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    Recent advances in the factors affecting the pathogenesis, diagnosis, and treatment of peri-implantitis
    Yan Fuhua, Song Shiyuan
    Chinese Journal of Oral Implantology    2023, 28 (6): 402-409.   DOI: 10.12337/zgkqzzxzz.2023.12.003
    Abstract1878)      PDF (1334KB)(4694)       Save
    Oral implant therapy is one of the most common methods for restoring defective and missing dentition. Peri-implantitis is a prevalent biological complication of implant therapy, characterized by inflammation of the peri-implant mucosa and subsequent progressive loss of supporting bone. The occurrence of peri-implantitis can impact the prognosis of implant restorations or even lead to implant failure, significantly affecting the patient's health and quality of life. Therefore, reducing the risk factors of peri-implantitis, timely diagnosis and effective treatments are of great importance to enhance the prognosis of implant therapy. This review describes the factors influencing the pathogenesis of peri-implantitis, the current diagnostic criteria, and therapeutic methods. Furthermore, it discusses emerging treatment modalities with potential clinical applications and reviews ongoing research progress.
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    Research advances in the production process of dental collagen membrane
    Shu Qianyi, Su Yucheng
    Chinese Journal of Oral Implantology    2022, 27 (6): 358-364.   DOI: 10.12337/zgkqzzxzz.2022.12.006
    Abstract762)      PDF (1076KB)(4127)       Save
    Guided bone regeneration (GBR) is an important technique in implant dentistry, in which oral collagen membranes play a key role. According to the production process, oral collagen membranes can be divided into acellular matrix membranes, purified collagen membranes and recombinant collagen membranes. At present, acellular membranes are main ones used clinically. Different types of collagen membranes have similarities and differences in production processes, and different production processes also have different effects on the properties of collagen membranes. This paper reviews the classification, production processes, comparison of different collagen membranes and the improvement of collagen membranes.
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    Treatment decision-making and prognosis assessment of peri-implantitis
    Xu Shulan, Zhu Yuanxi
    Chinese Journal of Oral Implantology    2023, 28 (6): 394-401.   DOI: 10.12337/zgkqzzxzz.2023.12.002
    Abstract791)      PDF (1706KB)(4040)       Save
    Peri-implantitis is a common biological complication of dental implant treatment, and it is one of the significant causes of implant failure as well. The treatment decision-making and prognosis assessment of peri-implantitis present two major problems for implantologists in clinical practice. Evidence-based treatment decision-making and accurate prognosis assessment could help doctors propose appropriate treatment approaches and guide patients to conduct oral self-care and systemic factors control according to their own conditions, aiming for more a streamlined treatment process and better clinical outcomes. This literature review provides a comprehensive overview of the treatment decision-making and prognosis assessment of peri-implantitis, discusses its research progress and clinical recommendations, and puts forth suggestions for further research.
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    Biological principle of emergence profile design of implant prosthesis
    Yang Yufei, Gu Xinhua
    Chinese Journal of Oral Implantology    2022, 27 (6): 352-357.   DOI: 10.12337/zgkqzzxzz.2022.12.005
    Abstract715)      PDF (1106KB)(3012)       Save
    The emergence profile design of the implant prosthesis will not only affect the aesthetic effect of the prosthesis, but also affect the health of the tissues around the implant. Good emergence profile design helps to form a perfect soft tissue barrier, prevent microbial invasion, protect surrounding soft and hard tissues, and avoid aesthetic and biological complications. On the basis of understanding the biological characteristics of the tissue around the implant and based on the patient's soft and hard tissue conditions, designing a reasonable implant placement position to protect the health of the tissue around the implant is crucial to the success of the implant and also a necessary factor for the design of the emergence profile.
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    Surface decontamination in peri-implantitis management
    Dong Xiaoxiao
    Chinese Journal of Oral Implantology    2023, 28 (6): 437-443.   DOI: 10.12337/zgkqzzxzz.2023.12.008
    Abstract316)      PDF (1359KB)(2606)       Save
    Surface decontamination of implants is much more difficult than that of natural teeth. Incomplete decontamination is the main reason causing peri-implantitis treatment failure. This article reviews the implant surface decontamination modalities: mechanical decontamination methods, chemical decontamination methods and physical methods. Mechanical decontamination methods are the treatment most well documented. It is the foundation for peri-implantitis treatment. Nowadays, there is no gold standard for management of peri-implantitis. A combination of different decontamination modalities is recommended.
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    Root cause analysis of 3 cases of adverse events involving swallowing and aspiration in dental implant procedures
    Jiao Mingxiu, Bao Xianjing, Chen Haixia
    Chinese Journal of Oral Implantology    2023, 28 (5): 347-350.   DOI: 10.12337/zgkqzzxzz.2023.10.009
    Abstract434)      PDF (1400KB)(2470)       Save
    Objective The retrospective analysis was conducted on three cases of adverse events involving swallowing and aspiration in our hospital by applying the root cause analysis method. Methods The root causes of the events were identified in terms of systematic processes by creating a cause-and-effect diagram. Results The root causes of these incidents were identified in the system process: the lack of standardized preventive measures, insufficient patient evaluation, inadequate preoperative precautionary measures, and treatment positions that could easily result in swallowing and aspiration. Conclusion To address these three root causes, specific improvement measures were implemented: conducting adequate preoperative patient evaluations, enhancing preoperative precautionary measures, adjusting patient treatment positions, strengthening preventive measures during procedures, and enhancing supervision of such incidents.
