Chinese Journal of Oral Implantology ›› 2025, Vol. 29 ›› Issue (6): 596-601.DOI: 10.12337/zgkqzzxzz.2024.12.024

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Effectiveness of concentrated growth factors in sinus floor elevation: a review

Ou Yanjing1,2,3, Chen Jiang2,3   

  1. 1Fujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatology Key Lab of Fujian College and University, Fuzhou 350004, Fujian, China;
    2School of Stomatology, Fujian Medical University, Craniomaxillofacial Implant Research Center, Fujian Medical University, Fuzhou 350004, Fujian, China;
    3School and Hospital of Stomatology, Fujian Medical University, Fuzhou 350004, Fujian, China
  • Received:2024-07-19 Online:2025-01-02 Published:2025-01-02
  • Contact: Chen Jiang, Email: jiangchen@fjmu.edu.cn, Tel: 0086-591-83700838

Abstract: Maxillary sinus floor elevation has become a routine procedure for addressing insufficient bone volume in the atrophic posterior maxilla. Various bone grafting materials, including autologous bone, allografts, xenografts, and synthetic bone substitutes, have been used to achieve adequate bone augmentation for dental implant placement. Concentrated growth factor (CGF), a new generation of platelet concentrate, features a dense fibrin structure enriched with multiple growth factors that regulate cell adhesion, proliferation, differentiation, and angiogenesis. This review focuses on the effects of CGF on implant success rates, the quality of newly formed bone, and the incidence of postoperative complications in maxillary sinus floor elevation procedures.

Key words: Maxillary sinus floor elevation, Bone graft materials, Concentrated growth factor (CGF)