先天性缺牙治疗的研究进展

doi:10.12337/zgkqzzxzz.2024.06.006

中国口腔种植学杂志 ›› 2024, Vol. 29 ›› Issue (3): 224-230.DOI: 10.12337/zgkqzzxzz.2024.06.006

• “先天缺牙的相关治疗及进展”重点栏目 • 上一篇下一篇

先天性缺牙治疗的研究进展

耿晨昕, 刘洋, 韩冬

北京大学口腔医学院口腔医院修复科国家口腔医学中心国家口腔疾病临床医学研究中心口腔生物材料和数字诊疗装备国家工程研究中心口腔数字医学北京市重点实验室 100081

收稿日期:2024-03-07 出版日期:2024-06-30 发布日期:2024-06-28
通讯作者: 韩冬,Email：donghan@bjmu.edu.cn, 电话：010-82195384
作者简介:耿晨昕硕士研究生在读,研究方向：先天缺牙的致病机制、遗传学诊断及多学科联合序列治疗研究;韩冬教授、主任医师、口腔医学博士、博士研究生导师,研究方向：牙发育异常的多学科序列治疗、牙发育异常的遗传学诊断和致病机制、牙发育的分子调控机制
基金资助:
国家自然科学基金（82270944）

Research advances in treatment of tooth agenesis

Geng Chenxin, Liu Yang, Han Dong

Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China

Received:2024-03-07 Online:2024-06-30 Published:2024-06-28
Contact: Han Dong , Email: donghan@bjmu.edu.cn, Tel: 0086-10-82195384
Supported by:
National Natural Science Foundation of China (82270944)

摘要/Abstract

摘要： 先天性缺牙是人类最常见的牙发育异常,影响患者的咀嚼、发音、美观及颌面部发育。由于该疾病的特殊特点,其治疗历时久、花费高,给患者带来心理和经济的双重负担。治疗方法包括儿科、正畸、颌面外科、修复、种植等多学科协作的序列治疗,以及靶向分子治疗和组织工程技术等新兴手段。本文综述了先天性缺牙的疾病特点、传统治疗方式的新进展以及新兴的治疗方法,简述了不同治疗方法的治疗效果,旨在为先天性缺牙患者的临床治疗提供有意义的信息。

关键词: 先天性缺牙, 多学科序列治疗, 牙种植, 分子靶向治疗, 牙再生

Abstract: Tooth agenesis is the most common dental developmental anomaly in humans, which can cause significant chewing, pronunciation, aesthetic and craniofacial development problems. Due to the unique characteristics of tooth agenesis, its treatment is very time-consuming and costly, imposing huge economic burdens and mental stress on patients. The treatments include a sequential therapeutic strategy with a multidisciplinary team of pediatric dentistry, prosthodontics, oral and maxillofacial surgery, orthodontics, oral implantology, and other backgrounds, as well as emerging methods such as targeted molecular therapy and tissue engineering. This review provides an update on the knowledge on the characteristics of tooth agenesis, traditional treatments, and the rising fields of molecular therapy and tissue engineering. We also discuss the treatment effects of each method, aiming to provide a reference for the treatment of tooth agenesis.

Key words: Tooth agenesis, Multidisciplinary and sequential treatment, Dental implants, Molecular targeted therapy, Tooth regeneration

耿晨昕,等刘洋,等韩冬. 先天性缺牙治疗的研究进展[J]. 中国口腔种植学杂志, 2024, 29(3): 224-230. DOI: 10.12337/zgkqzzxzz.2024.06.006

Geng Chenxin, Liu Yang, Han Dong. Research advances in treatment of tooth agenesis[J].Chinese Journal of Oral Implantology, 2024, 29(3): 224-230.DOI: 10.12337/zgkqzzxzz.2024.06.006.

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先天性缺牙治疗的研究进展

Research advances in treatment of tooth agenesis

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