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Research progress on metal-organic frameworks in dental medicine Li Jian, Liang Ye, Zhao Baodong Chinese Journal of Oral Implantology    2024, 29 (6): 602-609.   DOI: 10.12337/zgkqzzxzz.2024.12.025 Abstract （893）      PDF （1601KB）（2964）       Knowledge map    Save Metal-organic frameworks (MOFs) are nanoporous materials synthesized through the self-assembly of metal nodes and organic ligands. They are characterized by their highly ordered porosity, tunable pore size, large specific surface area, and diverse structures. With the advancements and applications of MOFs in the biomedical field, an increasing number of researchers have introduced MOFs into dental medicine for research. New MOFs have been tailored or developed based on the characteristics of the oral environment and diseases for use in oral disease treatment. The most commonly used MOFs in dentistry primarily include zeolitic imidazolate framework-8 (ZIF-8) and zeolitic imidazolate framework-67 (ZIF-67). The structure and function of MOFs are suitable for treating oral diseases, and they have shown promising results in researches related to periodontal disease, oral and maxillofacial tumors, dental pulp disease, and dental implants. However, their effectiveness still requires further validation through clinical trials. Reference | Related Articles | Metrics

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Influence factors of achieving predictable maxillary sinus bone augmentation Zhao Yang Chinese Journal of Oral Implantology    2024, 29 (3): 289-294.   DOI: 10.12337/zgkqzzxzz.2024.06.016 Abstract （2781）      PDF （1348KB）（2422）       Knowledge map    Save Maxillary sinus floor elevation is a common surgical method to solve the problem of insufficient bone mass in the posterior maxillary region. Based on the special background of maxillary sinus bone augmentation, we explore the principles of achieving predictable maxillary sinus bone augmentation results from the mechanism of osteogenesis, which can be considered from four aspects: bone contact area, angiogenesis, stability of space, and safe healing. Reference | Related Articles | Metrics

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Expert consensus on titanium mesh supported guided bone regeneration Editorial Board of Chinese Journal of Oral Implantology Chinese Journal of Oral Implantology    2024, 29 (2): 95-100.   DOI: 10.12337/zgkqzzxzz.2024.04.001 Abstract （1235）      PDF （1401KB）（2398）       Knowledge map    Save Nowadays, the clinical application of titanium mesh supported guided bone regeneration (TMs-GBR), especially using 3D printing individualized titanium mesh (3D-PITM), is increasing, serving as a reliable solution for bone augmentation in various cases of bone defects, particularly complex ones encountered during implant surgery. Given the technical sensitivity of TMs-GBR and the higher risk of complications such as titanium mesh exposure, as well as the current lack of relevant guidelines or international consensus, the editorial board of the Chinese Journal of Oral Implantology organized discussions among relevant experts and drafted this consensus, aiming to provide clinical reference for practitioners. Reference | Related Articles | Metrics

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Research advances in treatment of tooth agenesis Geng Chenxin, Liu Yang, Han Dong Chinese Journal of Oral Implantology    2024, 29 (3): 224-230.   DOI: 10.12337/zgkqzzxzz.2024.06.006 Abstract （635）      PDF （1368KB）（2203）       Knowledge map    Save Tooth agenesis is the most common dental developmental anomaly in humans, which can cause significant chewing, pronunciation, aesthetic and craniofacial development problems. Due to the unique characteristics of tooth agenesis, its treatment is very time-consuming and costly, imposing huge economic burdens and mental stress on patients. The treatments include a sequential therapeutic strategy with a multidisciplinary team of pediatric dentistry, prosthodontics, oral and maxillofacial surgery, orthodontics, oral implantology, and other backgrounds, as well as emerging methods such as targeted molecular therapy and tissue engineering. This review provides an update on the knowledge on the characteristics of tooth agenesis, traditional treatments, and the rising fields of molecular therapy and tissue engineering. We also discuss the treatment effects of each method, aiming to provide a reference for the treatment of tooth agenesis. Reference | Related Articles | Metrics

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Research progress on medication-related osteonecrosis of the jaw Gao Tingting, Bao Yongjie, Lv Xiaoyan, Chen Xian, Liu Yang, Xu Yilei, Lu Huanyou Chinese Journal of Oral Implantology    2024, 29 (5): 492-497.   DOI: 10.12337/zgkqzzxzz.2024.10.016 Abstract （892）      PDF （1310KB）（1516）       Knowledge map    Save Medication-related osteonecrosis of the jaw (MRONJ) may be induced during the treatment of oral diseases in patients receiving anti-resorptive drugs such as bisphosphonates and denosumab, as well as angiogenesis inhibitors. However, the exact mechanism of MRONJ remains unclear, and although numerous studies have established clinical treatment databases, definitive treatment strategies have yet to be developed. Through a review of the literature, this study discusses the definition, etiology, staging, risk factors, treatment and prevention of MRONJ, providing a reference for clinical practice in oral healthcare. Reference | Related Articles | Metrics

