of subantral residual bone height (SRBH) on implant survival rates during simultaneous implant placement with the lateral window technique for sinus floor elevation. Methods A retrospective cohort study was conducted on patients treated at Shenzhen U-Dental Clinic between April 2012 and April 2022. These patients, with insufficient bone volume in the maxillary posterior region, underwent the lateral window technique for sinus floor elevation with simultaneous implant placement using bovine-derived inorganic bone graft material. Secondary prosthetic restoration was performed 6 months postoperatively. Patients were divided into two groups based on SRBH: Group 1 (<3 mm) and Group 2 (≥3 mm). Postoperative complications, implant survival rates, and marginal bone loss were evaluated. Results A total of 124 patients underwent 136 maxillary sinus surgeries with 252 implants placed. The mean follow-up period was 58.1±15.8 months. Implant survival rates were 91.59% in Group 1 and 93.10% in Group 2, with no statistically significant difference between the groups. Sinus membrane perforation occurred in 27 cases (19.85%), but it was not significantly associated with implant failure. Conclusion Simultaneous implant placement with the lateral window technique for sinus floor elevation is an effective treatment for insufficient bone height in the maxillary posterior region. There is no significant correlation between SRBH and implant survival rates.
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    Exploration of the clinic application of dental post-processing module of cone beam CT images within the picture archiving and communication system (PACS)
    Zheng Hao, Pan Xiao, Lin Zitong
    Chinese Journal of Oral Implantology    2025, 30 (1): 40-46.   DOI: 10.12337/zgkqzzxzz.2025.02.008
    Abstract220)      PDF (1523KB)(398)       Save
    Objective To explore the clinical application of a dental post-processing module for cone beam CT (CBCT) images embedded within the picture archiving and communication system (PACS) for preoperative implant evaluation. Methods A PACS-embedded dental post-processing module, including curved planar reformation (CPR) and continuous multi-axis dental reconstruction, was developed. A total of 270 CBCT images from implant patients in our hospital (scanned using three different CBCT systems, 90 cases per system) were analyzed by a radiologist for bone volume assessment. Method1 used CBCT digital imaging and communication in medicine (DICOM) data uploaded to PACS, applying the embedded dental post-processing module for reconstruction and measurement. Method2 utilized CD-ROM data exported from each CBCT device along with the corresponding built-in image processing software. The durations of image upload, opening, post-processing, and total time for both methods were recorded and statistically analyzed. Consistency in bone volume measurements was assessed, and a questionnaire on user satisfaction was completed by 10 radiologists and implantologists. Results Significant differences in image processing times were observed between the two methods for all three CBCT systems. Method1 significantly reduced total processing time compared to Method2 ( P<0.001), with consistent bone volume measurement results between the two methods. User satisfaction surveys indicated that Method1 was superior to Method2 ( P<0.001). Conclusion The PACS-embedded post-processing module is suitable for CBCT image analysis and measurement in implant patients, significantly enhancing clinical efficiency.
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    Comparison of trapezoidal full-thickness flap and combination flap in guided bone regeneration in the posterior mandible
    Hu Xiucheng, Sun Shichen, Wu Binbin, Wu Dan, Sun Haipeng
    Chinese Journal of Oral Implantology    2025, 30 (2): 144-150.   DOI: 10.12337/zgkqzzxzz.2025.04.008
    Abstract219)      PDF (1397KB)(413)       Save
    Objective This study aimed to investigate the clinical advantages and disadvantages of two flap advancement techniques, trapezoidal full-thickness flap (TFF) and combination flap (CF), in guided bone regeneration (GBR) in the posterior mandible, and to compare the differences in postoperative pain and swelling levels between the two techniques. Methods A retrospective analysis was conducted on 89 patients who underwent single posterior mandibular implant placement with simultaneously guided bone regeneration in our hospital from September 2023 to May 2024. The patients were divided into two groups according to the flap advancement technique: the TFF group (47 patients) and the CF group (42 patients). The two groups were compared in terms of the need for additional vertical incisions, the use of additional fixation devices such as membrane fixation screws, and the incidence of accidental flap perforation. Postoperative pain and swelling were recorded for one week following surgery in both groups. Results During surgery, all cases in the TFF group required vertical incisions extending beyond the mucogingival junction. In the CF group, 13 cases (31.0%) did not require additional vertical incisions, and 29 cases(69.0%)required small vertical incisions terminating at the mucogingival junction. No flap perforations occurred in the TFF group, while in the CF group, there were 2 cases (4.8%) of accidental flap perforation during periosteal incision and flap release. For collagen membrane fixation, in the TFF group, 22 cases (46.8%) used membrane fixation screws at the crest, and 25 cases (53.2%) used screws at the apex; in the CF group, 18 cases (42.9%) used membrane fixation screws at the crest, but no screws were needed at the apex. No postoperative infections or bone graft material exposure were observed in either group. Although pain levels were lower in the TFF group compared to those in the CF group on postoperative days 1, 3, 5, and 7, no statistically significant difference was observed between the two groups ( P>0.05). Similarly, while swelling levels were lower in the TFF group than in the CF group on postoperative days 1, 3, and 5, no statistically significant difference was found between the two groups ( P>0.05). However, on postoperative day 7, swelling was significantly lower in the TFF group than in the CF group ( P<0.05). Conclusion Both techniques could achieve effective flap advancement and primary wound closure following GBR procedures. There was no significant difference in postoperative pain between the two groups during the entire observation period, and no significant difference in swelling on postoperative days 1, 3, and 5, except that swelling in the CF group was slightly more severe than in the TFF group on postoperative day 7. As a modified flap advancement technique, CF is more technically sensitive than the classic TFF. However, when CF is applied in the posterior mandible, it can reduce the use of additional vertical incisions, which benefits blood supply and reduces surgical invasiveness. Additionally, it can retain the collagen membrane by using the apical periosteal "pocket", thus eliminating the use of membrane fixation screws at the apex of the surgical area and decreasing the risk of damaging adjacent anatomical structures. Therefore, the combination flap technique has good clinical applicability and potential for widespread adoption.
