关键词: 牙种植体, 骨结合, 成骨细胞, 涂层材料

Abstract: Osseointegration of implants is defined as the direct structural and functional connection between a loaded implant and the surrounding ordered bone tissue. This process is complex, involving the interactions among multiple cell types. Osteoblasts adhere to, proliferate on, and differentiate at the implant surface, and through a sequence of biological processes, they facilitate the integration of the implant with the adjacent bone tissue—an event pivotal to osseointegration. Robust osseointegration enhances implant stability, reduces the risk of infection, and thereby increases the success rate of restoration and improving patients’ quality of life. However, studies indicate that diabetes can impede the osseointegration process and lower the implant success rate. To enhance osseointegration in diabetic patients, researchers have developed a variety of novel materials and techniques, including continuous antibacterial materials, biological factor sustained-release materials and surface modification techniques. Among these, implant surface treatment has attracted significant attention due to its ability to improve osseointegration performance while enhancing biocompatibility and antibacterial properties. This article reviews the principles and efficacy of various implant surface treatment methods, such as mechanical treatments, coating technologies, and biomaterial scaffolds.

Key words: Dental implants, Osseointegration, Osteoblast, Coated materials