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A systematic literature review on the implant survival rate for congenitally missing teeth Zhao Yu, Zan Bingxin, Dai Qinggang Chinese Journal of Oral Implantology    2024, 29 (3): 242-251.   DOI: 10.12337/zgkqzzxzz.2024.06.009 Abstract （494）      PDF （1424KB）（1507）       Knowledge map    Save Objective To review the relevant literature from the last decade reporting on the outcomes of congenitally edentulous patients after implant prosthetic restoration, and to synthesize the implant survival rates from different perspectives to provide information for clinical decision-making. Methods A search using the combination ("hypodontia" OR "oligodontia" OR "anodontia" OR "tooth agenesis" OR "congenitally missing teeth") AND "dental implant*" was used in databases such as PubMed, with a time frame from February 2014 to February 2024. The literature was screened according to the established inclusion and exclusion criteria, and the bibliographies of the selected research articles were manually searched. Results A total of 34 prospective/retrospective studies and some case reports on implant restorations in congenitally edentulous patients were finally included. It was found that the overall implant survival rate in these patients was high, with an average of 96.53%, depending on individual patient factors and treatment techniques. Congenital edentulism was categorized into simple congenital edentulism and syndromic congenital edentulism, with survival rates of 97.32% and 95.54%, respectively, based on the relationship with systemic diseases. There were slight differences in implant survival rates between different age groups, with 93.82% for patients aged 17 years and younger, and 96.83% for adult patients aged 18 years and older. The maxillary lateral incisors, with a high rate of congenital defects involving the anterior esthetic zone, had an ideal implant survival rate (98.48%). The implant survival rate for congenitally edentulous patients combined with bone augmentation techniques was 96.19%. The survival rates for zygomatic implants and small-diameter implants (or mini-implants) were 98.18% and 97.18%, respectively. Conclusion Implant surgery is a better solution to restoring oral function in congenitally edentulous patients. However, it still needs to be analyzed according to the patient's situation to improve the implant survival rates and the success of implant restoration. Reference | Related Articles | Metrics

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Recent progress in bone regenerative materials for implant dentistry Li Xin, Liu Kaizheng, Wu Shiyu, Liu Yuanxiang, Huang Baoxin, Qiao Wei, Pan Haobo, Chen Zhuofan Chinese Journal of Oral Implantology    2024, 29 (4): 371-377.   DOI: 10.12337/zgkqzzxzz.2024.08.013 Abstract （767）      PDF （1414KB）（1485）       Knowledge map    Save There has been an increasing number of cases involving bone regeneration in oral clinical treatments, and the requirements for related biomaterials are simultaneously getting higher. This review aims to summarize the research status of bone regeneration materials in the field of implant dentistry. First, specific characteristics of oral bone regeneration applications are introduced. Next, the biochemical and physical properties that affect the performance of materials are discussed, followed by some of the key issues in the field. Finally, an outlook on future research directions is provided to promote the development of next-generation oral bone regeneration materials. Reference | Related Articles | Metrics

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The characteristics of nisin and its application in peri-implantitis: a review of recent research Wang Yu Chinese Journal of Oral Implantology    2025, 30 (1): 86-90.   DOI: 10.12337/zgkqzzxzz.2025.02.015 Abstract （383）      PDF （1723KB）（1470）       Knowledge map    Save Peri-implantitis is one of the main causes of implants failure. Nisin is a bacteriocin produced by Lactobacillus, which exerts bacteriostatic effects by forming pores in bacterial cell membranes. Nisin has been shown to effectively inhibit the pathogenic bacteria associated with peri-implantitis, demonstrating its potential for use in the treatment of this condition. This review article discusses the characteristics of nisin and the research progress on its application in peri-implantitis. Reference | Related Articles | Metrics

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Risk factor analysis and treatment strategies for oral implant restoration in patients with Sjögren syndrome Chen Li, Fang Ming, Zhang Yanting, Zhang Xiaolin, Liu Qing, Zheng Zhaohui, Zhou Wei Chinese Journal of Oral Implantology    2024, 29 (4): 320-327.   DOI: 10.12337/zgkqzzxzz.2024.08.005 Abstract （483）      PDF （2288KB）（1458）       Knowledge map    Save Sjögren syndrome (SS) is a common disease in oral clinical practice with typical symptoms such as dry mouth and dry eyes, often accompanied by complex systemic symptoms and a long history of medication. With the growing prevalence of dental implant restorations, there has been a corresponding rise in the demand for implantation treatments among individuals with Sjögren Syndrome. However, there is a lack of relevant treatment guidelines for implant restoration in these patients. This article presents a case of an implant-supported fixed complete dental prosthesis in a patient with Sjögren syndrome,summarizes our team's experience in the treatment of implant restoration in these patients, and discusses the risk assessment and treatment strategies for dental implant restorations in patients with Sjögren syndrome. A comprehensive risk assessment before treatment, a reasonable implant restoration plan, and consistent long-term plaque control are essential for the successful outcomes of implant restorations in patients with Sjögren syndrome. Reference | Related Articles | Metrics

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Current research status of transalveolar technique for sinus floor elevation with simultaneous placement of dental implants Xia Haibin, Xu Junyi Chinese Journal of Oral Implantology    2024, 29 (2): 109-117.   DOI: 10.12337/zgkqzzxzz.2024.04.004 Abstract （757）      PDF （1604KB）（1444）       Knowledge map    Save When the residual bone height is insufficient in the maxillary posterior region, the transalveolar technique for sinus floor elevation with simultaneous implant placement is less invasive, resulting in milder postoperative reactions and shorter treatment periods compared to the lateral window technique. However, due to the limited surgical vision and elevation technique, the transalveolar technique is susceptible to mucoperiosteal perforation or compromised osteogenesis and is therefore traditionally considered suitable only for cases where the residual bone height is mildly inadequate. With modifications to surgical instruments, improvements in clinical skills, and the assistance of digital technology, researchers have gained new insights into the indications and surgical protocols for transalveolar sinus floor elevation with simultaneous placement of dental implants. This paper presents an overview of the current basic and clinical research status of the transalveolar technique for sinus floor elevation with simultaneous implantation by reviewing recent literature. Reference | Related Articles | Metrics

