Chinese Journal of Oral Implantology ›› 2023, Vol. 28 ›› Issue (2): 102-108.DOI: 10.12337/zgkqzzxzz.2023.04.006

• Meta Analysis • Previous Articles     Next Articles

The autologous platelet concentrates for maxillary sinus floor elevation: an overview of systematic reviews

Gong Jiaming1,3, Zhao Ruimin1, Zhang Qihang2, Yu Zhanhai2, Su Linhan1   

  1. 1Department of Stomatology, The 940th Hospital of Joint Logistics Support Force of People's Liberation Army, Lanzhou 730050, China;
    2Department of Oral Implant, School/Hospital of Stomatology, Lanzhou University, Lanzhou 730000, China;
    3Department of Stomatology, Quzhou Hospital Affiliated to Wenzhou Medical University (Quzhou People's Hospital), Quzhou 324002, Zhejiang, China
  • Received:2022-11-24 Online:2023-04-30 Published:2023-05-04
  • Contact: Su Linhan, Email: 14917731@qq.com, Tel: 0086-931-8994810
  • Supported by:
    Natural Science Foundation of Gansu Province (21JR11RA006)

Abstract: Objective To evaluate the quality of methodology and evidence of the systematic reviews and meta-analyses (SR/MA) of autologous platelet concentrates (APC) for maxillary sinus floor elevation (MSFE). Methods PubMed, Embase, Cochrane Library, Scopus, CNKI, SinoMed, and WanFang databases were electronically searched to enroll SR/MA of APC for MSFE from inception to August 31, 2022. Two reviewers independently screened literature, extracted data, and employed the AMSTAR 2 and the GRADE for evaluating the quality of methodology of the included studies and the certainty of the evidence for outcomes respectively. Results A total of 13 SR/MA were included and the major conclusions were that APC presents limited influence on MSFE and might promote the healing of sinus tissue. The 9 items of AMSTAR 2 were reported well, and two items were not reported in any of the included SRs, and the quality was relatively convinced. The evidence grading of GRADE revealed that, in the total of 46 outcomes, 9 were graded as high-level, 25 as medium-level, 11 as low-level, and 1 as extremely low-level. Conclusion Most of the current evidence shows the advantages of APC in MSFE are not obvious, but the reliability of SR/Ma is inconsistent. High-quality clinical trials are still needed to verify the efficacy of APC for MSFE

Key words: Autologous platelet, Maxillary sinus floor elevation, Clinical trials, Overview of systematic reviews, AMSTAR 2, GRADE