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    Implant failure caused by mandible fibro-osseous lesions: a case report and the literature review
    Zhao Man, Zheng Yaqi, Yan Zhengbin, Li Xiaomin, Yang Xiaoyu
    Chinese Journal of Oral Implantology    2022, 27 (6): 346-351.   DOI: 10.12337/zgkqzzxzz.2022.12.004
    Abstract459)      PDF (1462KB)(2365)       Save
    A case of implanting in the bilateral mandibular posterior area simultaneously with different prognosis was reported. Finally, the implant on the right side was loose and removed after six months, which was failed without osseointegration. Otherwise, a good osseointegration was formed on the left side, and the implant was loaded routinely. In the right mandibular posterior area, there were fibro-osseous lesions with unremarkable imaging findings, which were finally diagnosed by histopathology. Mandible fibro-osseous lesions mainly refer to a mixture of pathological changes of fibrosis and ossification in technology. The performance of such lesions is not obvious or present with similar symptoms and radiographic appearances, which lead to difficulties in diagnosis. In this article, the causes of failure in this case were analyzed. Furthermore, the features of ossifying fibroma and fibrous dysplasia in clinical manifestation, radiology, histopathology and so on were reviewed in this article, in order to provide a risk assessment and early warning of implants with fibro-osseous lesions for clinic.
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    Research progress of the socket shield technique
    Luo Zhen, Liu Hong, Wu Wangxi
    Chinese Journal of Oral Implantology    2023, 28 (2): 119-123.   DOI: 10.12337/zgkqzzxzz.2023.04.009
    Abstract1292)      PDF (1177KB)(2201)       Save
    The socket shield technique is a new technology emerging in oral implantology in the last decade or so. Its introduction is to fundamentally interrupt the process of physiologic resorption in the alveolar socket after the tooth extraction. But no consensus has been reached on the standard operation and long-term effect of this treatment. Meanwhile with the development of digital technology, how to accurately and efficiently apply the socket shield technique has gradually attracted attention. The clinical procedure, the complication, the evaluation index and the digital application of the socket shield technique will be reviewed in this paper, hoping to provide a theoretical basis for the promotion of this technique in oral implantology.
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    A case of teeth extraction and immediate implants with the application of ridge splitting technique in anterior mandibular alveolar ridge
    Shi Wen, Wang Miaozhen, Liu Feng
    Chinese Journal of Oral Implantology    2022, 27 (6): 340-345.   DOI: 10.12337/zgkqzzxzz.2022.12.003
    Abstract678)      PDF (1500KB)(2067)       Save
    In the anterior mandibular aesthetic area, there is usually sufficient bone in the vertical direction and insufficient bone in the buccolingual and horizontal direction. In this paper, we present a case of a patient with multiple mandibular incisors to be extracted due to chronic periodontitis, in which the ridge splitting was applied to the anterior mandibular alveolar ridge with teeth extraction and immediate implant placement simultaneously. Teeth extraction, ridge splitting and implant placement were performed at the same time, and the second surgery was performed 6 months after the operation, and temporary restoration and permanent restoration were completed by digital technology 7 and 8 months after the first surgery.Teeth extraction and immediate implant placement with ridge splitting procedure allows the clinician to effectively augment the horizontal bone, improve implant success rate, reduce the number of operations and avoid a second operative area. The simultaneous application of ridge splitting technique with tooth extraction and implant placement with proper indications and operation details may have certain advantages over other implant options.
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    Influence factors of achieving predictable maxillary sinus bone augmentation
    Zhao Yang
    Chinese Journal of Oral Implantology    2024, 29 (3): 289-294.   DOI: 10.12337/zgkqzzxzz.2024.06.016
    Abstract2521)      PDF (1348KB)(2040)       Save
    Maxillary sinus floor elevation is a common surgical method to solve the problem of insufficient bone mass in the posterior maxillary region. Based on the special background of maxillary sinus bone augmentation, we explore the principles of achieving predictable maxillary sinus bone augmentation results from the mechanism of osteogenesis, which can be considered from four aspects: bone contact area, angiogenesis, stability of space, and safe healing.
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    The decision-making principles of sinus floor elevation (part 3)
    Pi Xuemin, Liu Qian, Chen Deping, Ren Bin, Pan Hong, Su Yucheng
    Chinese Journal of Oral Implantology    2023, 28 (1): 58-66.   DOI: 10.12337/zgkqzzxzz.2023.02.011
    Abstract475)      PDF (1350KB)(2034)       Save
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    Research progress of 3D printing individualized titanium mesh for complex bone augmentation
    Ji Ping
    Chinese Journal of Oral Implantology    2022, 27 (6): 334-339.   DOI: 10.12337/zgkqzzxzz.2022.12.002
    Abstract956)      PDF (1160KB)(1982)       Save
    Complex and severe alveolar bone defect is an important factor affecting the esthetic and long-term stability of dental implants. Compared to conventional bone augmentation, digital and custom bone augmentation could reduce operation time and improve the accuracy of bone augmentation. Three-D printing individualized titanium mesh (3D-PITM) shows good biocompatibility and space-making capacity, which could accurately reconstruct the alveolar bone contour. Thus, 3D-PITM has been gradually applied in the bone augmentation surgery. This paper introduces the application and research progress of 3D-PITM used for complex bone augmentation.
