Abstract: An adequate width of peri-implant keratinized mucosa is crucial for reducing plaque accumulation, decreasing the incidence of peri-implant mucositis, and maintaining long-term implant health. Although various materials are currently available to widen the peri-implant keratinized mucosa, autografts are associated with considerable surgical trauma, whereas artificial substitutes are often limited by high costs. Plasmatrix,a centrifuged autologous blood product rich in growth factors and scaffold-like structures, offers advantages such as excellent biocompatibility, minimal donor-site morbidity, abundant availability, and low cost. Its application for peri-implant keratinized mucosa augmentation may help overcome the limitations of existing materials. Based on current evidence, this article presents the preparation protocol for plasmatrix and clinical experiences with its use in peri-implant keratinized mucosa augmentation, thereby providing practical guidance for clinicians.

Key words: Plasmatrix, Peri-implant keratinized mucosa, Keratinized mucosa width augmentation