中国口腔种植学杂志 ›› 2022, Vol. 27 ›› Issue (2): 82-86.DOI: 10.12337/zgkqzzxzz.2022.03.006

• 论著·基础研究 • 上一篇    下一篇

初探选择性激光熔融钛表面的形态特征及机械性能

王璇1, 段彦盛1, 宋爽2, 王舒妍1, 赵国强1, 赵文爽1, 杨瑞1, 田欢1, 刘向东1, 陈旭涛1, 丁锋1, 宋应亮1, 张思佳1   

  1. 1军事口腔医学国家重点实验室 国家口腔疾病临床医学研究中心 陕西省口腔生物工程技术研究中心 第四军医大学口腔医院口腔种植科,西安 710032;
    2北京大学口腔医学院 100081
  • 收稿日期:2021-12-01 出版日期:2022-04-30 发布日期:2022-05-07
  • 通讯作者: 宋应亮,Email:songyingliang@163.com,电话:029-84776454;张思佳,Email:2380857628@qq.com,电话:029-84776454
  • 作者简介:王璇,博士在读,研究方向:临床种植与相关风险因素以及激光技术在口腔种植中的应用;张思佳,副教授、副主任医师、硕士研究生导师,研究方向:临床种植与相关风险因素以及激光技术在口腔种植中的应用;宋应亮,教授、主任医师、博士研究生导师,研究方向:临床种植与相关风险因素以及激光技术在口腔种植中的应用
  • 基金资助:
    国家博士后科学基金(2019M653968); 国家自然科学基金(81771107,82001022)

Surface characteristics and mechanical properties of titanium implant modified by selective laser melting technology

Wang Xuan1, Duan Yansheng1, Song Shuang2, Wang Shuyan1, Zhao Guoqiang1, Zhao Wenshuang1, Yang Rui1, Tian Huan1, Liu Xiangdong1, Chen Xutao1, Ding Feng1, Song Yingliang1, Zhang Sijia1   

  1. 1State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases&Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Dental Implantology, School of Stomatology, the Fourth Military Medical University, Xi'an 710032, China;
    2Peking University School and Hospital of Stomatology, Beijing 100081, China
  • Received:2021-12-01 Online:2022-04-30 Published:2022-05-07
  • Contact: Song Yingliang, Email: songyingliang@163.com, Tel: 0086-29-84776454; Zhang Sijia, Email: 2380857628@qq.com, Tel: 0086-29-84776454
  • Supported by:
    China Postdoctoral Science Foundation(2019M653968); National Natural Science Foundation of China(81771107, 82001022)

摘要: 目的 建立SLM处理钛种植体表面,通过机械性能及生物安全性实验探索其应用于种植体表面处理的可能性。方法 制作种植体及钛片样本并分为SLM组,喷砂酸蚀(SLA)组和无处理组,观察表面微形貌,测量表面粗糙度,评价其机械性能。表面使用人牙龈成纤维细胞培养,观察细胞形态和生长增殖情况。结果 SLM组微表面呈蜂窝状、孔隙不规则、层次丰富、呈峰谷形状。SLM表面粗糙度最高,平均粗糙度为(0.908±0.015)μm,峰谷粗糙度为(1.589±0.1603)μm。机械强度适宜,平均压缩强度为(110±2.5)MPa。SLM表面生物安全性评价良好,人牙龈成纤维细胞的黏附生长正常。结论 SLM处理钛种植体表面生物安全性良好,且具有较高的表面粗糙度,机械强度合适。SLM处理钛种植体表面具有临床应用的潜质。

关键词: 选择性激光熔融, 种植体, 表面处理

Abstract: Objective To establish the surface of titanium implants treated by SLM, and explore the relevant mechanisms that may improve the osseointegration level of implants through in vitro experiments. Methods Implant and titanium sheet samples were prepared and divided into SLM group, sand blasting and acid etching (SLA) group and control group. Surface microtopography was observed, roughness was measured, and mechanical properties were evaluated. HGF-C339 cells was used to observe the morphology, growth and proliferation of surface cells. Results The surface of SLM group was honeycomb, with irregular pores, rich layers and peak-valley shape. roughness of SLM surface was the highest, the mean Ra value was(0.908±0.015)μm, the mean Rz value was(1.589±0.160.3)μm. SLM surface had suitable mechanical strength, the mean yield strengths were(110±2.5)MPa. SLM surface biosafety was well evaluated, and the adhesion growth of HGF-C339 cells was normal. Conclusion The surface of titanium implants treated with SLM has good bio-safety, high surface roughness, and suitable mechanical strength. The surface of titanium implants treated with SLM could be a new approach for surface treatment.

Key words: Selective laser melting, Implant, Surface treatment