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    Characterization of peri-implant microbes and their changes under diseased conditions
    Liu Yue, Zhao Yajun, Liu Jin, Du Mi, Lan Jing
    Chinese Journal of Oral Implantology    2023, 28 (1): 35-39.   DOI: 10.12337/zgkqzzxzz.2023.02.007
    Abstract476)      PDF (1514KB)(1946)       Save
    Peri-implant disease is a biological complication that occurs in the peri-implant tissue with plaque biofilm as the initiating factor. The initial colonization, homeostasis, and dysbiosis of peri-implant submucosal microbes are closely related to the healthy and diseased states of the peri-implant. This article reviews the research on the characterization of peri-implant microbes and their changes in the diseased states. The results showed that there are significant differences in the structure of submucosal microbes between states of healthy peri-implant, peri-implant mucositis and peri-implantitis. The count of submucosal periodontal pathogens and the complexity of microbes increased when peri-implant disease occurred. The clinical manifestations of peri-implant disease were correlated with the variety in the type and quantity of microbes.
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    Expert consensus on titanium mesh supported guided bone regeneration
    Editorial Board of Chinese Journal of Oral Implantology
    Chinese Journal of Oral Implantology    2024, 29 (2): 95-100.   DOI: 10.12337/zgkqzzxzz.2024.04.001
    Abstract1025)      PDF (1401KB)(1799)       Save
    Nowadays, the clinical application of titanium mesh supported guided bone regeneration (TMs-GBR), especially using 3D printing individualized titanium mesh (3D-PITM), is increasing, serving as a reliable solution for bone augmentation in various cases of bone defects, particularly complex ones encountered during implant surgery. Given the technical sensitivity of TMs-GBR and the higher risk of complications such as titanium mesh exposure, as well as the current lack of relevant guidelines or international consensus, the editorial board of the Chinese Journal of Oral Implantology organized discussions among relevant experts and drafted this consensus, aiming to provide clinical reference for practitioners.
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    Application of socket-shield technique for immediate implant placement in aesthetic area
    Zhao Yaoyu, Yan Qi, Shi Bin
    Chinese Journal of Oral Implantology    2022, 27 (6): 376-380.   DOI: 10.12337/zgkqzzxzz.2022.12.009
    Abstract903)      PDF (1067KB)(1694)       Save
    Socket-shield technique has the advantages of maintaining alveolar bone dimension, reducing labial soft tissue recession and improving the aesthetic effect of restoration. An increasing number of oral implantology clinicians have become familiar with this technique in recent years. Through a literature review, this paper summarized and discussed the proposal and development of this technique, clinical operation process and medical evidence, so as to provide a reference for clinicians.
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    Reflections on the sole application of xenograft of low substitution rate for maxillary sinus floor elevation
    Wu Shiyu, Chen Zhuofan, Huang Baoxin, Chen Zetao, Liu Yuanxiang
    Chinese Journal of Oral Implantology    2023, 28 (5): 327-331.   DOI: 10.12337/zgkqzzxzz.2023.10.006
    Abstract342)      PDF (1455KB)(1666)       Save
    The maxillary sinus floor elevation is a key technique for restoring the vertical bone volume in the patient’s posterior region. However, the maxillary sinus floor elevation still has limitations such as significant trauma, sometimes requiring a second surgical area, and a long treatment cycle. These limitations are closely related to its osteogenic mechanism and the bone augmentation protocol. The article summarizes the evolution of the “gold standard” of bone augmentation materials for maxillary sinus floor elevation from the perspectives of spatial maintenance ability and new bone formation quality based on the mechanism of sinus cavity osteogenesis, then focuses on the current clinical application status of simply using deproteinized bovine bone matrix, in order to provide ideas for standardized clinical treatment and conversion research.
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    Decision tree for the selection of immediate restoration options after full-arch implant placement
    Peng Lingyan, Wang Yong, Su Yucheng
    Chinese Journal of Oral Implantology    2022, 27 (6): 381-386.   DOI: 10.12337/zgkqzzxzz.2022.12.010
    Abstract699)      PDF (1568KB)(1665)       Save
    Today, immediate fixed restoration after full-arch implant placement is being used by more and more clinicians and patients. New technologies, devices and software continue to emerge, and there is some confusion in clinical application. To standardize the application of this protocol and provide patients with a variety of options, according to the article “Immediate temporary restoration options after full-arch implant placement” published in June 2022 in this journal, the author team further establishes this decision tree to solve such clinical cases, with the aim of providing implant prosthetic dentists with advices and references of diagnosis and treatment, which dentists can adopt with a comprehensive decision-making based on clinical situation, dentist's experience, available equipment and software.
