中国口腔种植学杂志 ›› 2022, Vol. 27 ›› Issue (1): 58-63.DOI: 10.12337/zgkqzzxzz.2022.02.012

• 综述 • 上一篇    

取骨方式对自体骨活性及在引导骨再生术中成骨效应的影响

干嘉雯1, 窦嘉琪1, 徐陈词1, 吴轶群1,2, 王凤1,3   

  1. 1上海交通大学口腔医学院 200001;
    2上海交通大学医学院附属第九人民医院·口腔医学院口腔第二门诊部 上海交通大学口腔医学院 国家口腔医学中心 国家口腔疾病临床医学研究中心 上海市口腔医学重点实验室 200001;
    3上海交通大学医学院附属第九人民医院·口腔医学院口腔种植科 上海交通大学口腔医学院 国家口腔医学中心 国家口腔疾病临床医学研究中心 上海市口腔医学重点实验室 200001;
  • 收稿日期:2021-12-14 发布日期:2022-03-09
  • 通讯作者: 吴轶群,Email: yiqunwu@hotmail.com,电话:021-56152705;王凤,Email: diana_wangfeng@aliyun.com ,电话:021-53315299

Impact of bone harvesting methods on cell viability of autogenous bone particles in guided bone regeneration

Gan Jiawen1, Dou Jiaqi1, Xu Chenci1, Wu Yiqun1,2, Wang Feng1,3   

  1. 1College of Stomatology, Shanghai Jiao Tong University, Shanghai 200001, China;
    2Department of Second Dental Center, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai 200001, China;
    3Department of Oral Implantology, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China
  • Received:2021-12-14 Published:2022-03-09
  • Contact: Wu Yiqun, Email: yiqunwu@hotmail.com, Tel: 0086-21-56152705; Wang Feng, Email: diana_wangfeng@aliyun.com, Tel: 0086-21-53315299

摘要: 临床牙槽骨缺损可以采用各类骨增量材料进行修复重建,但对于骨缺损大的区域,获取和加入一定比例的自体骨是获得良好成骨预后的一个重要环节。临床制取自体骨屑的方法有很多种,包括通过手持器械如骨凿、刮骨器取骨,采用机用旋转器械如取骨环钻、超声骨刀、骨吸引收集器等。文章总结了不同取骨方法所获得自体骨的活性及成骨效能,希望为临床引导骨再生取骨时使用工具的选择提供参考,以获得最佳骨诱导效果,提高骨重建的质量。

关键词: 引导骨再生, 自体骨, 细胞活性, 取骨技术

Abstract: A variety of bone substitute materials can be used to repair and reconstruct clinical alveolar bone defects, but in the site with great bony volume insufficiency, it is very important to harvest and add a certain proportion of autogenous bone particles to achieve better clinical outcomes. The approaches to gain autografts include handheld instruments such as chisels and scrapers, rotating instruments such as trephines, piezoelectric instruments, and bone filters. It remains unclear which harvesting methods can provide autografts with the greatest osteoinductive and osteogenic potential in clinical bone augmentation. This review mainly summarized surgical results of different scholars using different methods of bone extraction from different sources of autologous bone, hoping to provide a reference for the selection of tools for bone extraction during clinical guidance of bone regeneration, to obtain the best bone induction effect and improve the quality of bone reconstruction.

Key words: Guided bone regeneration, Autogenous bone grafts, Cell viability, Bone harvesting techniques