Abstract: Objective： To investigate the effect of Bio-Gide membrane on guided bone regeneration in dental implants. Methods： A total of 160 patients who underwent bone regeneration in our hospital from Janu- ary to February 2018 were enrolled in the study. They were randomly divided into observation group and control group, with 80 cases in each group. The observation group was treated with Bio-Gide membrane, and the control group was treated with Haiao oral prosthetic membrane. The repair success rate, bone graft thickness, bone thickness and adverse reactions were compared between the two groups. Results： The repair success rate of the observation group was 95.00%, which was significantly higher than that of the control group (81.25%) (P<0.05). The bone graft thickness and bone thickness of the observation group were significantly higher than those of the control group(P<0.05). The incidence rate was 8.75%, which was significantly lower than that of the control group(23.75%(P<0.05). Conclusion： Bio-Gide membrane has a definite clinical effect on patients with dental implant-guided bone regeneration, which can improve the success rate of repair and reduce the occurrence of adverse reactions. It is worthy of clini- cal application.

Key words: Bio-Gide membrane, dental implant, bone regeneration