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    Application of platform technology in the treatment of peri-implantitis combined with implant infraposition in the aesthetic zone: a case report and literature review
    Lin Zhihui, Wang Xi, Man Yi
    Chinese Journal of Oral Implantology    2023, 28 (6): 424-429.   DOI: 10.12337/zgkqzzxzz.2023.12.006
    Abstract343)      PDF (1718KB)(1584)       Save
    In the process of long-term functional use of implant-supported dentures, the occurrence of peri-implant biological complications is often difficult to avoid due to various factors such as the patient's overall health condition, surgical procedures, implant restorations, and prosthetic techniques. Additionally, during the long-term clinical follow-up of patients with aesthetic zone implant restorations, it is often observed that the incisal edge of implant restoration is positioned lower towards the root compared to the contralateral natural tooth, indicating implant infraposition. This article reports a case of aesthetic zone implant peri-implantitis combined with implant infraposition treated using platform techniques. In this case, non-surgical treatment was used to control inflammation in the surgical area before the surgery, and connective tissue platform techniques were employed during the surgery to increase soft tissue volume around the implant. Temporary restoration was performed after 3 months postoperatively, followed by the final restoration after 6 months. Short-term treatment results showed that for cases of aesthetic zone implant peri-implantitis combined with implant infraposition, the use of connective tissue platform techniques can effectively achieve soft tissue reconstruction in the surgical area and reduce aesthetic risks.
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    Expert consensus on the clinical application of dental implant robots (first edition)
    Chen Jiang, Su Yucheng, Shen Guofang, Zhou Yanmin, Man Yi, Wu Yiqun, Yang Guoli, Zhang Yufeng, Tang Chunbo, Liu Qian, Fu Gang, Du Liangzhi, Liu Feng, Gao Yongbo, Yang Xingmei, Chen Deping, Chen Zhuofan, Xu Shulan, Wang Liping, Zhang Sihui
    Chinese Journal of Oral Implantology    2023, 28 (3): 134-139.   DOI: 10.12337/zgkqzzxzz.2023.06.002
    Abstract1171)      PDF (1438KB)(1572)       Save
    Dental implant robot is a new clinical technology in the field of dental implantology in recent years. In view of its high accuracy and stability, it has been applied in many professional fields of stomatology, such as dental implant, oral and maxillofacial surgery, etc. On the basis of clinical application and document retrieval, this consensus discusses the definition of related terms, clinical application requirements, operation specifications and risk prevention of dental implant robots, putting forward consensus views based on the clinical operation experience of some domestic experts.
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    Research advances in treatment of tooth agenesis
    Geng Chenxin, Liu Yang, Han Dong
    Chinese Journal of Oral Implantology    2024, 29 (3): 224-230.   DOI: 10.12337/zgkqzzxzz.2024.06.006
    Abstract496)      PDF (1368KB)(1527)       Save
    Tooth agenesis is the most common dental developmental anomaly in humans, which can cause significant chewing, pronunciation, aesthetic and craniofacial development problems. Due to the unique characteristics of tooth agenesis, its treatment is very time-consuming and costly, imposing huge economic burdens and mental stress on patients. The treatments include a sequential therapeutic strategy with a multidisciplinary team of pediatric dentistry, prosthodontics, oral and maxillofacial surgery, orthodontics, oral implantology, and other backgrounds, as well as emerging methods such as targeted molecular therapy and tissue engineering. This review provides an update on the knowledge on the characteristics of tooth agenesis, traditional treatments, and the rising fields of molecular therapy and tissue engineering. We also discuss the treatment effects of each method, aiming to provide a reference for the treatment of tooth agenesis.
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    The autologous platelet concentrates for maxillary sinus floor elevation: a meta-analysis of randomized controlled trials
    Zhao Ruimin, Gong Jiaming, Li Jianxue, Su Linhan
    Chinese Journal of Oral Implantology    2023, 28 (4): 270-278.   DOI: 10.12337/zgkqzzxzz.2023.08.011
    Abstract330)      PDF (1859KB)(1508)       Save
    Objective To systematically evaluate efficacy in the application of autologous platelet concentrates (APC) for maxillary sinus floor elevation (MSFE). Methods The databases of PubMed, Embase, Web of Science, Cochrane Library, CNKI, and Wanfang from 1 January 2000 to 30 September 2022, were electronically searched to identify randomized controlled trials (RCTs) involving MSFE employing APC. The Cochrane Tool was employed to assess the risk of bias. Data were analyzed via RevMan 5.4 software. Results In total 16 RCTs were included. Meta-analyses showed that at 6 months after MSFE, APC presented significant advantages in the proportion of new bone formation, grafted materials absorption, vertical bone augmentation, and bone density except for the proportion of connective tissue, bone-to-bone graft contact rate, vertical bone resorption, and implant stability quotient; At 12 months after MFSE, employing APC mixed grafted materials resulted in a significantly better vertical sinus-bone height than employing bone grafted materials alone, but the latter presented a more stable vertical sinus-bone height. Conclusion Limited evidence implied that during a medium-short follow-up period, employing APC mixed bone grafted materials achieves better performance than sole bone grafted materials in terms of the proportion of new bone formation, sinus-bone height, bone density, and materials degradation, thus, no positive efficacy on the proportion of connective tissue, bone-to-bone graft contact rate and the stability of vertical sinus-bone resorption and implant. Further evidence from RCTs with higher homogeneity and longer follow-up period is needed to evaluate its superiority in MSFE.
