中国口腔种植学杂志 ›› 2023, Vol. 28 ›› Issue (2): 109-113.DOI: 10.12337/zgkqzzxzz.2023.04.007

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微量元素改性PEEK种植体的研究进展

罗桂生1, 刘雨蒙1, 王鹏来1,2, 袁长永1,2   

  1. 1徐州医科大学口腔医学院 221004;
    2徐州医科大学附属口腔医院种植科 221000
  • 收稿日期:2022-11-02 出版日期:2023-04-30 发布日期:2023-05-04
  • 通讯作者: 袁长永,Email: 24503692@qq.com,电话:0516-85866012
  • 作者简介:罗桂生,硕士研究生在读,研究方向:口腔种植学相关研究; 袁长永,博士、副教授、副主任医师、硕士研究生导师,研究方向:前牙美学区种植、即刻种植及数字化种植技术
  • 基金资助:
    江苏省研究生科研与实践创新计划项目(KYCX22_2973)

Research progress on trace elements modification of PEEK implant

Luo Guisheng1, Liu Yumeng1, Wang Penglai1,2, Yuan Changyong1,2   

  1. 1School of Stomatology, Xuzhou Medical University, Xuzhou 221004, China;
    2Department of Oral Implantology, Affiliated Stomatological Hospital of Xuzhou Medical University, Xuzhou 221000, China
  • Received:2022-11-02 Online:2023-04-30 Published:2023-05-04
  • Contact: Yuan Changyong, Email: 24503692@qq.com, Tel: 0086-516-85866012
  • Supported by:
    Jiangsu Province Postgraduate Research and Practice Innovation Project(KYCX22_2973)

摘要: 聚醚醚酮(polyetheretherketone ,PEEK)是一种高性能特种塑料,它的力学性能和生物相容性较好,且易于加工成型,已成为牙科种植体的备选材料。PEEK由于缺乏生物活性以及易导致菌斑聚集,限制了其在口腔种植领域的临床应用。目前很多学者通过微量元素改性的方法解决了PEEK的生物惰性和菌斑附着问题。不同微量元素各具优势,锶、钽、锰等元素可以促进成骨细胞分化,氟、银、锌等元素则可以抑制致炎细菌生长,多种微量元素共修饰赋予PEEK种植体更为多元化的性能。

关键词: 聚醚醚酮, 牙种植体, 微量元素改性, 成骨性能, 抗菌能力

Abstract: Polyetheretherketone (PEEK) is a high-performance specialty plastic with good mechanical properties and biocompatibility and is easy to process and form, making it an alternative material for dental implants. However, the lack of biological activity and the easy accumulation of plaque limit the clinical application of PEEK in the field of oral implantology. At present, many scholars solve the problem of biological inertia and plaque attachment of PEEK through trace elements modification. Different trace elements have their own advantages. Strontium, tantalum, manganese, and other elements can promote osteoblast differentiation. Fluorine, silver, zinc, and other elements can inhibit the growth of inflammatory bacteria, and the co-modification of various trace elements gives PEEK implant more diversified properties.

Key words: PEEK, Dental implant, Trace elements modification, Osseointegration, Antibacterial ability