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Table of Content

    10 December 2019, Volume 24 Issue 4
    Effect of hydrophilicity of titanium with micro/nanotopographical surface on osteogenic differentiation of human periodontal ligament cells via p53/CXCL12
    LIN Yujiao, ZHUANG Xiumei, XIE Yiwen
    2019, 24(4):  154-157.  DOI: 10.12337/zgkqzzxzz.2019.12.002
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    Objective: To investigate the effect of p53/CXCL12 on the osteogenic differentiation of periodontal ligament cells(PDLCs) induced by hydrophilicity of titanium with micro/nanotopographical surface. Methods: Anodic oxidation and sandblast-alkali heat methods were used to establish scale structures, which were cultured with PDLCs. Expressions of p53 and CXCL12 were examined by western blot at 7 day. After transfection of p53 or CXCL12 with siRNA, p53 and CXCL12 level were furthered detected, changes of alkaline phosphatase(ALP) activity and mRNA expressions of such osteogenic markers as ALP, collagen- I(COL1) and runt related transcription factor 2(RUNX2) were examined to detect osteogenic differentiation of PDLCs. Date was statistically analyzed with SPSS13.0 software package. Results: Compared with anodic oxidation surfaces, p53 expression of PDLCs on sandblast-alkali heat surface discs with well hydrophilicity was significantly decreased, while CXCL12 level increased. Transfected with Si-p53, p53 level was decreased and CXCL12 level increased. After transfection of Si-CXCL12, CXCL12 level was decreased, but no significant change of p53 level. However, ALP activity and ALP, COL1 and RUNX2 mRNA levels were significantly decreased. Conclusion: Hydrophilicity of titanium with micro/nanotopographical surface promotes osteogenic differentiation of PDLCs via p53/CXCL12.
    Application of fixed temporary denture with dental support in primary closing immediate implant wound of upper anterior teeth
    YANG Rui, XU Zhijie
    2019, 24(4):  158-161.  DOI: 10.12337/zgkqzzxzz.2019.12.003
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    Objective: To investigate the clinical effect of primary closure of upper anterior teeth implantation with fixed temporary denture supported by teeth. Methods: 29 immediate implant sites of upper anterior teeth were included in the study. Absorbable biofilm or gelatin sponge were used to preliminarily cover the surgical wounds, and fixed temporary denturewith dental support was made to completely close the wounds. The success rate of implantation and the changes of red aesthetics before and after treatment were evaluated. Results: Osseointegration occurred in all implants. The success rate is 100%. There was no significant change in red aesthetic index after implanting compared with that before implanting(P> 0.05). Conclusion: Closing immediate implant wounds with fixd temporary denture supported by teeth Can achieve good clinical results.
    CBCT study of alveolar bone changes in the posterior teeth
    HU Changqi, WEI Hongwu
    2019, 24(4):  162-165.  DOI: 10.12337/zgkqzzxzz.2019.12.004
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    Objective: To investigate the bone changes in the posterior region immediately after the use of platelet-rich fibrin(PRF) to fill the interstitial space. Methods: From December 2017 to December 2018, 15 patients were implanted immediately in the posterior region, and 18 implants were implanted. All patients were covered with PRF to cover the gap between the implant and the alveolar bone wall. CT was taken on the day after and 6 months after surgery, and the bone height around the implant and the thickness of the buccal and lingual bone plate were observed on the day after surgery and 6 months after surgery. Results: The heights of the proximal, distal, buccal and lingual bones of the postoperative implants were(2.922±1.305)mm, (1.972±1.853)mm, (2.033±1.838)mm, (1.389±1.590)mm, and cheeks. The thickness of the lingual bone plate was (3.328±1.359) mm and (3.806±1.962) mm respectively. The height of the proximal, middle, buccal and lingual bone of the implant was(2.572±1.619)mm, respectively. (1.617±1.345)mm, (0.972±2.423)mm, (0.722±1.412)mm, and the thickness of the buccal and lingual bone plates were (2.417±1.605)mm and (2.772±1.638)mm, respectively, The height of bone in the near and far was not statistically significant(P>0.05), and the thickness of the buccal and lingual bone plate was statistically significant(P<0.05). Conclusion: The immediate use of PRF in the posterior region is simple, the soft and hard tissue is well healed, and it has good short-term effects.