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    Selection of animal models simulating the human jawbone for in vivo experiments on oral implants
    Wang Qi, Teng Weiwei, Su Tianyue, Shu Qianyi, Li Cuiying, Wang Xinyu, Zhou Libo
    Chinese Journal of Oral Implantology    2023, 28 (4): 285-289.   DOI: 10.12337/zgkqzzxzz.2023.08.013
    Abstract423)      PDF (1258KB)(1463)       Save
    With the improvement of our national living standard and the popularization of dental implant technology, dental implants have become the first choice for the restoration of partially or completely edentulous jaws. To improve the surgical skill level of clinicians and develop excellent implants are important measures to improve the success rate of implant restorations, and neither physician training nor new implant development can be accomplished without preclinical experiments on animal models. Therefore, this paper reviews the animals and animal models suitable for dental implant surgery. The results of literature analysis show that there are a variety of animals that can be used to simulate the human jawbone for implant surgery or for testing the new implants developed. Pigs are the closest animal model to the human jawbone in terms of feeding habits, ethical considerations, physical size, temperament, structural characteristics, tissue composition, and bone remodeling of the jawbone tissue. However, due to the different experimental purposes, different animal models can be selected to carry out experiments. Additionally, an array of animal models can be concurrently employed to meet diverse research needs and achieve clinical treatment objectives.
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    Clinical procedure of transalveolar technique for sinus floor elevation
    Chen Deping, Liu Qian, Pi Xuemin, Pan Hong, Ren Bin, Su Yucheng
    Chinese Journal of Oral Implantology    2023, 28 (2): 128-132.   DOI: 10.12337/zgkqzzxzz.2023.04.011
    Abstract578)      PDF (1348KB)(1458)       Save
    The transalveolar technique for sinus floor elevation is a common surgical approach when there is insufficient vertical bone height in the maxillary posterior region for implant treatment. This article describes the evolution of this technique and the technical points of the clinical approach. It is very difficult to assess the intactness of the maxillary sinus mucoperiosteum in transalveolar technique when simultaneous bone augmentation is required. The use of electronic endoscope is a very helpful method to better confirm the preparation depth of the implant site and the status of the maxillary sinus mucoperiosteum, thus effectively avoiding complications of bone augmentation due to the maxillary sinus mucoperiosteum perforation. This article focuses on the clinical procedures and considerations in the use of transalveolar technique for sinus floor elevation to provide a reference for clinicians to improve the predictability of this technique.
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    Research progress on metal-organic frameworks in dental medicine
    Li Jian, Liang Ye, Zhao Baodong
    Chinese Journal of Oral Implantology    2024, 29 (6): 602-609.   DOI: 10.12337/zgkqzzxzz.2024.12.025
    Abstract652)      PDF (1601KB)(1385)       Save
    Metal-organic frameworks (MOFs) are nanoporous materials synthesized through the self-assembly of metal nodes and organic ligands. They are characterized by their highly ordered porosity, tunable pore size, large specific surface area, and diverse structures. With the advancements and applications of MOFs in the biomedical field, an increasing number of researchers have introduced MOFs into dental medicine for research. New MOFs have been tailored or developed based on the characteristics of the oral environment and diseases for use in oral disease treatment. The most commonly used MOFs in dentistry primarily include zeolitic imidazolate framework-8 (ZIF-8) and zeolitic imidazolate framework-67 (ZIF-67). The structure and function of MOFs are suitable for treating oral diseases, and they have shown promising results in researches related to periodontal disease, oral and maxillofacial tumors, dental pulp disease, and dental implants. However, their effectiveness still requires further validation through clinical trials.
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    Research progress on nano-silver antibacterial materials in the application in oral implantology
    Cheng Wen, Ma Xiaoting, Shen Yajie, Lv Shouyin, Shao Bo
    Chinese Journal of Oral Implantology    2023, 28 (1): 40-46.   DOI: 10.12337/zgkqzzxzz.2023.02.008
    Abstract680)      PDF (1498KB)(1328)       Save
    As a new type of highly effective nanometer antibacterial material, nano-silver has a broad-spectrum antibacterial ability, high antibacterial efficiency, and good anti-inflammatory properties. At present, it is widely used in various fields of stomatology. The antibacterial mechanism and application of nano-silver was reviewed for the field of oral implantology, and the antibacterial research prospect of nano-silver were forecasted.
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    Research progress on trace elements modification of PEEK implant
    Luo Guisheng, Liu Yumeng, Wang Penglai, Yuan Changyong
    Chinese Journal of Oral Implantology    2023, 28 (2): 109-113.   DOI: 10.12337/zgkqzzxzz.2023.04.007
    Abstract469)      PDF (1192KB)(1319)       Save
    Polyetheretherketone (PEEK) is a high-performance specialty plastic with good mechanical properties and biocompatibility and is easy to process and form, making it an alternative material for dental implants. However, the lack of biological activity and the easy accumulation of plaque limit the clinical application of PEEK in the field of oral implantology. At present, many scholars solve the problem of biological inertia and plaque attachment of PEEK through trace elements modification. Different trace elements have their own advantages. Strontium, tantalum, manganese, and other elements can promote osteoblast differentiation. Fluorine, silver, zinc, and other elements can inhibit the growth of inflammatory bacteria, and the co-modification of various trace elements gives PEEK implant more diversified properties.
