Chinese Journal of Oral Implantology ›› 2021, Vol. 26 ›› Issue (3): 196-201.DOI: 10.12337/zgkqzzxzz.2021.06.010

• Case Reports • Previous Articles     Next Articles

Research progress of immune cells in the process osseointegration

Li Xiaoyu, Cai Qing, Yin Zhaoyi, Jin Zhuohua, Wang Zixuan, Meng Weiyan   

  1. Department of dental Implantology, Hospital of Stomatology, Jilin University&Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun 130021, China
  • Received:2021-01-07 Online:2021-06-10 Published:2021-07-14
  • Contact: Meng Weiyan, Email: mengwy@jlu.edu.cn,Tel: 0086-433-88796025
  • Supported by:
    Science and Technology Development Plan of Science and Technology Department of Jilin Province(20200404108YY);Science and Technology Projects of Finance Department of Jilin Province(JCSZ2019378-3); Jilin Provincial Development and Reform Commission(JCSZ2020304-1)

Abstract: High-quality osseointegration is the key to the success rate and long-term survival rate of implants. Immune cells could remove the tissue fragment and pathogen, regulate the inflammatory reaction, induce the recruitment of mesenchymal stem cells and osteogenic differentiation, etc., which could improve the osteogenic microenvironment and play an essential role in the process of implant osseointegration. In order to optimize the strategy of immune regulation for forming better implant osseointegration, this article will review the specific functions of different immune cells in the process of implant osseointegration.

Key words: Dental implants, Osseointegration, Neutrophils, Macrophage, Mesenchymal stem cells, Bone biomaterial