比较个性化钛网与传统钛网在引导骨再生后暴露的系统综述

doi:10.12337/zgkqzzxzz.2022.04.011

中国口腔种植学杂志 ›› 2022, Vol. 27 ›› Issue (2): 112-118.DOI: 10.12337/zgkqzzxzz.2022.04.011

比较个性化钛网与传统钛网在引导骨再生后暴露的系统综述

周立波^1,2, 宿玉成^3,4, 李昕茹^1,2, 张立强⁵, 陈德平⁶

¹佳木斯大学附属口腔医院 154000;
²黑龙江省口腔生物医学材料及临床应用重点实验室口腔医学工程实验中心 154000;
³北京口腔种植培训中心 100032;
⁴中国医学科学院北京协和医院 100032;
⁵迪迈仕（北京）科技有限责任公司 101312;
⁶北京瑞城口腔医院 100032

收稿日期:2021-12-13 出版日期:2022-04-30 发布日期:2022-05-07
通讯作者: 张立强,Email：kevin.zhang@dprmat.com,电话：010-50927071;陈德平,Email：studyclub3@163.com,电话：010-66212299
作者简介:周立波,副主任医师、在读博士,研究方向：口腔种植方向研究;张立强,硕士、总经理,研究方向：材料科学与工程专业方向研究;陈德平,主治医师,研究方向：口腔颌面外科、口腔种植学及口腔激光临床应用研究
基金资助:
黑龙江省自然科学基金项目（LH2021H108）; 黑龙江省教育厅青年人才创新计划项目（UNPYSCT-2020057）; 佳木斯大学青年创新人才培养计划项目（JMSUQP2020020）

A systematic review comparing the exposure of customized titanium mesh and conventional titanium mesh after guided bone regeneration

Zhou Libo^1,2, Su Yucheng^3,4, Li Xinru^1,2, Zhang Liqiang⁵, Chen Deping⁶

¹Affiliated stomatological hospital, Jiamusi University, Jiamusi 154000, Heilongjiang, China;
²Heilongjiang Key Lab of Oral Biomedicine Materials and Clinical Application, Heilongjiang Jiamusi, Experimental Center for Stomatological Engineering, Heilongjiang154000, China;
³Beijing Implant Training College,Beijing 100032, China;
⁴Dental Implant Center, Peking Union Medical College Hospital,Chinese Academy Of Medical Sciences, Beijing 100032, China;
⁵Digital Mesh Beijing Technology Co.,LtD, Shunyi, Beijing 101312, China;
⁶Beijing Citident Hospital of Stomatology, Beijing 100032, China

Received:2021-12-13 Online:2022-04-30 Published:2022-05-07
Contact: Zhang Liqiang, Email: kevin.zhang@dprmat.com, Tel: 0086-10-50927071; Chen Deping, Email: studyclub3@163.com, Tel: 0086-10-66212299
Supported by:
Natual Science Foundation of Heilongjiang Province（LH2021H108）; Heilongjiang Provincial Education Department Young Talent Innovation Program Project（UNPYSCT-2020057）; Jiamusi University Young Innovative Talent Training Support Program Project（JMSUQP2020020）

摘要/Abstract

摘要： 目的探讨个性化钛网和传统钛网在引导骨再生(guided bone regeneration,GBR)后暴露率以及软组织裂开发生的时间点,为GBR提供临床参考。方法由2名独立研究员通过计算机检索PubMed、EMbase、Web of Science和Cochrane 4个数据库所有公开发表的有关GBR术后钛网暴露的文章。本研究选取2011年1月1日至2021年12月31日发表的英文文章。应用Stata16.0对最终符合纳入标准的研究数据进行系统分析。结果共找到962篇文章,对其中9篇进行了定量分析。钛网总暴露率的组合值为0.37（95%CI=0.31~0.42）。亚组分析结果显示,个性化钛网暴露率的组合值为0.20（95%CI=0.13~0.27）,传统钛网暴露率的组合值为0.60（95%CI=0.52~0.68）。结论个性化钛网的暴露率低于传统钛网,对GBR精确骨增量提供足够植入空间具有重要意义。

