Chinese Journal of Oral Implantology ›› 2023, Vol. 28 ›› Issue (1): 35-39.DOI: 10.12337/zgkqzzxzz.2023.02.007

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Characterization of peri-implant microbes and their changes under diseased conditions

Liu Yue, Zhao Yajun, Liu Jin, Du Mi, Lan Jing   

  1. Department of Implantology, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan 250012, China
  • Received:2022-11-13 Online:2023-02-28 Published:2023-03-07
  • Contact: Lan Jing, Email: kqlj@sdu.edu.cn, Tel: 0086-531-88382595
  • Supported by:
    National Natural Science Foundation of China (82100977); China Postdoctoral Science Foundation (2021M691930); The Youth Scientific Research Funds of School of Stomatology, Shandong University (2020QNJJ03)

Abstract: Peri-implant disease is a biological complication that occurs in the peri-implant tissue with plaque biofilm as the initiating factor. The initial colonization, homeostasis, and dysbiosis of peri-implant submucosal microbes are closely related to the healthy and diseased states of the peri-implant. This article reviews the research on the characterization of peri-implant microbes and their changes in the diseased states. The results showed that there are significant differences in the structure of submucosal microbes between states of healthy peri-implant, peri-implant mucositis and peri-implantitis. The count of submucosal periodontal pathogens and the complexity of microbes increased when peri-implant disease occurred. The clinical manifestations of peri-implant disease were correlated with the variety in the type and quantity of microbes.

Key words: Peri-implant disease, Plaque biofilm, Microbe