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Application of a new Tent-Peg technique in the reconstruction of severe alveolar bone defects Wang Mohan, Hu Yinghan, Wu Jing, Zou Duohong Chinese Journal of Oral Implantology    2024, 29 (5): 459-466.   DOI: 10.12337/zgkqzzxzz.2024.10.011 Abstract （1311）      PDF （1768KB）（1371）       Knowledge map    Save Adequate bone volume is crucial for the successful placement and long-term stability of dental implants. Therefore, the reconstruction of severe alveolar bone defects hold significant clinical importance. With the development of guided bone regeneration (GBR) techniques, various GBR approaches have been applied in clinical practice to address alveolar bone defects. Based on the concept of "stability-centered" alveolar bone reconstruction, we developed a series of Tent-Peg medical products and established a new Tent-Peg technique. This technique enables the reconstruction of severe alveolar bone defects without the need for autologous bone, providing a novel solution for both the functional and aesthetic reconstruction of such defects. This innovative method has been successfully validated in clinical practice, and its appeal lies in its "three lows" (low technical sensitivity, low failure rate, and low cost) and "three easies" (easy to operate, promote, and popularize). To enhance clinicians' understanding of this innovative technique, this paper provides a comprehensive overview of the Tent-Peg medical product series and highlights the advantages of the new Tent-Peg technique, supported by clinical case demonstrations. This overview aims to promote the standardized application of this technique in clinical practice. Reference | Related Articles | Metrics

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A case of digitally assisted immediate implant placement through impacted teeth in the aesthetic area Zhao Ning, Li Xiaojie, Kou Ni, Ma Guowu Chinese Journal of Oral Implantology    2024, 29 (3): 266-271.   DOI: 10.12337/zgkqzzxzz.2024.06.012 Abstract （925）      PDF （2405KB）（1370）       Knowledge map    Save This paper presents a case of digitally assisted immediate implantation through impacted teeth in the aesthetic area. The patient had a root fracture caused by an upper anterior teeth trauma. One impacted canine and two impacted supernumerary teeth were found in the bone on the root side of the affected teeth. During treatment, under the guidance of the digital surgical guide plate and assistance by Er : YAG laser, immediate implantation through the impacted teeth was achieved. At the same time, autologous bone grafting material and platelet-rich fibrin were mixed for bone grafting at the two implant sites. Provisional and permanent restorations were completed with digital technology at 5 months and 8 months after the first stage of surgery, respectively. Postoperative CBCT showed that the implants penetrated through the crown, apical cementum, dentin, and pulp of the impacted teeth. No pain or other complications were found during the follow-up visit. There were no clinical symptoms at the 18-month follow-up visit. CBCT images showed that the bone density around the implants had increased and the lamina dura had formed. In this case, immediate implantation through the impacted teeth in the aesthetic area was realized with the digital assistance, providing a new clinical idea for the selection of treatment options for impacted teeth and increased clinical data for other healing forms of implants besides osseointegration. However, the clinical effect of this kind of operation still needs long-term follow-up observation. Reference | Related Articles | Metrics

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Management of vertical bone deficiency in the posterior mandibular region Qiu Lixin, Niu Lixuan Chinese Journal of Oral Implantology    2024, 29 (5): 400-406.   DOI: 10.12337/zgkqzzxzz.2024.10.002 Abstract （612）      PDF （1444KB）（1357）       Knowledge map    Save Vertical bone augmentation in the posterior mandibular region is technically demanding and prone to frequent complications. There is no consensus, either domestically or internationally, on the optimal technique. Furthermore, there is a lack of large-scale, high-quality clinical studies on the long-term outcomes of vertical bone augmentation followed by implant-supported restorations. This article provides a systematic review of complications and long-term outcomes of various vertical bone augmentation techniques, drawing on the authors' clinical expertise to provide information on decision-making. Reference | Related Articles | Metrics

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Strategies for implant surface decontamination in therapy of peri-implantitis Yang Ting, Hu Wenjie Chinese Journal of Oral Implantology    2024, 29 (4): 385-390.   DOI: 10.12337/zgkqzzxzz.2024.08.015 Abstract （443）      PDF （1381KB）（1310）       Knowledge map    Save Peri-implantitis is a biofilm-mediated pathological condition of peri-implant tissue, characterized by inflammation in peri-implant mucosa accompanied by progressive loss of supporting bone around dental implants. It is the main reason that affects the long-term result of dental implant restoration, which might eventually lead to implant failure. Implant surface decontamination is the key to the management of peri-implantitis. Non-surgical treatment and surgical treatment have both been used in clinical practice, but there is no gold standard protocol for implant decontamination. Therefore, it is of great significance to compare the characteristics of implants with and without peri-implantitis to understand the decontamination strategy for infected implant surfaces, which can provide a reference for clinicians in the decision-making when managing peri-implantitis. Reference | Related Articles | Metrics

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Simultaneous management of maxillary sinus cysts during sinus floor elevation Bao Yuejie, Zhan Pingping, Lin Zhihao, He Gang Chinese Journal of Oral Implantology    2024, 29 (6): 543-548.   DOI: 10.12337/zgkqzzxzz.2024.12.013 Abstract （524）      PDF （2026KB）（1302）       Knowledge map    Save This article introduces a surgical approach for the simultaneous management of maxillary sinus cysts and sinus floor elevation using the double-window technique. The first lateral window is created to elevate the Schneiderian membrane and establish space for bone augmentation. Once the membrane is fully elevated and remains intact, a second small lateral window is created above the first to remove the cyst. The two windows are separated to prevent contamination of the graft material by the cystic contents. Additionally, a conservative surgical approach for the palliative treatment of sinus cysts is presented. Three representative cases are described to demonstrate specific techniques and surgical methods. Reference | Related Articles | Metrics