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    The decision-making principles of sinus floor elevation (part 2)
    Pi Xuemin, Chen Deping, Liu Qian, Ren Bin, Pan Hong, Su Yucheng
    Chinese Journal of Oral Implantology    2022, 27 (6): 387-392.   DOI: 10.12337/zgkqzzxzz.2022.12.011
    Abstract443)      PDF (1289KB)(1281)       Save
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    Research progress of zinc-based biodegradable metals for biological barrier membrane
    Xu Shulan, Chen Jiahao
    Chinese Journal of Oral Implantology    2023, 28 (1): 19-25.   DOI: 10.12337/zgkqzzxzz.2023.02.004
    Abstract723)      PDF (1549KB)(1227)       Save
    Guided Bone Regeneration (GBR) is the most common bone augmentation procedure in implant dentistry, and the effect of bone augmentation is determined by the material properties of the biological barrier membranes. However, are current biological barrier membranes are insufficient for all clinical requirements, including excellent biocompatibility, high mechanical properties, controllable degradation behavior, superior bioactivity, and easy clinical management. It is required to develop and investigate a novel material for the biological barrier membrane. Biodegradable metals (BMs) refer to metals that are intended to degrade in vivo. Among them, zinc(Zn)-based BMs are regarded as a novel generation of biological barrier membrane materials due to their excellent material properties. Nevertheless, Zn-based biological barrier membranes have been still in the stage of research and development. Based on our previous research studies and considering the future clinical applications, this paper systematically reviewed the research status and drawbacks of Zn-based biological barrier membranes in terms of four aspects: biocompatibility, mechanical properties, biodegradability, and bioactivity, providing scientific evidence to promote its clinical transformation.
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    Clinical implications of 3-dimensional osteogenesis model for maxillary sinus to promote osteogenesis in maxillary sinus
    Zhou Yanmin, Qin Qiuyue
    Chinese Journal of Oral Implantology    2023, 28 (2): 69-76.   DOI: 10.12337/zgkqzzxzz.2023.04.001
    Abstract546)      PDF (2718KB)(1214)       Save
    The "3-dimensional osteogenesis model for maxillary sinus" (3D-OMMS) elucidated the osteogenic mechanism of maxillary sinus floor elevation. It provides a scientific theoretical basis for the treatment of maxillary sinus floor elevation in patients with missing maxillary posterior teeth. This manuscript reports the clinical application of "3D-OMMS" in the implants including single tooth or multiple teeth, immediate and delayed implants, transalveolar sinus floor elevation and lateral window approach sinus floor elevation, respectively. Preoperative and postoperative cone-beam computed tomography(CBCT)images were used to evaluate the osteogenic effect of the maxillary sinus region. In conclusion, the application of 3D-OMMS can form a three-dimensional space with diversified osteogenic directions in the maxillary sinus, shorten the vascularization osteogenesis path, accelerate the osteogenic process, improve the quality of new bone, and increase the success rate of implantation, which can be widely used in clinical practice.
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    Expert consensus on bone grafting materials for maxillary sinus floor elevation: bone substitutes
    Chinese Society of Oral Implantology
    Chinese Journal of Oral Implantology    2023, 28 (1): 3-8.   DOI: 10.12337/zgkqzzxzz.2023.02.002
    Abstract976)      PDF (1435KB)(1213)       Save
    Autogenous bone has long been considered the "gold standard" for maxillary sinus floor elevation. However, secondary iatrogenic injury, limited source, easy resorption, and high risk of complications at donor sites limit its clinical application. Thus, the search for and selection of an ideal bone substitute for autologous bone becomes the development trend of bone augmentation technique. In this paper, the characteristics of three major bone substitutes including allograft, xenograft, and alloplastic graft, as well as the implant survival rate after the above bone substitutes were used on the maxillary sinus floor were summarized.
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    Recent progress in bone regenerative materials for implant dentistry
    Li Xin, Liu Kaizheng, Wu Shiyu, Liu Yuanxiang, Huang Baoxin, Qiao Wei, Pan Haobo, Chen Zhuofan
    Chinese Journal of Oral Implantology    2024, 29 (4): 371-377.   DOI: 10.12337/zgkqzzxzz.2024.08.013
    Abstract644)      PDF (1414KB)(1207)       Save
    There has been an increasing number of cases involving bone regeneration in oral clinical treatments, and the requirements for related biomaterials are simultaneously getting higher. This review aims to summarize the research status of bone regeneration materials in the field of implant dentistry. First, specific characteristics of oral bone regeneration applications are introduced. Next, the biochemical and physical properties that affect the performance of materials are discussed, followed by some of the key issues in the field. Finally, an outlook on future research directions is provided to promote the development of next-generation oral bone regeneration materials.
