Clinical applications of autologous platelet-rich concentrate in keratinized mucosal augmentation

doi:10.12337/zgkqzzxzz.2023.08.008

Abstract

Abstract: Objective s To evaluate the clinical efficacy of the "open suture" combined with platelet-rich fibrin (PRF) in keratinized mucosal augmentation. Methods 84 patients with dentition defects accompanied by keratinized mucosal loss were enrolled in this study, receiving "open suture" combined with PRF after the implant surgery. CBCT was taken before and 3 months after surgery, and oral scanning was performed to record and measure the width of the keratinized mucosa. At the same time, patients were followed up to record the occurrence of postoperative complications and pain levels. Results Compared the preoperative period with 3 months postoperatively, the width of keratinized mucosa increased by（2.81±1.12）mm (P<0.05), while the gingival index (GI) and modified bleeding index (mBI) decreased by 0.85 ± 0.76 (P<0.05) and 0.58 ± 0.28 (P>0.05), respectively. There was no significant difference in the vestibular depth (VD) between these two-time points (P>0.05). Meanwhile, the risk of postoperative complications was low, and the patients' own pain was relatively mild. The VAS score for the first week after surgery is 1.58±0.43. Conclusion This flapless tension-releasing suture technique in combination with the PRF "open suture" could maintain blood supply at the bone-periosteum interface, and preserve the three-dimensional structure of the hard and soft tissues around the initial defect. Also, this suture method could achieve coordination and stability of soft and hard tissues and reduce the risk of complications such as wound dehiscence and mucosal perforation. In addition, without the need for periosteal elevation or free gingival grafts, minimally invasive intervention can promote the growth of soft and hard tissues, reduce the risk of postoperative infection in patients, and promote wound healing, thereby shortening the treatment cycle of patients and improving their postoperative comfort. This can become a predictable method of wound closure.

Key words: Platelet-rich fibrin, Keratinized mucosa, Soft tissue augmentation, Dental implant, Open suture

Zhu Yuemeng, Jia Kewen, Jiao Junjie, Chen Siyu, Ren Sicong, Chen Sheng, Zhou Yanmin. Clinical applications of autologous platelet-rich concentrate in keratinized mucosal augmentation[J]. Chinese Journal of Oral Implantology, 2023, 28(4): 250-259.

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