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Application of injectable hydrogels in bone tissue regeneration Yang Yupu, Dong Zheqin, Yu Hongwei, Liu Yu, Wang Xiaohong, Wang Shengmiao, Lan Jing Chinese Journal of Oral Implantology    2025, 30 (4): 412-420.   DOI: 10.12337/zgkqzzxzz.2025.08.014 Abstract （217）      PDF （1329KB）（1292）       Knowledge map    Save With the development of bone tissue engineering technologies, novel biomaterials have gradually become a major research focus in the field of modern bone tissue repair. Injectable hydrogels, due to their excellent biocompatibility, high tunability, and drug-loading capacity, have increasingly emerged as important materials in bone tissue regeneration. This review summarizes the research progress on injectable hydrogels in bone tissue repair, with a particular focus on their application strategies in the field of bone tissue regeneration. Reference | Related Articles | Metrics

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Expert consensus on sinus floor elevation with maxillary sinus cyst or cyst-like lesions Chinese Society of Oral Implantology Chinese Journal of Oral Implantology    2024, 29 (3): 195-201.   DOI: 10.12337/zgkqzzxzz.2024.06.001 Abstract （911）      PDF （1090KB）（1270）       Knowledge map    Save Sinus floor elevation is a predictable rehabilitation method commonly used to address bone deficiency in the maxillary posterior area. However, the presence of maxillary sinus cysts often presents a challenge for sinus floor elevation. At present, there is still a lack of guidelines or consensus on sinus floor elevation with maxillary sinus cyst. The purpose of this consensus is to provide clinicians with practical and feasible measures for sinus floor elevation with maxillary sinus cysts. Reference | Related Articles | Metrics

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Expert consensus on maxillary sinus floor elevation: maxillary sinus septum Chinese Society of Oral Implantology Chinese Journal of Oral Implantology    2024, 29 (2): 103-108.   DOI: 10.12337/zgkqzzxzz.2024.04.003 Abstract （739）      PDF （1040KB）（1209）       Knowledge map    Save The maxillary sinus septum is a common bony structure in the maxillary sinus. It is very important to understand the presence of the maxillary sinus septum when designing the sinus floor elevation. Therefore, this paper summarizes the classification of maxillary sinus septum, its anatomical and biological characteristics, its influence on maxillary sinus osteogenesis, and its treatment methods and principles, in order to provide a reference for the clinical implementation of sinus floor elevation with maxillary sinus septum, and to reduce the complications caused by the presence of maxillary sinus septum. Reference | Related Articles | Metrics

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Feasibility study of artificial intelligence in immediate implant measurements and analysis in the mandibular molar region Zhao Wenbo, Li Xinru, Su Hang, Teng Weiwei, Cai Wenyu, Zhou Libo Chinese Journal of Oral Implantology    2024, 29 (2): 178-183.   DOI: 10.12337/zgkqzzxzz.2024.04.013 Abstract （411）      PDF （1391KB）（1201）       Knowledge map    Save Objective To analyze and validate the feasibility of an artificial intelligence software, ITK-SNAP, in identifying the distance between mandibular molars and the inferior alveolar nerve canal. Methods The cone-beam CT (CBCT) image data of 100 college students were selected, and 30 cases were randomly selected as the experimental group, and the remaining 70 cases were used as the validation group together with the 30 cases in the experimental group. The distances from the apices of the mandibular molar roots and the tops of the alveolar septa to the inferior alveolar nerve canals were measured using CBCT image analysis software and ITK-SNAP, respectively. Results The differences in the distances between mandibular molars and the inferior alveolar nerve canals measured by CBCT and ITK-SNAP software were not statistically significant in intergroup comparisons ( P>0.05), and had a high correlation with r>0 (correlation coefficients r were all greater than 0.9); in both males and females, the distances from the mesial apices, the distal apices, and the tops of the alveolar septa to the upper walls of the inferior alveolar nerve canals of the mandibular first molars were significantly greater than those of the second molars ( P<0.05), and the distances from each point of the mandibular first molars to the upper walls of the inferior alveolar nerve canals were significantly greater than those of the second molars in both the right and left sides ( P<0.05). Conclusion The artificial intelligence software ITK-SNAP for measuring the distance between mandibular molars and the mandibular canal is feasible, which provides a reference for the preoperative planning of immediate implant placement in the mandibular molar region. Reference | Related Articles | Metrics

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Application and research progress of digital technology in bone augmentation for dental implants Chen Jiang, Qiu Yubei Chinese Journal of Oral Implantology    2024, 29 (3): 252-257.   DOI: 10.12337/zgkqzzxzz.2024.06.010 Abstract （939）      PDF （1333KB）（1195）       Knowledge map    Save Insufficient alveolar bone mass at the implant site is an important factor affecting the outcome of dental implants. Bone augmentation is an effective strategy to solve this problem. The application of digital technology provides a new approach for bone augmentation in oral implantology. This article presents the application and research progress of digital technology in bone augmentation for dental implants. Reference | Related Articles | Metrics

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Research progress and clinical application of dental implant macro-design Cai Wenyu, Ma Junchi, Zhao Wenbo, Wang Yiming, Zhou Libo Chinese Journal of Oral Implantology    2025, 30 (2): 180-186.   DOI: 10.12337/zgkqzzxzz.2025.04.013 Abstract （515）      PDF （1295KB）（1170）       Knowledge map    Save In recent years, the design of implant configurations has been continuously optimized, playing a key role in improving initial stability and promoting osseointegration, which are key factors for achieving long-term functional stability of implants. However, there is still no unified consensus on the optimal implant configuration. This article explores various aspects of implant design, including the neck structure, thread pattern, overall shape, apex features, diameter, and length, with different bone qualities and clinical conditions, such as immediate and delayed implantation, as well as anterior and posterior implantation sites. By summarizing the most favorable implant configurations identified in current research, this review aims to provide a reference for clinical applications. Reference | Related Articles | Metrics

