Effects of selective serotonin reuptake inhibitor on skeletal system and osseointegration of oral implants

doi:10.12337/zgkqzzxzz.2022.04.013

Abstract

Abstract: Selective serotonin reuptake inhibitor (SSRI) is the most widely used antidepressant. Existing studies have shown that SSRI impairs osteogenic function, reduces bone mineral density, inhibits bone healing, and may inhibit osseointegration of implants. This article introduces the pharmacological action of SSRI, its effect on skeletal system and its mechanism, and discusses the research status of oral implant failure related to SSRI use.

Key words: Antidepressant, Implant failure, SSRI, Osseointegration

Li Shunshun, Wang Feng. Effects of selective serotonin reuptake inhibitor on skeletal system and osseointegration of oral implants[J]. Chinese Journal of Oral Implantology, 2022, 27(2): 124-129.

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