Progress of demineralized dentin matrix as scaffold material for dental stem cells

doi:10.12337/zgkqzzxzz.2023.10.011

Abstract

Abstract: Tissue engineering uses the cooperation of cells, bioactive materials and extracellular matrix to achieve tissue regeneration. As a scaffold material in tissue engineering, demineralized dentin matrix can simulate extracellular matrix microenvironment, promote odontogenic differentiation of stem cells, and be used for regeneration of dental pulp, dentin and periodontal tissues. In dental tissue engineering, demineralized dentin matrix and dental stem cells are used to repair dental pulp exposure and root regeneration, which can reproduce the anatomical structure and function of dental tissues in the body. It is expected to replace the traditional pulp capping agent to repair damaged teeth in the future, replace the traditional implant for restoration, and realize tooth regeneration.

Key words: Tissue engineering, Demineralized dentin matrix, Dental stem cells

Wu Daomin, Bao Jibo, Zhu Qiuyan, Xie Zhigang. Progress of demineralized dentin matrix as scaffold material for dental stem cells[J]. Chinese Journal of Oral Implantology, 2023, 28(5): 358-363.

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