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    Research status on 3D printed individualized scaffold materials in alveolar bone augmentation
    Cheng Yi, Huang Haitao
    Chinese Journal of Oral Implantology    2023, 28 (2): 114-118.   DOI: 10.12337/zgkqzzxzz.2023.04.008
    Abstract482)      PDF (1165KB)(1196)       Save
    Patients with severe bone mass deficiencies require bone augmentation surgery prior to implantation, and the success depends on the stability of the bone graft material and the ability to maintain the bone regeneration space. The scaffolds provide the spatial structure and osteogenic environment for bone regeneration, which are critical to the effect of bone augmentation. With the development of computer-aided design and computer-aided manufacturing, 3D printed individualized scaffolds prepared from different materials have emerged. In this paper, the characteristics and applications of titanium mesh, polyetheretherketone mesh and absorbable polymer composite scaffold materials are discussed, and the application effects and future development directions are evaluated.
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    Clinical analysis of extraction site preservation using Bio-Oss Collagen after extraction of maxillary molars
    Yu Jiuyue, Jia Wenhao, Fang Li, Wang Jian, Li Jiangming, Liu Han, Guo Qili
    Chinese Journal of Oral Implantology    2023, 28 (2): 90-96.   DOI: 10.12337/zgkqzzxzz.2023.04.004
    Abstract598)      PDF (1591KB)(1157)       Save
    Objective To investigate a clinical treatment method for extraction site preservation using Bio-Oss Collagen after extraction of maxillary molars. Methods The clinical data of 6 cases were retrospectively analyzed, and all 6 patients were treated with Bio-Oss Collagen for extraction site preservation after extraction of maxillary molar teeth. These six cases met the following characteristics: the affected tooth was destructed in the alveolar bone in the area of its furcation due to periodontitis or combined periodontal-endodontic lesions, and needed to be extracted; the remaining bone height in the top central part of the alveolar ridge was less than 3.5 mm after the extraction of the affected tooth; the bone walls of the buccal, lingual, mesial and distal parts of the extraction socket were nearly intact. After extraction of the affected tooth, the granulation tissue in the alveolar socket was thoroughly removed. Bio-Oss Collagen was placed in the alveolar sockets and the soft tissues were cross-sutured to hold the graft in place. The sutures are removed 7-10 days after surgery. CBCT was taken preoperatively, immediately postoperatively and at six months postoperatively. The vertical height of the remaining alveolar ridge was measured using Mimics 20.0 at five sites: buccal and lingual in the coronal position, mesial and distal in the median sagittal position, and central. Results Primary healing was obtained in all six patients. At 6 months after extraction, the patients had well healed alveolar sockets, normal gingival color and texture, and no change in attached gingival width. CBCT taken at 6 months after extraction showed no change or a small increase in alveolar crest height at the buccal, lingual, mesial and distal sites, but an increase of 3.48 to 7.89 mm at the central site, among the 5 sites measured. Conclusion After extraction of maxillary molars, Bio-Oss Collagen can be used for extraction site preservation if the surrounding bone wall height is adequate. This method causes less trauma, has a shorter operation time, and its results are similar to those of conventional extraction site preservation.
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    Combined use of computer-assisted dynamic navigation and socket shield technique in immediate implant placement
    Liu Quan, Chen Jieyin, Liu Meixiu, Chen Zhuofan
    Chinese Journal of Oral Implantology    2023, 28 (2): 124-127.   DOI: 10.12337/zgkqzzxzz.2023.04.010
    Abstract357)      PDF (1524KB)(1146)       Save
    The optimal three-dimensional position of dental implants could be obtained by using computer-assisted dynamic navigation based on intraoperative tracking and real-time feedback. The recession of peri-implant soft- and hard tissues can be largely reduced by the socket-shield technique due to the preservation of root segments and periodontal ligaments. Therefore, the combined use of computer-assisted dynamic navigation and socket shield technique in immediate implant placement may be of value to achieve a satisfactory clinical outcome. The aim of this article was to elaborate on the main procedure in the combined use of computer-assisted dynamic navigation and socket shield technique in immediate implant placement.
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    A review of the application of osseointegrated implant removal techniques
    Cai Guoxin
    Chinese Journal of Oral Implantology    2023, 28 (4): 279-284.   DOI: 10.12337/zgkqzzxzz.2023.08.012
    Abstract358)      PDF (1819KB)(1113)       Save
    In this paper, we searched CNKI, Google Scholar, PubMed, Embase and other databases from 2000 to 2022 for all the published literature related to the osseointegrated implant removal techniques, and counted the number of clinical cases of osseointegrated implant removal and the number of implants surgically removed, the location of implants, poor prognosis and other information. The clinical cases and surgical removals of osseointegrated implants were counted, and the numbers of implants, implant locations, and poor prognosis were summarized. The indications for osseointegrated implant removal were summarized, and the limitations and possible complications of various methods were discussed, and a series of decision-making options were proposed to help clinicians to determine the most appropriate minimally invasive technique for removing osseointegrated implants.