关键词: 钛网, 计算机辅助设计, 3D打印, 骨增量, 暴露

Abstract: Objective To explore the exposure rate of customized titanium mesh and traditional titanium mesh after guided bone regeneration(GBR) and the time point of soft tissue dehiscence, and to provide clinical reference for GBR. Methods Databases, including PubMed, EMbase, Web of Science and Cochrane Central Register Controlled Trials, were searched by two independent researchers, for published articles on titanium mesh exposure after GBR. This study selected English articles published from January 1st, 2011 to December 31th, 2021. Stata 16.0 software was used to systematically analyze the research data that finally met the inclusion criteria. Results A total of 962 articles were found, and 9 of which were quantitatively analysed. The combined value of the total exposure rate of titanium mesh was 0.37（95%CI=0.31~0.42）. The result of subgroup analysis showed that the combined value of the customized titanium mesh exposure rate was 0.20（95%CI=0.13~0.27） and the combined value of the traditional titanium mesh exposure rate was 0.60（95%CI=0.52~0.68）. Conclusion The exposure rate of customized titanium mesh is lower than that of traditional titanium mesh, which is of great significance to provide sufficient grafting space for accurate bone reconstruction in GBR.

Key words: Titanium mesh, Computer-aided design, Three-dimensional printing, Bone regeneration, Exposure

周立波,宿玉成,李昕茹,等. 比较个性化钛网与传统钛网在引导骨再生后暴露的系统综述[J]. 中国口腔种植学杂志, 2022, 27(2): 112-118. DOI: 10.12337/zgkqzzxzz.2022.04.011

Zhou Libo, Su Yucheng, Li Xinru, Zhang Liqiang, Chen Deping. A systematic review comparing the exposure of customized titanium mesh and conventional titanium mesh after guided bone regeneration[J].Chinese Journal of Oral Implantology, 2022, 27(2): 112-118.DOI: 10.12337/zgkqzzxzz.2022.04.011.

