SLA-processed 3D printing and forging of TC4 surface implants in an animal model of hyperglycemia

doi:10.12337/zgkqzzxzz.2023.10.007

Abstract

Abstract: Objective To perform a comparative study of the surface properties and osseointegration ability of SLA-treated 3D printed and forged TC4 implants. Method The optimal SLA conditions were mapped and applied to the implants. Implants were implanted into rabbits, and comparative studies of the osseointegration ability of each group of implants were performed at 4, 8, and 12 weeks after surgery. Result The results of repeated measures ANOVA showed that the effect of time on the osseointegration capacity was statistically significant (P<0.001). The difference in the osseointegration rate of similar implants in Group A (hyperglycemic group) and Group B (normoglycemic group) was not statistically significant at different time periods (P=0.075, P=0.129, P=0.56, and P=0.662). The difference in the osseointegration rates of the 2 implants in groups A and B was not statistically significant (P=0.664, P=0.886, P=0.828) during the same time period. Conclusion After the novel optimized SLA treatment, both 3D printed and forged TC4 implants formed a micro- and nanoscale pitted rough surface with good hydrophilicity and suitable roughness. Both had good osseointegration ability in hyperglycemic rabbits and normoglycemic rabbits. The SLA-treated 3D-printed TC4 implants had similar osseointegration ability as the forged TC4 implants in both hyperglycemic rabbits and normoglycemic rabbits.

Key words: Ti-6Al-4V, Titanium alloy, Sandblasting acid etching, Diabetes mellitus, 3D printing

Lin Qian, Han Zekui, Song Zhenyu, Che Di, Duan Feng, Wang Xinyu. SLA-processed 3D printing and forging of TC4 surface implants in an animal model of hyperglycemia[J]. Chinese Journal of Oral Implantology, 2023, 28(5): 332-339.

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