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Effect of different sandblasting parameters on the surface roughness of medical-grade Grade 4 pure titanium Liu Qiqi, Zhao Yujia, Qiu Lin, Hao Junjiang, Su Hanqi, Han Zekui, Wang Xinyu, Su Yucheng Chinese Journal of Oral Implantology    2024, 29 (6): 555-560.   DOI: 10.12337/zgkqzzxzz.2024.12.015 Abstract （342）      PDF （1786KB）（1167）       Knowledge map    Save Objective This study investigates the effect of different sandblasting parameters on the surface roughness of medical-grade Grade 4 pure titanium, aiming to provide reference data for optimizing SLA(sandblasted, large-grit, acid-etched) surface characteristics. Methods Alumina particles were used in an orthogonal experimental design to analyze the effects of particle size, pressure, distance, and time on the surface roughness average (Ra) of Grade 4 pure titanium. Range analysis and variance analysis were performed to evaluate the impact of each parameter. Results The surface roughness with Ra value of 1.083~2.494 μm can be obtained within the range of factor levels in this experiment. The lowest surface roughness (Group A) was achieved with 100-mesh particles, 0.2 MPa pressure, a distance of 50 mm, and a duration of 60 seconds. The highest surface roughness (Group B) was observed with 60-mesh particles, 0.4 MPa pressure, a distance of 100 mm, and a duration of 15 seconds. Conclusion Within the range of parameter levels examined in this study, surface roughness decreased with increasing particles size and blasting time, while it increased with higher pressure and longer blasting distance. Reference | Related Articles | Metrics

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Research progress on digital methods for recording and transferring maxillomandibular relationship Man Yi, Lan Dongping Chinese Journal of Oral Implantology    2024, 29 (3): 212-217.   DOI: 10.12337/zgkqzzxzz.2024.06.004 Abstract （734）      PDF （768KB）（1135）       Knowledge map    Save In recent years, the advancing development of digital dental technology has heralded a new era in full-arch implant restoration. A crucial element for successful complete denture is the accurate recording and transfer of the maxillomandibular relationship. Compared to traditional methods, digital technology has the potential to shorten the treatment cycle and improve the efficiency of diagnosis and treatment. This article elaborates on the application and advances of digital technology in recording and transferring the maxillomandibular relationship in edentulous patients. The opportunities and challenges presented by the digitization of dental technology to clinicians will be discussed, with the aim of providing them with a valuable reference. Reference | Related Articles | Metrics

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Impact of osteoporosis on dental implantation and related clinical considerations Qiu Yun, Wang Yulan, Zhang Yufeng Chinese Journal of Oral Implantology    2024, 29 (4): 336-341.   DOI: 10.12337/zgkqzzxzz.2024.08.007 Abstract （951）      PDF （1397KB）（1098）       Knowledge map    Save With the development of dental technology, dental implants are gradually becoming the primary choice for restoring missing teeth. The quality and quantity of the alveolar bone are key to the success of implant surgery and the long-term retention of the implants. Osteoporosis is a systemic disease characterized by a decrease in bone mass and a reduction in bone density, affecting bones throughout the body, including the alveolar bone. Therefore, its characteristic oral manifestations can be indicative of an early diagnosis of osteoporosis. At the same time, the changes in bone density and bone structure in osteoporosis patients necessitate awareness of the treatment risks during implantation and modification of the treatment plan to improve the success rate of implant treatment. This article reviews the oral manifestations of osteoporosis, the risks of implant treatment, and the consideration for implant treatment through a literature review. Reference | Related Articles | Metrics

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Research progress on the effect of Schneider membrane thickening on transalveolar sinus floor elevation Li Xiaoyu, Yu Huan, Meng Weiyan Chinese Journal of Oral Implantology    2024, 29 (2): 127-132.   DOI: 10.12337/zgkqzzxzz.2024.04.006 Abstract （398）      PDF （1345KB）（1079）       Knowledge map    Save Transalveolar sinus floor elevation is recognized as a minimally invasive and reliable bone augmentation surgery for the posterior maxillary region in implant clinical practice. However, the therapeutic effect remains uncertain when there is Schneider membrane thickening in the maxillary sinus. Given that Schneider membrane thickening is the most common lesion in the maxillary sinus, it is of great clinical significance to clarify its impact on the prognosis of transalveolar sinus floor elevation. In response to this clinical issue, this article provides a review of three aspects: the characteristics of normal Schneider membrane, the manifestations and causes of Schneider membrane thickening, and the impact of Schneider membrane thickening on transalveolar sinus floor elevation, to provide a theoretical basis for the preoperative evaluation of the transalveolar sinus floor elevation. Reference | Related Articles | Metrics

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Research progress on peri-implant soft tissue augmentation materials Chen Jiaxin, Gu Xinhua Chinese Journal of Oral Implantology    2024, 29 (3): 284-288.   DOI: 10.12337/zgkqzzxzz.2024.06.015 Abstract （702）      PDF （1341KB）（1062）       Knowledge map    Save With the increasing maturity of dental implant technology, the aesthetic effects of dental implants and long-term health of surrounding tissues in implant restorations are of growing concern. Due to the decrease in the amount of soft and hard tissue around the missing tooth area, dental defects often fail to meet the requirements for implant restoration. Therefore, the augmentation of soft and hard tissue around the implant is a key step in dental implantation. The purpose of this paper is to introduce common peri-implant soft tissue augmentation materials and provide references to solving the problem of peri-implant soft tissue insufficiency. Reference | Related Articles | Metrics