参考文献

[1] Bassir SH, Alhareky M, Wangsrimongkol B, et al.Systematic review and meta-analysis of hard tissue outcomes of alveolar ridge preservation[J]. Int J Oral Maxillofac Implants, 2018,33(5):979-994. DOI: 10.11607/jomi.6399.
[2] Hansson S, Halldin A.Alveolar ridge resorption after tooth extraction: a consequence of a fundamental principle of bone physiology[J]. J Dent Biomech, 2012,3:1758736012456543. DOI: 10.1177/1758736012456543.
[3] Buser D, Ingimarsson S, Dula K, et al.Long-term stability of osseointegrated implants in augmented bone: a 5-year prospective study in partially edentulous patients[J]. Int J Periodontics Restorative Dent, 2002,22(2):109-117.
[4] Miyamoto I, Funaki K, Yamauchi K, et al.Alveolar ridge reconstruction with titanium mesh and autogenous particulate bone graft: computed tomography-based evaluations of augmented bone quality and quantity[J]. Clin Implant Dent Relat Res, 2012,14(2):304-311. DOI: 10.1111/j.1708-8208.2009.00257.x.
[5] Briguglio F, Falcomatà D, Marconcini S, et al.The use of titanium mesh in guided bone regeneration: a systematic review[J]. Int J Dent, 2019,2019:9065423. DOI: 10.1155/2019/9065423.
[6] Dahlin C, Linde A, Gottlow J, et al.Healing of bone defects by guided tissue regeneration[J]. Plast Reconstr Surg, 1988,81(5):672-676. DOI: 10.1097/00006534-198805000-00004.
[7] Wang HL, Boyapati L."Pass" principles for predictable bone regeneration[J]. Implant Dent, 2006,15(1):8-17. DOI: 10.1097/01.id.0000204762.39826.0f.
[8] Rasia-dal Polo M, Poli PP, Rancitelli D, et al. Alveolar ridge reconstruction with titanium meshes: a systematic review of the literature[J]. Med Oral Patol Oral Cir Bucal, 2014,19(6):e639-646. DOI: 10.4317/medoral.19998.
[9] Hasegawa H, Kaneko T, Kanno C, et al.Evaluation of a newly designed microperforated titanium membrane with beta-tricalcium phosphate for guided bone regeneration in dog mandibles[J]. Int J Oral Maxillofac Implants, 2019,34(5):1132-1142. DOI: 10.11607/jomi.6776.
[10] Xie Y, Li S, Zhang T, et al.Titanium mesh for bone augmentation in oral implantology: current application and progress[J]. Int J Oral Sci, 2020,12(1):37. DOI: 10.1038/s41368-020-00107-z.
[11] Lizio G, Corinaldesi G, Marchetti C.Alveolar ridge reconstruction with titanium mesh: a three-dimensional evaluation of factors affecting bone augmentation[J]. Int J Oral Maxillofac Implants, 2014,29(6):1354-1363. DOI: 10.11607/jomi.3417.
[12] Sagheb K, Schiegnitz E, Moergel M, et al.Clinical outcome of alveolar ridge augmentation with individualized cad-cam-produced titanium mesh[J]. Int J Implant Dent, 2017,3(1):36. DOI: 10.1186/s40729-017-0097-z.
[13] Lizio G, Mazzone N, Corinaldesi G, et al.Reconstruction of extended and morphologically varied alveolar ridge defects with the titanium mesh technique: clinical and dental implants outcomes[J]. Int J Periodontics Restorative Dent, 2016,36(5):689-697. DOI: 10.11607/prd.2447.
[14] El Chaar E, Urtula AB, Georgantza A, et al.Treatment of atrophic ridges with titanium mesh: a retrospective study using 100% mineralized allograft and comparing dental stone versus 3d-printed models[J]. Int J Periodontics Restorative Dent, 2019,39(4):491-500. DOI: 10.11607/prd.3733.
[15] Pellegrino G, Lizio G, Corinaldesi G, et al.Titanium mesh technique in rehabilitation of totally edentulous atrophic maxillae: a retrospective case series[J]. J Periodontol, 2016,87(5):519-528. DOI: 10.1902/jop.2016.150432.
[16] Hartmann A, Seiler M.Minimizing risk of customized titanium mesh exposures - a retrospective analysis[J]. BMC Oral Health, 2020,20(1):36. DOI: 10.1186/s12903-020-1023-y.
[17] Sumida T, Otawa N, Kamata YU, et al.Custom-made titanium devices as membranes for bone augmentation in implant treatment: clinical application and the comparison with conventional titanium mesh[J]. J Craniomaxillofac Surg, 2015,43(10):2183-2188. DOI: 10.1016/j.jcms.2015.10.020.
[18] Dellavia C, Canciani E, Pellegrini G, et al.Histological assessment of mandibular bone tissue after guided bone regeneration with customized computer-aided design/computer-assisted manufacture titanium mesh in humans: a cohort study[J]. Clin Implant Dent Relat Res, 2021,23(4):600-611. DOI: 10.1111/cid.13025.
[19] Li L, Wang C, Li X, et al.Research on the dimensional accuracy of customized bone augmentation combined with 3d-printing individualized titanium mesh: a retrospective case series study[J]. Clin Implant Dent Relat Res, 2021,23(1):5-18. DOI: 10.1111/cid.12966.
[20] Ricci L, Perrotti V, Ravera L, et al.Rehabilitation of deficient alveolar ridges using titanium grids before and simultaneously with implant placement: a systematic review[J]. J Periodontol, 2013,84(9):1234-1242. DOI: 10.1902/jop.2012.120314.
[21] Ciocca L, Lizio G, Baldissara P, et al.Prosthetically cad-cam-guided bone augmentation of atrophic jaws using customized titanium mesh: preliminary results of an open prospective study[J]. J Oral Implantol, 2018,44(2):131-137. DOI: 10.1563/aaid-joi-D-17-00125.
[22] Kim YK, Yun PY.Risk factors for wound dehiscence after guided bone regeneration in dental implant surgery[J]. Maxillofac Plast Reconstr Surg, 2014,36(3):116-123. DOI: 10.14402/jkamprs.2014.36.3.116.
[23] Lim G, Lin GH, Monje A, et al.Wound healing complications following guided bone regeneration for ridge augmentation: a systematic review and meta-analysis[J]. Int J Oral Maxillofac Implants, 2018,33(1):41-50. DOI: 10.11607/jomi.5581.
[24] Chan HL, Benavides E, Tsai CY, et al.A titanium mesh and particulate allograft for vertical ridge augmentation in the posterior mandible: a pilot study[J]. Int J Periodontics Restorative Dent, 2015,35(4):515-522. DOI: 10.11607/prd.1980.
[25] Lee WZ, Ong M, Yeo AB.Gingival profiles in a select asian cohort: a pilot study[J]. J Investig Clin Dent, 2018,9(1):e12269. DOI: 10.1111/jicd.12269.
[26] Dao H Jr, Kazin RA.Gender differences in skin: a review of the literature[J]. Gend Med, 2007,4(4):308-328. DOI: 10.1016/s1550-8579(07)80061-1.
[27] Hartmann A, Hildebrandt H, Schmohl JU, et al.Evaluation of risk parameters in bone regeneration using a customized titanium mesh: results of a clinical study[J]. Implant Dent, 2019,28(6):543-550. DOI: 10.1097/ID.0000000000000933.
[28] De Freitas RM, Susin C, Spin-Neto R, et al.Horizontal ridge augmentation of the atrophic anterior maxilla using rhbmp-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical trial[J]. J Clin Periodontol, 2013,40(10):968-975. DOI: 10.1111/jcpe.12148.
[29] Stamp R, Fox P, O'Neill W, et al. The development of a scanning strategy for the manufacture of porous biomaterials by selective laser melting[J]. J Mater Sci Mater Med, 2009,20(9):1839-1848. DOI: 10.1007/s10856-009-3763-8.
[30] Aerts E, Li J, Van Steenbergen MJ, et al.Porous titanium fiber mesh with tailored elasticity and its effect on stromal cells[J]. J Biomed Mater Res B Appl Biomater, 2020,108(5):2180-2191. DOI: 10.1002/jbm.b.34556.
[31] Man K, Brunet MY, Louth S, et al.Development of a bone-mimetic 3D printed ti6al4V scaffold to enhance osteoblast-derived extracellular Vesicles' therapeutic efficacy for bone regeneration[J]. Front Bioeng Biotechnol, 2021,9:757220. DOI: 10.3389/fbioe.2021.757220.

