Study on the preparation and antibacterial properties of polytetrafluoroethylene film modified customized titanium mesh

doi:10.12337/zgkqzzxzz.2023.12.010

Abstract

Abstract: Objective By preparing polytetrafluoroethylene film on the surface of customized titanium mesh, the biocompatibility and antibacterial ability of the surface of customized titanium mesh were improved. Methods The surface of the customized titanium mesh was sandblasted to roughen the surface by alumina and air-sprayed with PTFE dispersion. The polytetrafluoroethylene film modified customized titanium mesh (PMTM) was obtained by sintering and heat curing. The experimental groups were selective laser melting printing untreated group (CON), mechanical polishing group (MP), low-grit sandblasting group (SB), titanium-reinforced dense polytetrafluoroethylene film group (TRDP). The surface morphology, roughness, hydrophilicity, functional groups and phase composition of the samples were analyzed. The number and morphology of bacteria adhering to the surface of each group of samples after co-culture with Staphylococcus aureus and Escherichia coli were analyzed to evaluate the in vitro antibacterial ability of polytetrafluoroethylene film modified customized titanium mesh. Results The polytetrafluoroethylene film with stable bonding and a high purity is formed on the surface of the PMTM group, which reduced the micron-scale roughness and is highly hydrophobic. The number of bacteria on the surface of the CON group was the largest (P<0.001), and the numbers of bacteria on the surface of the MP and SB groups were lower. The PMTM and TRDP groups had the lowest bacterial adhesion, and their antibacterial adhesion effects were similar (P>0.05). Conclusion The preparation of polytetrafluoroethylene film on the surface of customized titanium mesh can improve its ability to inhibit bacterial adhesion, which is an ideal surface treatment method for customized titanium mesh.

Key words: Customized titanium mesh, Polytetrafluoroethylene, Guided bone regeneration, Surface treatment, Antibacterial properties

Yang Bo, Han Zekui, Dai Haoran, Zhang Liang, Zang Yixin, Wang Xinyu, Su Yucheng. Study on the preparation and antibacterial properties of polytetrafluoroethylene film modified customized titanium mesh[J]. Chinese Journal of Oral Implantology, 2023, 28(6): 451-459.

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