Chinese Journal of Oral Implantology ›› 2024, Vol. 29 ›› Issue (4): 347-351.DOI: 10.12337/zgkqzzxzz.2024.08.009

• Key Column “Systemic Diseases and Dental Implant Treatment” • Previous Articles     Next Articles

The impact of diabetes on the soft tissue seal surrounding dental implants

Wang Qian1, Yuan Quan1,2   

  1. 1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital and School of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China;
    2Department of Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China
  • Received:2024-05-28 Online:2024-08-30 Published:2024-08-16
  • Contact: Yuan Quan, Email: yuanquan@scu.edu.cn, Tel: 0086-28-85503579
  • Supported by:
    National Natural Science Foundation of China (82125006)

Abstract: The soft tissue seal around the dental implants is recognized as a primary mucosal barrier against external stimuli and is critical for maintaining implant stability. Diabetes mellitus (DM) is a known risk factor for peri-implantitis. Persistent hyperglycemia can impair the barrier function of peri-implant soft tissues, leading to peri-implant diseases. Moreover, increased pathogenic bacterial infections, excessive inflammatory cytokine activity, and impaired wound healing in diabetic conditions may result in poor soft tissue sealing around implants. This review outlines the structure of peri-implant soft tissue sealing, explores the factors contributing to impaired soft tissue sealing in diabetes, and summarizes methods to improve the mucosal barrier in diabetic patients, providing guidance for implant treatment strategies in diabetic patients.

Key words: Mucosal barrier, Soft tissue seal, Diabetes mellitus, Dental implant, Peri-implant mucositis