中国口腔种植学杂志 ›› 2024, Vol. 29 ›› Issue (4): 342-346.DOI: 10.12337/zgkqzzxzz.2024.08.008

• “全身系统性疾病与牙种植”重点栏目 • 上一篇    下一篇

抑郁症对种植体周健康状态影响的研究进展

赵昕彤, 孟维艳   

  1. 吉林大学口腔医院口腔种植科,长春 130000
  • 收稿日期:2024-06-14 出版日期:2024-08-30 发布日期:2024-08-16
  • 通讯作者: 孟维艳,Email:mengwy@jlu.edu.cn,电话:0431-88796025
  • 作者简介:赵昕彤, 硕士研究生在读,研究方向:口腔种植相关临床研究; 孟维艳, 主任医师、教授、博士研究生导师,研究方向:美学区、数字化口腔种植相关临床研究及种植体表面改性、种植体周炎等相关基础研究
  • 基金资助:
    吉林省产业技术研究与开发项目(2023C041-3); 吉林省自然科学基金项目(YDZJ202201ZYTS244); 吉林省科技发展计划项目(20200404108YY)

Research progress on the influence of depression on peri-implant health

Zhao Xintong, Meng Weiyan   

  1. Department of Dental Implantology, Hospital of Stomatology, Jilin University, Changchun 130000, Jilin, China
  • Received:2024-06-14 Online:2024-08-30 Published:2024-08-16
  • Contact: Meng Weiyan, Email: mengwy@jlu.edu.cn, Tel: 0086-431-88796025
  • Supported by:
    Jilin Province Industrial Technology Research and Development Projec (2023C041-3); Jilin Province Natural Science Foundation Project (YDZJ202201ZYTS244); Jilin Province Science and Technology Development Plan Project (20200404108YY)

摘要: 近年来,口腔种植修复已经成为修复缺失牙的重要方式,种植体的长期留存率受全身及局部多种因素的影响。抑郁症是一种常见的心理疾病,患病率较高,患者在进行口腔种植修复治疗时,植入手术后软硬组织愈合过程常会受到影响。抑郁症常导致口腔菌群失调,易引发种植体周炎并加速其发展,影响种植远期疗效,抗抑郁药也会影响种植体周骨结合。本文就抑郁症对种植体植入后软硬组织愈合过程、骨代谢及口腔微生物组等的影响进行综述,以期为抑郁症患者口腔种植修复治疗风险评估及诊疗策略制定提供参考。

关键词: 抑郁症, 牙种植, 组织愈合, 微生物, 骨代谢

Abstract: In recent years, implant-supported prostheses have become an important method for repairing missing teeth. However, the long-term survival rate of implants is affected by various systemic and local factors. Depression is a common mental disease with a high prevalence rate, which affects the healing process of soft and hard tissues after implant surgery. Moreover, depression often leads to oral dysbiosis, which can easily promote the occurrence and development of peri-implantitis and affect the long-term efficacy of implants. Antidepressants, such as SSRIs, also affect osseointegration. This article aims to review the effects of depression on the healing process of soft and hard tissues, bone metabolism, and oral microbiome after implantation, hoping to provide a clinical basis for the risk assessment and treatment strategy of implant treatment for patients with depression.

Key words: Depression, Dental implant, Tissue healing, Microbiome, Bone metabolism