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    Application and research progress of customized additive manufactured titanium mesh in bone augmentation for oral implantation
    Wang Lingxu, Wang Fangfang, Wang Penglai
    Chinese Journal of Oral Implantology    2023, 28 (5): 364-370.   DOI: 10.12337/zgkqzzxzz.2023.10.012
    Abstract1077)      PDF (1348KB)(1112)       Save
    Guided bone regeneration (GBR) is a popular method for bone augmentation in oral implant restoration. Titanium mesh has become increasingly prevalent due to its excellent mechanical properties and support fixation. However, traditional prefabricated titanium mesh has limitations, such as poor fitting with the alveolar bone shape, which can result in complications such as wound tearing, mucosal damage, and titanium mesh exposure. Additive manufacturing technology, such as 3D printing, allows for the customization of customized titanium mesh with varying shapes, thicknesses, and porosity. This customized approach not only upholds the excellent mechanical properties and biocompatibility of traditional titanium meshes but also achieves high-precision bone grafting through meticulous preoperative design and digital virtual reconstruction. Such an approach not only streamlines the surgical procedure and shortens surgery time, but also simplifies the surgeon’s operations and reduces trauma to patients. However, in clinical application, even though postoperative complications have decreased, issues such as the exposure of the titanium mesh persist and require careful attention. Despite the considerable clinical potential of titanium mesh from customized manufacturing, in-depth subsequent research is crucial to enhance its effectiveness. This article provides an overview of the current clinical application and research status of customized additive manufactured titanium mesh.
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    The immune microenvironment remodeling of the coagulation-immune complex based on the control of blood clot fibrin network
    Su Mengxi, Wu Shiyu, Shan Zhengjie, Xie Lv, Wu Xiayi, Chen Zetao, Chen Zhuofan
    Chinese Journal of Oral Implantology    2022, 27 (6): 365-370.   DOI: 10.12337/zgkqzzxzz.2022.12.007
    Abstract458)      PDF (1080KB)(1087)       Save
    The immune microenvironment of the early wound is the important stage that influences the outcome of tissue repair and regeneration. There is some overlap between the early immune microenvironment and the blood coagulation process including blood infiltration, clot formation, and its organization, as their biological processes involve many of the same immune cell clusters and cytokines. In recent years, it has been found that the fibrin network in clots can act on immune cells in several ways and be involved in shaping the immune microenvironment. Therefore, it has great significance to reveal the immunoregulatory targets of the clot fibrin network and to elucidate the regulatory laws. To address this coagulation-immune complex, we first clarify the effect of the blood clot and its fibrin network on tissue regeneration, further reveal the biological basis of the fibrin networks involvement in shaping the immune microenvironment, and finally introduce new advances in the regulation of the coagulation-immune complex immune microenvironment based on the fibrous network control. This review aims to provide ideas for the development of a new generation of immune-intelligent regenerative materials.
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    Expert consensus on sinus floor elevation with maxillary sinus cyst or cyst-like lesions
    Chinese Society of Oral Implantology
    Chinese Journal of Oral Implantology    2024, 29 (3): 195-201.   DOI: 10.12337/zgkqzzxzz.2024.06.001
    Abstract754)      PDF (1090KB)(1063)       Save
    Sinus floor elevation is a predictable rehabilitation method commonly used to address bone deficiency in the maxillary posterior area. However, the presence of maxillary sinus cysts often presents a challenge for sinus floor elevation. At present, there is still a lack of guidelines or consensus on sinus floor elevation with maxillary sinus cyst. The purpose of this consensus is to provide clinicians with practical and feasible measures for sinus floor elevation with maxillary sinus cysts.
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    Current status and progress of clinical application of oral occlusion
    Chen Jiang, He Kaixun
    Chinese Journal of Oral Implantology    2024, 29 (1): 3-8.   DOI: 10.12337/zgkqzzxzz.2024.02.002
    Abstract650)      PDF (1322KB)(1059)       Save
    Oral occlusion involves tooth position, temporomandibular joint movement, and muscle function. Normal oral occlusion is crucial for chewing, pronunciation, facial expressions, and other functions. Malocclusion can cause a series of complications, including pain in the temporomandibular joint and chipping of restorations. Therefore, the importance of oral occlusion in the field of oral medicine has become increasingly prominent. Through in-depth research on oral occlusion, dentists can better diagnose and treat occlusion-related problems and improve treatment effects and patients' quality of life. This article intends to introduce the current status and future directions of oral occlusion research and guide the application and development of implant occlusion.
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    Progress in the study of osteogenesis after maxillary sinus floor elevation
    Deng Lei, Huang Haitao
    Chinese Journal of Oral Implantology    2023, 28 (1): 53-57.   DOI: 10.12337/zgkqzzxzz.2023.02.010
    Abstract533)      PDF (1561KB)(1049)       Save
    Maxillary sinus floor elevation is the main technique to address the problem of bone shortage in the maxillary posterior region currently. By creating an osteogenic space in the maxillary sinus floor, bone graft materials can be implanted or not implanted to guide the growth of new bone, thereby increasing the osseointegration of the implant and achieving long-term stability of the implant. Therefore, the research on the source and osteogenic mechanism of new bone after maxillary sinus floor elevation is of great importance for the improvement of clinical surgery and the long-term success of the implant.
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