    Clinical application of CBCT in the evaluation of Bio-Gide collagen membrane in the simultaneous maxillary sinus lifting
    LUO Juan, LIAO Juan, FEI Wei
    2019, 24(4):  166-170.  DOI: 10.12337/zgkqzzxzz.2019.12.005
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    Objective: To study the clinical application of CBCT in the evaluation of Bio-Gide collagen membrane in the simultaneous maxillary sinus lifting. Methods: From December 2015 to December 2018, CBCT showed 20 patients with maxillary first molar implants with insufficient bone grafting capacity (4, 000mm from alveolar crest to maxillary sinus), they were randomly divided into two groups, Group: Bio- Gide absorbable collagen membrane+bio-oss bone powder(n=10), control group: implanted bio-oss bone powder(n=10), surgical methods were performed with maxillary sinus lift surgery plus simultaneous implant implantation the implants are 10mm in length and different diameters of the Dengteng implants. Postoperative complications were evaluated 10 days after surgery and 1 month after surgery: facial swelling, red tissue swelling in the operation area, and number of infections in the operation area. CBCT was used to measure the vertical height of the maxillary first molar area before surgery, immediately after surgery and 6 months after operation. The newly formed bone mineral density(HU value) at 1 mm from the end of the maxillary sinus was measured by CBCT before and after 6 months), paired t-test was performed on the above data using SPSS 17.0 software. Results: 10 days after operation, the experimental group and the control group had swelling of the face, soft tissue swelling, and the number of infections in the operation area were (1, 2) and (0, 1) and (0, 0) respectively. The experimental group and the control group were treated 1 month after operation. There were no complications in the area, there were differences between the experimental group and the control group. Sinus distance before surgery, postoperatively and postoperatively: experimental group(5.02±0.51), (10.32±1.32) and (12.6±0.13), control group: (4.91±0.69), (10.12± 1.08) and 11.4±0.83), there was no difference between preoperative and postoperative, the difference was not statistically significant (P>0.05), there was a difference in 6 months after operation, the difference was statistically significant(P<0.001). The HU values of the experimental group and the control group before and after 6 months were (442.77±21.80) and (459.81±20.72), (442.10±23.16) and (529.50±40.67), respectively. There was no difference before operation, and the difference was not statistically significant(P> 0.05), there was a difference in 6 months after operation, and the difference was statistically significant(P< 0.001). Conclusions: Bio-oss bone powder alone can increase the vertical bone mass of the maxillary posterior teeth, but the combination with Bio-Gide absorbable collagen membrane can make the bio-oss bone powder osteogenesis better. In the short-term, the experimental group has fewer complications than the control group. In the first month of the month, both groups of patients healed well
    Clinical application of A-PRFin intra-maxillary sinus lifting
    LEI Shuangxi, GAO Ping, YANG Cheng, et al
    2019, 24(4):  171-173.  DOI: 10.12337/zgkqzzxzz.2019.12.006
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    Objective: To investigate the clinical application of advanced platelet-rich fibrin(A-PRF) in intramaxillary sinus lifting. Methods: 26 patients(42teeth) with insufficient residual alveolar ridge height of maxillary posterior teeth of implant patients in our hospital were selected. Osstem TS Ⅲ implant system was adopted. Bone condensing and hydraulic lifting method were combined with internal lifting via alveolarridge approach. A-PRF was used as implant and implant was implanted at the same time.Denture repair was performed from 6 to 8 months after operation. Results: Curved surface tomography showed that the elevation of maxillary sinus was 3.3mm-7.8mm(average 6.1mm), and 42 teeth of 26 patients achieved good bone union. Conlusion: Advanced platelet rich fibrin(A-PRF) is a completely autogenous blood derived tissue, which has no foreign body reaction and can induce soft and hard tissue formation. It can be used as an effective and low-cost biomaterial for maxillary sinus lifting.