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    Research progress on the effects of osteoblast/osteoclast axis on bone metabolism in diabetes mellitus
    Wang Ziyang, Ma Xudong
    Chinese Journal of Oral Implantology    2025, 30 (2): 176-179.   DOI: 10.12337/zgkqzzxzz.2025.04.012
    Abstract214)      PDF (1256KB)(423)       Save
    The osteoblast/osteoclast axis is a key regulatory system in bone metabolism, in which osteoblasts and osteoclasts interact and regulate each other through multiple signaling pathways to maintain skeletal homeostasis. Diabetes mellitus is a metabolic disease characterized by absolute or relative insulin deficiency, leading to impaired osseointegration and reduced success rates of implant therapy. This paper reviews the biological role of the osteoblast/osteoclast axis and the impact of diabetes mellitus on its regulation. It also discusses potential strategies for modulating this axis to enhance osseointegration in diabetic patients and improve the clinical success of implant treatment.
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    Application of bone densification technique combined with plasma matrix in transalveolar technique for sinus floor elevation
    Wang Yulan, Zeng Hao, Xia Ting, Zhang Yufeng
    Chinese Journal of Oral Implantology    2025, 30 (2): 106-110.   DOI: 10.12337/zgkqzzxzz.2025.04.003
    Abstract211)      PDF (1496KB)(414)       Save
    The patient had been missing right maxillary posterior teeth for several months and requested implant restoration. CBCT examination revealed an alveolar bone height of less than 5 mm in the edentulous area, an inclined sinus floor morphology, and low bone density. A combination of bone densification technique and plasma matrix was used to perform transalveolar sinus floor elevation and implant placement simultaneously. No sinus membrane perforation occurred intraoperatively, and no postoperative infections or complications were observed. A six-month follow-up showed successful osseointegration, sufficient bone volume, and smooth completion of the second-stage surgery, impression-taking, and final prosthetic restoration. In this case, the bone densification technique enhanced bone density by compacting bone and elevating the sinus membrane. The plasma matrix, rich in growth factors, effectively protected the sinus membrane, reduced potential complications, and improved bone regeneration outcomes.
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    Effectiveness of concentrated growth factors in sinus floor elevation: a review
    Ou Yanjing, Chen Jiang
    Chinese Journal of Oral Implantology    2024, 29 (6): 596-601.   DOI: 10.12337/zgkqzzxzz.2024.12.024
    Abstract211)      PDF (1642KB)(371)       Save
    Maxillary sinus floor elevation has become a routine procedure for addressing insufficient bone volume in the atrophic posterior maxilla. Various bone grafting materials, including autologous bone, allografts, xenografts, and synthetic bone substitutes, have been used to achieve adequate bone augmentation for dental implant placement. Concentrated growth factor (CGF), a new generation of platelet concentrate, features a dense fibrin structure enriched with multiple growth factors that regulate cell adhesion, proliferation, differentiation, and angiogenesis. This review focuses on the effects of CGF on implant success rates, the quality of newly formed bone, and the incidence of postoperative complications in maxillary sinus floor elevation procedures.
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    Strive steadily and reach far, together we forge the future
    Su Yucheng
    Chinese Journal of Oral Implantology    2025, 30 (1): 1-2.   DOI: 10.12337/zgkqzzxzz.2025.02.001
    Abstract211)      PDF (1382KB)(307)       Save
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