Research progress in the construction of murine experimental model of peri-implantitis

doi:10.12337/zgkqzzxzz.2025.06.013

Abstract

Abstract: Peri-implantitis is one of the most intractable complications in dental implant treatment, which is also the key factor for implant failure. The construction of relevant animal experimental models that can accurately simulate the pathological features of peri-implantitis is crucial for in-depth exploration of its pathogenesis. This review systematically collates the research progress in recent years on the establishment of murine experimental models of peri-implantitis. The content encompasses the scientific selection of experimental animals, the application of innovative modeling methods, modeling time, the accurate evaluation of modeling outcome indicators, and an in-depth analysis of key factors such as success rate. The aim is to provide more comprehensive and accurate references for researchers in this field.

Key words: Peri-implantitis, Murine, Animal model

Sun Yuxin, Shi Bin, Wu Tao. Research progress in the construction of murine experimental model of peri-implantitis[J]. Chinese Journal of Oral Implantology, 2025, 30(3): 281-287.

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