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Research progress on the influence of depression on peri-implant health Zhao Xintong, Meng Weiyan Chinese Journal of Oral Implantology    2024, 29 (4): 342-346.   DOI: 10.12337/zgkqzzxzz.2024.08.008 Abstract （481）      PDF （1376KB）（1052）       Knowledge map    Save In recent years, implant-supported prostheses have become an important method for repairing missing teeth. However, the long-term survival rate of implants is affected by various systemic and local factors. Depression is a common mental disease with a high prevalence rate, which affects the healing process of soft and hard tissues after implant surgery. Moreover, depression often leads to oral dysbiosis, which can easily promote the occurrence and development of peri-implantitis and affect the long-term efficacy of implants. Antidepressants, such as SSRIs, also affect osseointegration. This article aims to review the effects of depression on the healing process of soft and hard tissues, bone metabolism, and oral microbiome after implantation, hoping to provide a clinical basis for the risk assessment and treatment strategy of implant treatment for patients with depression. Reference | Related Articles | Metrics

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Advances in barrier membranes for guided bone regeneration in oral applications Li Guangda, Ding Mingchao, Chang Xin, Jing Boya, Wang Jingfu, Wang Weiqi Chinese Journal of Oral Implantology    2025, 30 (3): 288-295.   DOI: 10.12337/zgkqzzxzz.2025.06.014 Abstract （343）      PDF （1397KB）（1049）       Knowledge map    Save Guided bone regeneration (GBR) has become a standard clinical approach for the treatment of localized jawbone defects. In this process, barrier membranes play an important role by preventing the migration of soft tissue from the mucosal side into the bone defect area, thereby maintaining a secluded space for bone regeneration. The biological properties and clinical performance of different membranes vary depending on their origin, fabrication methods, and structural characteristics. This paper summarizes the biological functions and mechanisms of commonly used barrier membranes in GBR, with a particular focus on the properties of different membrane types. The advantages and limitations of these biomaterials are discussed, along with their clinical applications and potential directions for future material development. Reference | Related Articles | Metrics

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Application of probiotics in the management of peri-implant diseases Li Meiqi, Sun Xiaolin, Wang Lin Chinese Journal of Oral Implantology    2025, 30 (1): 91-96.   DOI: 10.12337/zgkqzzxzz.2025.02.016 Abstract （301）      PDF （1434KB）（1045）       Knowledge map    Save Peri-implant diseases are chronic inflammatory conditions caused by microbial dysbiosis, primarily manifesting as soft tissue inflammation and supporting bone destruction, which can lead to implant loss. Due to their high prevalence and complex etiology, these diseases have emerged as significant public health concerns. Current treatments mainly rely on traditional methods such as mechanical debridement and antibiotic therapy; however, these approaches have notable limitations. In recent years, probiotics have garnered attention as an emerging biological therapy due to their potential to regulate the microbiome and immune response, showing promise in the prevention and treatment of peri-implant diseases. This review provides an overview of the current applications of probiotics in peri-implant diseases, analyzes their mechanisms of action, and summarizes existing clinical research findings. The goal is to provide new insights for improving treatment outcomes in peri-implant diseases, ultimately aiming to offer patients a more comprehensive oral health management strategy. Reference | Related Articles | Metrics

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The impact of diabetes on the soft tissue seal surrounding dental implants Wang Qian, Yuan Quan Chinese Journal of Oral Implantology    2024, 29 (4): 347-351.   DOI: 10.12337/zgkqzzxzz.2024.08.009 Abstract （667）      PDF （1377KB）（1038）       Knowledge map    Save The soft tissue seal around the dental implants is recognized as a primary mucosal barrier against external stimuli and is critical for maintaining implant stability. Diabetes mellitus (DM) is a known risk factor for peri-implantitis. Persistent hyperglycemia can impair the barrier function of peri-implant soft tissues, leading to peri-implant diseases. Moreover, increased pathogenic bacterial infections, excessive inflammatory cytokine activity, and impaired wound healing in diabetic conditions may result in poor soft tissue sealing around implants. This review outlines the structure of peri-implant soft tissue sealing, explores the factors contributing to impaired soft tissue sealing in diabetes, and summarizes methods to improve the mucosal barrier in diabetic patients, providing guidance for implant treatment strategies in diabetic patients. Reference | Related Articles | Metrics

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Research on the utilization of sticky bone in bone regeneration Liang Yixin, Qu Zhe Chinese Journal of Oral Implantology    2025, 30 (2): 111-117.   DOI: 10.12337/zgkqzzxzz.2025.04.004 Abstract （361）      PDF （1622KB）（1007）       Knowledge map    Save The high concentrations of growth factors within platelets have been proven to promote cell migration, proliferation, and angiogenesis during the regeneration process. Multiple efforts have been exerted to blend them with bone substitute materials, to fabricate "sticky bone" for easier manipulation by surgeons. While autologous and allogeneic bone grafts are limited by donor site availability and biocompatibility issues, synthetic bone grafts exhibit significant advantages in terms of biocompatibility. The integration of growth factors into these porous synthetic grafts can effectively stimulate cell growth and differentiation, thereby enhancing osteogenic potential. This paper reviews the research and advancements in sticky bone for bone regeneration, elaborating on the fabrication and characterization of sticky bone materials. Moreover, it also highlights the promising outcomes and benefits of sticky bone in bone defect regeneration, substantiated by clinical data from both domestic and international studies. Reference | Related Articles | Metrics

