Abstract: Objective: To investigate the clinical application of advanced platelet-rich fibrin(A-PRF) in intramaxillary sinus lifting. Methods: 26 patients(42teeth) with insufficient residual alveolar ridge height of maxillary posterior teeth of implant patients in our hospital were selected. Osstem TS Ⅲ implant system was adopted. Bone condensing and hydraulic lifting method were combined with internal lifting via alveolarridge approach. A-PRF was used as implant and implant was implanted at the same time.Denture repair was performed from 6 to 8 months after operation. Results: Curved surface tomography showed that the elevation of maxillary sinus was 3.3mm-7.8mm(average 6.1mm), and 42 teeth of 26 patients achieved good bone union. Conlusion: Advanced platelet rich fibrin(A-PRF) is a completely autogenous blood derived tissue, which has no foreign body reaction and can induce soft and hard tissue formation. It can be used as an effective and low-cost biomaterial for maxillary sinus lifting.

Key words: advanced platelet rich fibrin(A-PRF), intra-maxillary sinus floor lifting, bone augmentation