Chinese Journal of Oral Implantology ›› 2024, Vol. 29 ›› Issue (3): 277-283.DOI: 10.12337/zgkqzzxzz.2024.06.014

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Effects of proton pump inhibitors on osseointegration of oral implants

Wang Mingyang, Huang Haitao   

  1. Department of Stomatology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China
  • Received:2023-11-22 Online:2024-06-30 Published:2024-06-28
  • Contact: Huang Haitao, Email: dlykfykq1999@163.com, Tel: 0086-411- 83635963-3287

Abstract: Proton pump inhibitors (PPIs) are commonly used drugs to treat conditions related to abnormal gastric acid secretion. They have been found to affect bone metabolism, which can impact bone healing. There is ongoing research on the potential impact of PPIs on the success of implant surgery. Current studies suggest that PPIs may have a limited effect on implant failure rates. Therefore, caution should be exercised when considering treatment plans for patients taking PPIs, and discontinuing PPIs solely to improve implant success rates is not recommended.

Key words: Proton pump inhibitors, Osseointegration, Dental implants