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Current research status of implant intervention in adolescents with severe tooth loss due to ectodermal dysplasia Su Guanyu, Shen Yihan, Wu Yiqun, Wang Feng Chinese Journal of Oral Implantology    2024, 29 (3): 236-241.   DOI: 10.12337/zgkqzzxzz.2024.06.008 Abstract （476）      PDF （1434KB）（995）       Knowledge map    Save Tooth agenesis is a typical developmental abnormality in the oral and maxillofacial region among teenagers. Ectodermal dysplasia(ED) is the primary cause of severe tooth agenesis in adolescents. Teenagers with severe tooth agenesis benefit from implant intervention for the possibility of regaining masticatory function and speech function, as well as maintaining a pleasing facial appearance. In terms of retention and stability, implant-supported dentures for teenagers outperform conventional removable dentures. This review elaborates on the feasibility of implant placement in teenagers with ED, focusing on the considerations of implant placement and common methods for this special group of patients. Lastly, prospects for further study in this field are highlighted. Reference | Related Articles | Metrics

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Research progress in the construction of murine experimental model of peri-implantitis Sun Yuxin, Shi Bin, Wu Tao Chinese Journal of Oral Implantology    2025, 30 (3): 281-287.   DOI: 10.12337/zgkqzzxzz.2025.06.013 Abstract （214）      PDF （1369KB）（981）       Knowledge map    Save Peri-implantitis is one of the most intractable complications in dental implant treatment, which is also the key factor for implant failure. The construction of relevant animal experimental models that can accurately simulate the pathological features of peri-implantitis is crucial for in-depth exploration of its pathogenesis. This review systematically collates the research progress in recent years on the establishment of murine experimental models of peri-implantitis. The content encompasses the scientific selection of experimental animals, the application of innovative modeling methods, modeling time, the accurate evaluation of modeling outcome indicators, and an in-depth analysis of key factors such as success rate. The aim is to provide more comprehensive and accurate references for researchers in this field. Reference | Related Articles | Metrics

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Causes, prevention and treatment of titanium mesh exposure after 3D printing individualized titanium mesh supported guided bone regeneration Su Yucheng, Ren Bin Chinese Journal of Oral Implantology    2025, 30 (1): 5-12.   DOI: 10.12337/zgkqzzxzz.2025.02.003 Abstract （644）      PDF （1665KB）（957）       Knowledge map    Save 3D printing individualized titanium mesh serves as a space maintenance device, effectively creating and maintaining osteogenic space, reducing intraoperative time and the difficulty of surgery. It is a reliable bone augmentation solution for various types of alveolar ridge bone defects. However, during clinical application, postoperative titanium mesh exposure is the most common complication and requires clinicians' attention. This article elaborates on the causes, prevention, and treatment of postoperative titanium mesh exposure in guided bone regeneration supported by 3D-PITM, with the aim of providing clinical reference. Reference | Related Articles | Metrics

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Application of Bloom’s Taxonomy in the standardized residency training program for implant dentistry Li Fulong, Deng Yu, Tian Sirui, Gao Jing, Zhao Baohong Chinese Journal of Oral Implantology    2024, 29 (6): 610-615.   DOI: 10.12337/zgkqzzxzz.2024.12.026 Abstract （325）      PDF （1783KB）（950）       Knowledge map    Save Objective To investigate the effectiveness of applying Bloom’s Taxonomy in the standardized training of oral implantology residents and evaluate its impact on the knowledge, skills, and clinical practice abilities of the trainees. Methods A total of 33 residents who completed a clinical rotation in the oral implantology department from January to July 2023 were selected as the control group (traditional teaching mode), while 31 residents who rotated in the same department from January to July 2024 were selected as the experimental group (Bloom's Taxonomy-based teaching). Data were collected one month before the completion of the training program, including knowledge tests, skill assessments, and evaluations of clinical performance, to assess the teaching effectiveness of both approaches. Results Residents trained with Bloom’s Taxonomy demonstrated significant improvements in both theoretical assessments and practical skill operations. The experimental group showed a notable increase in theoretical knowledge (control group score: 34.97±3.26, experimental group score: 42.32±3.42, P<0.001) and enhanced ability to apply clinical case analysis (control group score: 39.24±2.56, experimental group score: 43.03±2.36, P<0.001). Moreover, the experimental group performed better in medical history collection, clinical examination, treatment planning, medical record documentation, and procedural skills (control group total score: 74.13±5.08, experimental group total score: 80.77±6.10, P<0.001). Conclusion The application of Bloom's Taxonomy positively enhances the standardized training of implant dentistry. Reference | Related Articles | Metrics

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Meta-analysis of the accuracy of dental implant robots in preclinical and clinical studies Wang Yiming, Li Xinru, Teng Weiwei, Ma Junchi, Zhou Libo Chinese Journal of Oral Implantology    2024, 29 (4): 362-370.   DOI: 10.12337/zgkqzzxzz.2024.08.012 Abstract （459）      PDF （2393KB）（941）       Knowledge map    Save Objective To systematically evaluate the accuracy of dental implant surgery assisted by a dental implant robot system in both preclinical and clinical studies. Methods Studies of dental implant robots were searched on online platforms like PubMed, Cochrane Library, Web of Science, Embase, CNKI, CQVIP, and Wanfang data from the establishment of the database to August 2023. The studies included preclinical (model and animal experiments) and clinical research. The main outcome measures were three-dimensional deviations between the targeted position and the implanted position, including the coronal deviation, apical deviation, and angular deviation of implants. Stata 14.0 and RevMan software were used for meta-analysis of the data. Subgroup analysis was used to compare errors in four aspects: different study designs and subjects, preparation of implant cavities versus insertion of implants, dentition condition, and specific anatomical structures. Results Finally, 23 studies (18 preclinical studies and 5 clinical studies) from 20 papers were included, comprising a total of 840 implant sites. The results of the meta-analysis showed that in the preclinical study of dental implant robot-assisted implantation, the coronal deviation, apical deviation, and angular deviation were 0.60 mm (95% CI: 0.51~0.70, I2=0.0%), 0.73 mm (95% CI: 0.62~0.84, I2=24.9%), and 1.25°(95% CI: 1.02~1.48, I2 = 47.9%), respectively. In clinical studies, the coronal deviation, apical deviation, and angular deviation were 0.62 mm (95% CI: 0.39~0.86, I2=0.0%), 0.63 mm (95% CI: 0.39~0.87, I2=0%) and 1.23°(95% CI: 0.71~1.76, I2=15.9%), respectively. Conclusion There was no statistical difference in the coronal deviation, apical deviation, and angular deviation of dental implant surgery assisted by the dental implant robot system in preclinical and clinical studies, providing a reference for subsequent experiments and clinical applications. Reference | Related Articles | Metrics