    Clinical effect of planting restoration in patients with chronic periodontitis
    WANG Zhiqiang, ZHUANG Wenjie
    2019, 24(4):  174-177.  DOI: 10.12337/zgkqzzxzz.2019.12.007
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    Objective: To investigate the clinical effect of Planting restorationin chronic periodontitis patients. Methods: 96 cases of Planting restorationpatients who were treated in our hospital were selected as the research object, including 48 healthy periodontal patients as the control group and 48 patients with chronic periodontitis as the study group. Both groups were treated with dental implantation. PD(probing depth), mPLI(modified plaque index), mSBI(modified gum crevicular bleeding index) was compared of the two groups after treatment for 3 months, 6 months and 12 months, and Implantation restoration and alveolar bone resorption in 3 years and 5 years in the two groups. Results: Increase with time after planting and restoration, the level of PD, mPLI, mSB were increased, the PD in the study group was significantly higher than the control group (P<0.05), there was no significantly different of mPLI in the two groups(P>0.05), the mSBI in 3 months of the two groups was not significantly different(P>0.05), and the mSBI in the study group was significantly higher than the control group at 6 and 12 months (P<0.05). The implantation restoration in the control group was higher than the study group, but there was no significant difference between the two groups in half a year and one year(P>0.05). The implantation restoration in the control group was significantly higher than the study group at 3 and 5 years (P<0.05). The alveolar bone resorption in the study group for 3 years and 5 years was significantly higher than the control group(P<0.05). Conclusion: The short-term effect of implantation repair on chronic periodontitis patients is better, the long-term effect is significantly lower than the healthy periodontal patients due to inflammatory reaction.
    A retrospective study of flapless immediate implant and immediate restoration of single tooth in maxillary aesthetic area in 3 years
    ZHANG Bin, SUN Lihua, ZHANG Junhua, et al
    2019, 24(4):  178-183.  DOI: 10.12337/zgkqzzxzz.2019.12.008
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    Objective: To study the soft and hard tissue stability of flapless immediate implant and immediate restoration of single tooth in maxillary aesthetic area. Methods: 26 single implants in maxillary aesthetic area were included. All of the implants were placed immediately into fresh extractions and and immediately restoration, digital scanning to make temporary restorationsimmediately,The final restorations were performed after 6 months with all-ceramic crown, Control group selected intraoral dental health with the same name. On different time of follow-up, observation of probing depth(PD), modified plaque index (mPLI), modified sulcus bleeding index(mBI), gingival position, marginal bone loss. Results: The 26 implants were obtained the good stability of the soft and hard tissue and the aesthetic effect. The survival rate of both groups were 100%. The PD、mPLI、mBI value of 1, 3, 6, months was significantly higher than that of natural teeth, there was a significant difference(P<0.05), The mBI value of 36 months as significantly higher than that of natural teeth, there was a significant difference(P<0.05). The peri implant gingival degenerate 0.31mm the first 3 months than preoperative, gingival growth 0.05mm in 3-6 months, three years of gingival recession 0.36mm,midfacial papillaloss more than the distal or mesial papilla. Peri implant marginal bone loss 0.81mm with in three months after operation, Absorbed 0.97mm at 1 year. Conclusion: Flapless immediate implant and immediate prosthesis can maintain good soft and hard tissue stability, it was worth clinical promotion.
    Evaluate of the implementation value of standard operating procedures in planting care coordination
    PENG Guixue
    2019, 24(4):  184-186.  DOI: 10.12337/zgkqzzxzz.2019.12.009
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    Objective: To explore the implementation value of standard operation process in planting nursing cooperation. Methods: 240 patients admitted to our hospital from February 2018 to April 2019 were selected. They were randomly divided into two groups by computer lottery, including 120 cases in the control group, who received standard operation procedures and routine care. 120 patients in the observation group were treated with standard operation procedures in planting nursing cooperation. The treatment efficacy rate and Hamilton Anxiety Scale score were compared between the two groups. Results: the effective rate of treatment in the observation group was better than that in the control group, and the difference was statistically significant(p<0.05). The negative emotion score of patients in the observation group was significantly better than that in the control group(p<0.05). Conclusion: The implementation of standard operation flow Cheng Kewei oral planting in planting nursing cooperation lays a good foundation, and can also effectively strengthen the quality of nursing. It is worthy of clinical promotion and wide application.
    A case report about bone splitting technique combined with apically positioned flap in a narrow mandibular alveolar bone
    XIONG Hang, NIU Tao, XIE Liangkun
    2019, 24(4):  187-190.  DOI: 10.12337/zgkqzzxzz.2019.12.010
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    Objective: To investigate the clinical significance of bone splitting technique of implants. Methods: In order to decrease the volume of bone transplantation, bone splitting technique in the patient with serious bone width decrease was taken to solve the requirements of patients with less bone graft and shorten the treatment time. Results: The average bone width increase was 4.0-7.0mm, ideal aesthetic effect was harvested. Which meets the requirements of patients to decrease surgical incisions and times as much as possible, and at the same time reduces the operation ares and operation time, and shortens the operation cycle. Conclusion: Bone splitting technique is a effective and reliable bone transplantation method to these narrow alveolar.