亲水表面改性的种植体不同时相的骨结合情况和组织学观察

doi:10.12337/zgkqzzxzz.2021.02.006

中国口腔种植学杂志 ›› 2021, Vol. 26 ›› Issue (1): 25-30.DOI: 10.12337/zgkqzzxzz.2021.02.006

亲水表面改性的种植体不同时相的骨结合情况和组织学观察

王凌霄¹, 单兆臣¹, 高振华¹, 宿玉成²

¹首都医科大学附属北京口腔医院 100050;
²中国医学科学院北京协和医院口腔种植中心北京瑞城口腔种植医学研究院 100032

收稿日期:2020-11-02 出版日期:2021-02-10 发布日期:2021-06-04
通讯作者: 单兆臣,Email：shanzhch629@163.com,电话：010-57099265, 博士、主任医师、教授、博士研究生导师,研究方向：牙槽外科和口腔种植相关研究
作者简介:王凌霄,博士生,研究方向：口腔颌面外科学和口腔种植研究
基金资助:
国家重点研发计划资助（2016YFC1102604）

Osseointegration and histological observation of chemically modified implants in different phases

Wang Lingxiao¹, Shan Zhaochen¹, Gao Zhenhua¹, Su Yucheng²

¹Beijing Stomatological Hospital, Capital Medical University,Beijing 100050, China;
²Dental Implant Center,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences, Beijing Citident Implant Training College, BITC, Beijing 100032, China

Received:2020-11-02 Online:2021-02-10 Published:2021-06-04
Contact: Zhaochen Shan, Email: shanzhch629@163.com, Tel: 0086-10-57099265
Supported by:
National Key R&D Program of China（2016YFC1102604）

摘要/Abstract

摘要： 目的观察亲水表面改性处理口腔种植体的骨结合效果。方法 4只比格犬,随机分为2周、4周、8周和12周组,于每组犬拔牙2个月后的下颌骨中植入4颗亲水表面改性处理的口腔种植体,按照相应时点取材,测量种植体稳定系数(Implant stability factor,ISQ)、临界旋出扭矩（Critical spin out torque,CST）、骨结合率,并观察不同时点骨结合的状态和组织学特点。结果种植体植入后4周与2周相比,ISQ、CST、骨结合率均显著升高;8 W与4 W相比,CST、骨结合率均显著升高;12 W与8 W相比,骨结合率显著升高。结论亲水表面改性处理能够促进种植体骨结合。

关键词: 亲水表面改性, 骨结合, 比格犬

Abstract: Objective To observe the osseointegration effect of hydrophilic surface modified dental implants. Methods four beagle dogs were randomly divided into 2week, 4week, 8week and 12 week groups. Four hydrophilic surface modified dental implants were implanted into the mandible of 2 months after tooth extraction in each group. Results the ISQ, critical rotation torque and osseointegration rate were significantly increased at 4 weeks compared with 2 weeks; the critical rotation torque and osseointegration rate were significantly increased at 8 weeks compared with 4 weeks; the osseointegration rate was significantly increased at 12 weeks compared with 8 weeks. Conclusion Hydrophilic surface modified surface treatment promotes osseointegration of implants.

Key words: hydrophilic surface modification, osseointegration, Beagle dog

王凌霄,单兆臣,高振华,等. 亲水表面改性的种植体不同时相的骨结合情况和组织学观察[J]. 中国口腔种植学杂志, 2021, 26(1): 25-30. DOI: 10.12337/zgkqzzxzz.2021.02.006

Wang Lingxiao, Shan Zhaochen, Gao Zhenhua, Su Yucheng. Osseointegration and histological observation of chemically modified implants in different phases[J].Chinese Journal of Oral Implantology, 2021, 26(1): 25-30.DOI: 10.12337/zgkqzzxzz.2021.02.006.

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亲水表面改性的种植体不同时相的骨结合情况和组织学观察

Osseointegration and histological observation of chemically modified implants in different phases

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