Abstract: Guided bone regeneration (GBR) is a popular method for bone augmentation in oral implant restoration. Titanium mesh has become increasingly prevalent due to its excellent mechanical properties and support fixation. However, traditional prefabricated titanium mesh has limitations, such as poor fitting with the alveolar bone shape, which can result in complications such as wound tearing, mucosal damage, and titanium mesh exposure. Additive manufacturing technology, such as 3D printing, allows for the customization of customized titanium mesh with varying shapes, thicknesses, and porosity. This customized approach not only upholds the excellent mechanical properties and biocompatibility of traditional titanium meshes but also achieves high-precision bone grafting through meticulous preoperative design and digital virtual reconstruction. Such an approach not only streamlines the surgical procedure and shortens surgery time, but also simplifies the surgeon’s operations and reduces trauma to patients. However, in clinical application, even though postoperative complications have decreased, issues such as the exposure of the titanium mesh persist and require careful attention. Despite the considerable clinical potential of titanium mesh from customized manufacturing, in-depth subsequent research is crucial to enhance its effectiveness. This article provides an overview of the current clinical application and research status of customized additive manufactured titanium mesh.

Key words: Customized manufacturing of titanium mesh, Bone augmentation, Guided bone regeneration, Additive manufacturing technology, Titanium metal materials