Abstract: Objective: To analyze the clinical application value of platelet-rich fibrin(PRF)combined with artificial bone meal in oral implant guided bone regeneration. Methods: Oral implant guided bone regeneration patients were taken as the main object of this study. The total number of patients (selected number) was 60. The patients were collected from March 2019 to May 2020. The 60 patients were randomly divided into two groups by computer. Among them, 30 patients were taken as observation group (treated with platelet-rich fibrin combined with artificial bone meal) and 30 patients were taken as control group (treated with biomembrane intervention). The total effective rate, bone graft height, bone formation height and complication rate of the two groups were compared. Results: The total effective rate of the observation group was 90.00% higher than that of the control group 70.00%(P<0.05). The bone graft height (2.67±0.49)mm and bone formation height (2.57±0.39)mm in the observation group were different from those in the control group(P<0.05). The incidence of complications in the observation group was 1.00% lower than that in the control group(10.00%)(P<0.05). Conclusion: The application of platelet-rich fibrin combined with artificial bone meal in the treatment of patients with oral implant-induced bone regeneration has achieved remarkable results, which can promote the regeneration of bone defects and facilitate the early recovery of patients.

Key words: platelet-rich fibrin, artificial bone meal, oral implant guided bone regeneration, clinical application value