中国口腔种植学杂志 ›› 2024, Vol. 29 ›› Issue (4): 371-377.DOI: 10.12337/zgkqzzxzz.2024.08.013

• 综述 • 上一篇    下一篇

口腔种植治疗中骨再生材料的研究现状

李歆1, 刘开政2, 武诗语3, 刘远翔3, 黄宝鑫3, 乔威4, 潘浩波2, 陈卓凡3   

  1. 1深圳大学临床医学中心 深圳大学口腔研究中心 深圳大学总医院口腔科 518055;
    2中国科学院深圳先进技术研究院人体组织与器官退行性研究中心,深圳 518055;
    3中山大学附属口腔医院光华口腔医学院 广东省口腔医学重点实验室,广州 510055;
    4香港大学牙医学院应用口腔科学及社会牙医学系,香港 999077
  • 收稿日期:2023-09-11 出版日期:2024-08-30 发布日期:2024-08-16
  • 通讯作者: 陈卓凡,Email:chzhuof@mail.sysu.edu.cn,电话:020-87599860
  • 作者简介:李歆 博士、主治医师,研究方向:口腔相关抗菌及再生材料基础与转化研究; 陈卓凡 博士、主任医师、博士生导师,研究方向:口腔种植相关再生材料基础与转化研究
  • 基金资助:
    国家自然科学基金(81970975、32201097、82201124、U2001221、32161160327); 广东省自然科学基金-面上项目(2023A1515011963); 深港澳科技计划项目-C类项目(SGDX20220530111405038); 深圳市科技计划资助(JCYJ20200109114620793); 深圳市高等院校稳定支持计划面上项目(20220810163811002); 深圳市海外高层次人才科研启动经费(RC00336)

Recent progress in bone regenerative materials for implant dentistry

Li Xin1, Liu Kaizheng2, Wu Shiyu3, Liu Yuanxiang3, Huang Baoxin3, Qiao Wei4, Pan Haobo2, Chen Zhuofan3   

  1. 1Clinical Medical Academy, Institute of Stomatological Research, Shenzhen University, Department of Stomatology, Shenzhen University General Hospital, Shenzhen 518055, China;
    2Research Center for Human Tissue and Organ Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China;
    3Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China;
    4Applied Oral Sciences & Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, China
  • Received:2023-09-11 Online:2024-08-30 Published:2024-08-16
  • Contact: Chen Zhuofan, Email: chzhuof@mail.sysu.edu.cn, Tel: 0086-20-87599860
  • Supported by:
    National Natural Science Foundation of China (81970975, 32201097, 82201124, U2001221, 32161160327); Guangdong Natural Science-Fund General Programme (2023A1515011963); Shenzhen-Hong Kong-Macau Technology Research Programme-Type C (SGDX20220530111405038); Shenzhen Science and Technology Program (JCYJ20200109114620793); Stable Support Project of Shenzhen (20220810163811002); Research Fund for Overseas High-level Talents of Shenzhen (RC00336)

摘要: 当前口腔种植临床治疗中,需要涉及骨组织再生的病例逐年增加,对相关生物材料的要求日益提高。本文旨在回顾总结口腔种植骨再生材料的研究现状。结合骨再生应用的具体特点,探讨影响材料性能的生物化学及物理学性质,并对当前骨再生材料研究领域的热点重点问题进行讨论。最后进一步展望未来口腔骨种植再生材料的研究方向,以期推动下一代口腔骨再生材料的发展。

关键词: 口腔种植, 骨组织再生, 生物材料

Abstract: There has been an increasing number of cases involving bone regeneration in oral clinical treatments, and the requirements for related biomaterials are simultaneously getting higher. This review aims to summarize the research status of bone regeneration materials in the field of implant dentistry. First, specific characteristics of oral bone regeneration applications are introduced. Next, the biochemical and physical properties that affect the performance of materials are discussed, followed by some of the key issues in the field. Finally, an outlook on future research directions is provided to promote the development of next-generation oral bone regeneration materials.

Key words: Dental implant, Bone regeneration, Biomaterials