糖尿病影响种植体周软组织封闭的研究进展

doi:10.12337/zgkqzzxzz.2024.08.009

摘要/Abstract

摘要： 种植体周软组织封闭被认为是抵御外界刺激的主要黏膜屏障,也是保持种植体稳定性的关键因素。糖尿病是种植体周炎的风险因素之一。持续的高血糖易造成种植体周软组织的屏障功能障碍,从而诱发种植体周疾病。同时,糖尿病状态下致病菌感染增加、致炎细胞因子过度活跃和伤口愈合受损等可能导致种植体周软组织封闭不良。本文综述了种植体周软组织封闭的结构、糖尿病削弱种植体周软组织封闭的可能因素,并总结了改善糖尿病患者种植体周黏膜屏障的方法,以指导糖尿病患者种植治疗策略的制定。

关键词: 黏膜屏障, 软组织封闭, 糖尿病, 种植体, 种植体周黏膜炎

Abstract: The soft tissue seal around the dental implants is recognized as a primary mucosal barrier against external stimuli and is critical for maintaining implant stability. Diabetes mellitus (DM) is a known risk factor for peri-implantitis. Persistent hyperglycemia can impair the barrier function of peri-implant soft tissues, leading to peri-implant diseases. Moreover, increased pathogenic bacterial infections, excessive inflammatory cytokine activity, and impaired wound healing in diabetic conditions may result in poor soft tissue sealing around implants. This review outlines the structure of peri-implant soft tissue sealing, explores the factors contributing to impaired soft tissue sealing in diabetes, and summarizes methods to improve the mucosal barrier in diabetic patients, providing guidance for implant treatment strategies in diabetic patients.

Key words: Mucosal barrier, Soft tissue seal, Diabetes mellitus, Dental implant, Peri-implant mucositis

王倩,等袁泉. 糖尿病影响种植体周软组织封闭的研究进展[J]. 中国口腔种植学杂志, 2024, 29(4): 347-351. DOI: 10.12337/zgkqzzxzz.2024.08.009

Wang Qian, Yuan Quan. The impact of diabetes on the soft tissue seal surrounding dental implants[J].Chinese Journal of Oral Implantology, 2024, 29(4): 347-351.DOI: 10.12337/zgkqzzxzz.2024.08.009.

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