Short-term observation of 3D-printing individualized titanium mesh in restoration of severe alveolar bone defeats

doi:10.12337/zgkqzzxzz.2021.12.006

Abstract

Abstract: Objective To investigate the short-term clinical effect of 3D-PITM in the restoration of severe alveolar bone defects. Methods Retrospective analysis of 15 objects who underwent the restoration of alveolar bone defeat by utilization of 3D-printing individualized titanium mesh (3D-PITM) combined with guided bone regeneration (GBR) in the Department of dental implantology of Affiliated Stomatology Hospital of Guangzhou Medical University since December 2020. Postoperative infection, 3D-PITM exposure, and patient satisfaction were evaluated and short-term bone augmentation was measured by digital technique. Results A total of 15 patients was included in the current study, none of them had a postoperative infection, only one of them had 3D-PITM exposure (6.0%). Patient satisfaction on the surgery process, postoperative reaction, and follow-up was evaluated to be 8.32±0.79. In 3 months, the average acquired horizontal bone augmentation was (3.02±1.52) mm (maximum at 7.53 mm), and average acquired vertical bone augmentation was (3.71±1.82) mm (maximum at 7.30 mm). Conclusion Utilization of 3D-PITM in the restoration of severe alveolar bone defeat was promising in short-term observations with low infection and exposure rate, and high patient satisfaction outcomes. However, long-term study on bone stability by 3D-PITM is also required.

Key words: 3D-printing individualized titanium mesh, Bone defect, Bone guided regeneration, Restoration guided, Precise restoration

Guo Xueqi, Chen Yunxin, Yang Lan, Chen Xili, Chen Zhongren, Su Hanfu, Wang Liping. Short-term observation of 3D-printing individualized titanium mesh in restoration of severe alveolar bone defeats[J]. Chinese Journal of Oral Implantology, 2021, 26(6): 368-375.

References

[1] Khojasteh A, Kheiri L, Motamedian SR, et al.Guided bone regeneration for the reconstruction of alveolar bone defects[J]. Ann Maxillofac Surg, 2017,7(2):263-277. DOI: 10.4103/ams.ams_76_17.
[2] Chiapasco M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry[J]. Int J Oral Maxilofac Implants,2009,24 Suppl:237-259.
[3] Ciocca L, Lizio G, Baldissara P, et al.Prosthetically CAD-CAM-guided bone augmentation of atrophic jaws using customized titanium mesh: preliminary results of an open prospective study[J]. J Oral Implantol, 2018,44(2):131-137. DOI: 10.1563/aaid-joi-D-17-00125.
[4] Inoue K, Nakajima Y, Omori M, et al.Reconstruction of the alveolar bone using bone augmentation with selective laser melting titanium mesh sheet: a report of 2 cases[J]. Implant Dent, 2018,27(5):602-607. DOI: 10.1097/ID.0000000000000822.
[5] Otawa N, Sumida T, Kitagaki H, et al.Custom-made titanium devices as membranes for bone augmentation in implant treatment: modeling accuracy of titanium products constructed with selective laser melting[J]. J Craniomaxillofac Surg, 2015,43(7):1289-1295. DOI: 10.1016/j.jcms.2015.05.006.
[6] Boyne PJ.Restoration of osseous defects in maxillofacial casualties[J]. J Am Dent Assoc, 1969,78(4):767-776. DOI: 10.1016/s0002-8177(69)84023-7.
[7] Lee SH, Moon JH, Jeong CM, et al.The mechanical properties and biometrical effect of 3D preformed titanium membrane for guided bone regeneration on alveolar bone defect[J]. Biomed Res Int, 2017,2017:7102123. DOI: 10.1155/2017/7102123.
[8] 白丽云, 季平, 李显, 等. 不同厚度的3D打印个性化钛网的三维有限元分析[J].口腔医学研究,2019,35(1):75-79. DOI: 10.13701/j.cnki.kqyxyj.2019.01.018.
[9] Xie Y, Li S, Zhang T, et al.Titanium mesh for bone augmentation in oral implantology: current application and progress[J]. Int J Oral Sci, 2020,12(1):37. DOI: 10.1038/s41368-020-00107-z.
[10] Maryam T, Sorousheh S, Wang L, et al.Intrinsic osteoinductivity of porous titanium scaffold for bone tissue engineering[J]. International Journal of Biomaterials, 2017, 2017:5093063. DOI: 10.1155/2017/5093063.
[11] Gao Hui,Li Xian,Wang Chunjuan et al. Mechanobiologically optimization of a 3D titanium-mesh implant for mandibular large defect: a simulated study[J] .Mater Sci Eng C Mater Biol Appl, 2019, 104: 109934. DOI:10.1016/j.msec.2019.109934.
[12] Bai L, Ji P, Li X, et al.Mechanical characterization of 3D-printed individualized Ti-mesh (membrane) for alveolar bone defects[J]. J Healthc Eng, 2019,2019: 4231872.DOI: 10.1155/2019/4231872.
[13] Li L, Wang C, Li X, et al.Research on the dimensional accuracy of customized bone augmentation combined with 3D-printing individualized titanium mesh: a retrospective case series study[J]. Clin Implant Dent Relat Res, 2021,23(1):5-18. DOI: 10.1111/cid.12966.
[14] 李林芝, 陈丹, 黄元丁, 等. 三维打印个性化钛网联合引导骨再生术修复牙槽骨缺损的临床初探[J].中华口腔医学杂志,2019,54(9):623-627. DOI: 10.3760/cma.j.issn.1002-0098.2019.09.008.
[15] Hartmann A, Seiler M.Minimizing risk of customized titanium mesh exposures - a retrospective analysis[J]. BMC Oral Health, 2020,20(1):36. DOI: 10.1186/s12903-020-1023-y.
[16] Cucchi A, Bianchi A, Calamai P, et al.Clinical and volumetric outcomes after vertical ridge augmentation using computer-aided-design/computer-aided manufacturing (CAD/CAM) customized titanium meshes: a pilot study[J]. BMC Oral Health, 2020,20(1):219. DOI: 10.1186/s12903-020-01205-4.
[17] Urban IA, Montero E, Monje A, et al.Effectiveness of vertical ridge augmentation interventions: a systematic review and meta-analysis[J]. Clin Periodontol. 2019,21:319-339. DOI: 10.1111/jcpe.13061.
[18] Chiapasco M, Casentini P, Tommasato G, et al.Customized CAD/CAM titanium meshes for the guided bone regeneration of severe alveolar ridge defects: preliminary results of a retrospective clinical study in humans[J]. Clin Oral Implants Res, 2021,32(4):498-510. DOI: 10.1111/clr.13720.