种植体周炎在鼠类实验模型构建的研究进展

doi:10.12337/zgkqzzxzz.2025.06.013

摘要/Abstract

摘要： 种植体周炎是口腔种植修复最棘手的并发症,也是直接导致种植体失败的主要原因。成功构建相关动物实验模型是研究种植体周炎发病机制的重要工具。本综述从实验动物的选择、建模方法、建模时间、建模结局指标评价及建模成功率等方面总结了近年来对种植体周炎鼠类实验模型构建的研究进展,旨在为种植体周炎的动物模型构建提供更好的参考和帮助。

关键词: 种植体周炎, 鼠类, 动物实验模型

Abstract: Peri-implantitis is one of the most intractable complications in dental implant treatment, which is also the key factor for implant failure. The construction of relevant animal experimental models that can accurately simulate the pathological features of peri-implantitis is crucial for in-depth exploration of its pathogenesis. This review systematically collates the research progress in recent years on the establishment of murine experimental models of peri-implantitis. The content encompasses the scientific selection of experimental animals, the application of innovative modeling methods, modeling time, the accurate evaluation of modeling outcome indicators, and an in-depth analysis of key factors such as success rate. The aim is to provide more comprehensive and accurate references for researchers in this field.

Key words: Peri-implantitis, Murine, Animal model

孙雨欣,施斌,吴涛. 种植体周炎在鼠类实验模型构建的研究进展[J]. 中国口腔种植学杂志, 2025, 30(3): 281-287. DOI: 10.12337/zgkqzzxzz.2025.06.013

Sun Yuxin, Shi Bin, Wu Tao. Research progress in the construction of murine experimental model of peri-implantitis[J].Chinese Journal of Oral Implantology, 2025, 30(3): 281-287.DOI: 10.12337/zgkqzzxzz.2025.06.013.

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