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Risks and countermeasures of dental implant treatment in osteoporosis patients Liu Zhonghao, Dong Kai Chinese Journal of Oral Implantology    2024, 29 (4): 303-310.   DOI: 10.12337/zgkqzzxzz.2024.08.003 Abstract （812）      PDF （1557KB）（934）       Knowledge map    Save Osteoporosis (OP) is a systemic skeletal disease with the main characteristic of reduction of bone density and low bone mass. With the increasing age of the population, the incidence of OP increases year by year. Replacement of missing teeth with dental implants is one of the most common treatment options with a high success rate. However, in patients with OP, deterioration of bone tissue may lead to an increased risk of implant failure. Although OP is not a contraindication for implant therapy, clinicians should still pay great attention to associated risk factors. This article discusses the alveolar bone modeling and remodeling, the success rates of dental implants, the influence of anti-osteoporosis drugs, and the strategy of dental implant treatment in OP patients for clinical reference. Reference | Related Articles | Metrics

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"Improved" maxillary sinus lift surgery Sun Xiaolin, Luo Jiaxin Chinese Journal of Oral Implantology    2024, 29 (2): 118-126.   DOI: 10.12337/zgkqzzxzz.2024.04.005 Abstract （573）      PDF （1637KB）（930）       Knowledge map    Save When posterior maxillary teeth are missing, the residual bone height required for implantation is insufficient due to the lack of functional stimulation from the teeth and pneumatization of the maxillary sinus. When residual bone volume cannot ensure the initial stability of the implant, a maxillary sinus floor elevation is needed to increase bone volume in the posterior maxillary region. The "PESS" procedure is a "modified" maxillary sinus floor elevation surgery that uses platelet-rich fibrin (PRF) as a single bone graft material, with the aid of an endoscope to elevate the maxillary sinus floor through the alveolar ridge and place implants simultaneously. The PESS procedure has optimized maxillary sinus floor elevation surgery to some extent and reduced surgical trauma. This article elaborates on the principles, indications, clinical procedures, and precautions of the "PESS" procedure to provide technical support for its clinical application. Reference | Related Articles | Metrics

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Advances of yttrium-containing zirconia materials in dental clinical applications Xie Hailin, Guo Xueqi, Wang Liping Chinese Journal of Oral Implantology    2024, 29 (2): 184-189.   DOI: 10.12337/zgkqzzxzz.2024.04.014 Abstract （799）      PDF （1344KB）（929）       Knowledge map    Save Yttrium-containing zirconia ceramic (YCZC) has been widely used in field of implant and restorative dentistry. It has good mechanical and biological properties when compared with other types of zirconia ceramics. Different types of zirconia ceramics have been used in clinical application, such as Yttrium-stabilized tetragonal zirconia polycrystal (Y-TZP)with high mechanical properties, and Yttrium-partially stabilized zirconia (Y-PSZ)with high aesthetic properties. Therefore, understanding the physical and chemical properties of different YCZC can improve the clinical success of dental restorations. This article summarizes the available literature concerning the physical and chemical properties of YCZC and their clinical applications in the field of dentistry. Reference | Related Articles | Metrics

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Clinical retrospective study of bone ring technique for 3-dimensional bone augmentation in implant restoration Chen Gang Chinese Journal of Oral Implantology    2024, 29 (5): 429-434.   DOI: 10.12337/zgkqzzxzz.2024.10.006 Abstract （648）      PDF （1750KB）（929）       Knowledge map    Save Objective To evaluate the efficacy and key points of the bone ring technique for three-dimensional bone augmentation with simultaneous implant placement in cases of single-tooth loss with bone defects. Methods A retrospective review of cases from August 2010 to February 2023 at the Department of Dentistry, Peking University Shenzhen Hospital, and U-dental Clinic in Shenzhen, where patients with single-tooth vertical bone defects were treated using the autogenous bone ring technique with simultaneous implant placement. Second-stage surgeries were performed 6 months postoperatively for final restorations. Complications, bone augmentation outcomes, implant failures, and postoperative bone resorption were assessed through clinical and radiographic evaluations. Results 167 teeth were treated with the bone ring technique. 2 implants failed before restoration, and 4 bone rings failed during the healing period. No further implant failures were observed after restoration. Of the 36 patients with complete CBCT data, the average vertical bone gain was (4.52±0.81) mm. Average vertical bone resorption was (0.25±0.11) mm at 6 months post-surgery and (0.52±0.23) mm at 1 year after final restoration. Conclusion The bone ring technique, when applied to cases with sufficient basal bone and vertical bone defects, is an effective method for achieving vertical bone augmentation with simultaneous implant placement. It demonstrates a high implant success rate and low complication rate. Reference | Related Articles | Metrics