3D打印个性化钛网修复严重牙槽骨缺损的短期效果观察

doi:10.12337/zgkqzzxzz.2021.12.006

中国口腔种植学杂志 ›› 2021, Vol. 26 ›› Issue (6): 368-375.DOI: 10.12337/zgkqzzxzz.2021.12.006

3D打印个性化钛网修复严重牙槽骨缺损的短期效果观察

郭雪琪, 陈韵欣, 杨岚, 陈希立, 陈中仁, 苏汉福, 王丽萍

广州医科大学附属口腔医院种植科广东省口腔组织修复与重建工程技术研究中心广州市口腔再生医学基础与应用研究重点实验室 510182

收稿日期:2021-09-20 发布日期:2022-01-07
通讯作者: 王丽萍,Email: wanglplj@126.com,电话：020-81261560
作者简介:郭雪琪,硕士研究生、医师,研究方向：数字化精准种植与口腔颅颌面修复重建;王丽萍,主任医师、教授、博士研究生导师,研究方向：种植软硬组织再生材料与机理;口腔微生物与全身系统性疾病的临床与基础研究;数字化精准种植与口腔颅颌面修复重建
基金资助:
广东省教育厅广东省普通高校重点科研平台和科研项目（2018KTSCX186）; 广州市科技局基础研究计划项目（202002030301）

Short-term observation of 3D-printing individualized titanium mesh in restoration of severe alveolar bone defeats

Guo Xueqi, Chen Yunxin, Yang Lan, Chen Xili, Chen Zhongren, Su Hanfu, Wang Liping

Department of Dental Implantology, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou, Guangdong 510182, China

Received:2021-09-20 Published:2022-01-07
Contact: Wang Liping, Email: wamngliplj@126.com, Tel: 0086-20-81261560
Supported by:
Key Research Platforms and Projects for Regular Institutions of Higher Learning of Guangdong Provincial Department of Education (2018KTSCX186); Basic Research Plan of Guangzhou Science and Technology Bureau (202002030301)

摘要/Abstract

摘要： 目的分析探究3D打印个性化钛网（ 3D-printing individualized titanium mesh, 3D-PITM）用于修复严重牙槽骨缺损的有效性及短期临床效果。方法回顾性分析2020年12月以来于广州医科大学附属口腔医院种植科接受3D-PITM联合引导骨再生（guided bone regeneration,GBR）进行牙槽骨缺损修复的15例患者为临床研究对象,观察患者术后感染、钛网暴露及主观满意度情况,同时通过数字化技术比较术后短期骨增量效果。结果 15例患者均顺利完成手术,术后无出现感染,1例出现钛网暴露,钛网暴露率为6.0%。患者对手术过程、术后反应、术后复查等总体满意度（8.32±0.79）分。术后3个月平均水平骨增量为（3.02±1.52）mm,最高可到7.53 mm,平均垂直骨增量为（3.71±1.82）mm,最高可达7.30 mm。结论 3D打印个性化钛网用于修复严重牙槽骨缺损,术后感染率及钛网暴露率低,患者主观满意度高,具有良好的短期临床效果,其长期稳定性有待进一步随访观察。

关键词: 3D打印个性化钛网, 骨缺损, 引导骨再生, 以修复为导向, 精准修复

Abstract: Objective To investigate the short-term clinical effect of 3D-PITM in the restoration of severe alveolar bone defects. Methods Retrospective analysis of 15 objects who underwent the restoration of alveolar bone defeat by utilization of 3D-printing individualized titanium mesh (3D-PITM) combined with guided bone regeneration (GBR) in the Department of dental implantology of Affiliated Stomatology Hospital of Guangzhou Medical University since December 2020. Postoperative infection, 3D-PITM exposure, and patient satisfaction were evaluated and short-term bone augmentation was measured by digital technique. Results A total of 15 patients was included in the current study, none of them had a postoperative infection, only one of them had 3D-PITM exposure (6.0%). Patient satisfaction on the surgery process, postoperative reaction, and follow-up was evaluated to be 8.32±0.79. In 3 months, the average acquired horizontal bone augmentation was (3.02±1.52) mm (maximum at 7.53 mm), and average acquired vertical bone augmentation was (3.71±1.82) mm (maximum at 7.30 mm). Conclusion Utilization of 3D-PITM in the restoration of severe alveolar bone defeat was promising in short-term observations with low infection and exposure rate, and high patient satisfaction outcomes. However, long-term study on bone stability by 3D-PITM is also required.

Key words: 3D-printing individualized titanium mesh, Bone defect, Bone guided regeneration, Restoration guided, Precise restoration

郭雪琪,陈韵欣,杨岚,等. 3D打印个性化钛网修复严重牙槽骨缺损的短期效果观察[J]. 中国口腔种植学杂志, 2021, 26(6): 368-375. DOI: 10.12337/zgkqzzxzz.2021.12.006

Guo Xueqi, Chen Yunxin, Yang Lan, Chen Xili, Chen Zhongren, Su Hanfu, Wang Liping. Short-term observation of 3D-printing individualized titanium mesh in restoration of severe alveolar bone defeats[J].Chinese Journal of Oral Implantology, 2021, 26(6): 368-375.DOI: 10.12337/zgkqzzxzz.2021.12.006.

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3D打印个性化钛网修复严重牙槽骨缺损的短期效果观察

Short-term observation of 3D-printing individualized titanium mesh in restoration of severe alveolar bone defeats

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