比较个性化钛网与传统钛网在引导骨再生后暴露的系统综述

A systematic review comparing the exposure of customized titanium mesh and conventional titanium mesh after guided bone regeneration

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

[1]	周延民, 秦秋月. 上颌窦三维成骨模式促进上颌窦内成骨的临床意义[J]. 中国口腔种植学杂志, 2023, 28(2): 69-76.
[2]	李效宇, 何捷, 王雪珂, 段静旖, 葛畅, 孟维艳. 应用骨胶原结合帐篷技术行上颌后牙连续缺失垂直骨增量一例[J]. 中国口腔种植学杂志, 2023, 28(2): 97-101.
[3]	程熠, 黄海涛. 牙槽骨增量中3D打印个性化支架材料的研究现状[J]. 中国口腔种植学杂志, 2023, 28(2): 114-118.
[4]	中华口腔医学会口腔种植专业委员会. 上颌窦底提升骨增量材料的专家共识：骨代用品[J]. 中国口腔种植学杂志, 2023, 28(1): 3-8.
[5]	周延民, 朱悦萌. 上颌窦三维成骨模式构建[J]. 中国口腔种植学杂志, 2023, 28(1): 9-18.
[6]	中华口腔医学会口腔种植专业委员会. 上颌窦底提升中骨增量材料的专家共识：生物活性制剂、细胞疗法与不植入骨增量材料的上颌窦底提升[J]. 中国口腔种植学杂志, 2022, 27(6): 329-333.
[7]	季平. 3D打印个性化钛网用于复杂骨缺损增量治疗的研究进展[J]. 中国口腔种植学杂志, 2022, 27(6): 334-339.
[8]	中华口腔医学会口腔种植专业委员会. 上颌窦底提升中骨增量材料的专家共识：自体骨[J]. 中国口腔种植学杂志, 2022, 27(5): 269-273.
[9]	李晋蒙, 李笑班, 张健. 复杂牙槽骨缺损临床解决方案的探索与思考[J]. 中国口腔种植学杂志, 2022, 27(5): 285-291.
[10]	皮雪敏, 刘倩, 陈德平, 任斌, 潘红, 宿玉成. 上颌窦底提升方案的决策原则（一）[J]. 中国口腔种植学杂志, 2022, 27(5): 322-326.
[11]	王婷婷, 王凤, 吴轶群. 3D打印数字化个性化钛网在牙槽嵴引导骨再生中的临床应用[J]. 中国口腔种植学杂志, 2022, 27(4): 208-216.
[12]	杨德钊, 许滢洁, 汤正婷, 马玉霄, 李光成, 孟凡文. 拉力螺钉技术在牙槽嵴块状骨移植中的应用[J]. 中国口腔种植学杂志, 2022, 27(4): 217-223.
[13]	庞莉苹, 钟心兰, 王伟岸, 李水根. 采用胶原膜固定法引导骨再生技术行牙槽嵴水平增量的临床试验研究[J]. 中国口腔种植学杂志, 2022, 27(4): 224-228.
[14]	邓磊, 程熠, 赵楠, 陈岗, 黄海涛. 胶原蛋白海绵在穿牙槽嵴上颌窦底提升中应用效果的研究[J]. 中国口腔种植学杂志, 2022, 27(3): 147-155.
[15]	王美洁, 邓悦. 前牙区GBR后种植体唇侧颈部骨增量材料吸收及原因分析[J]. 中国口腔种植学杂志, 2022, 27(3): 156-160.