种植体周微生物特点及其在疾病状态下的变化

doi:10.12337/zgkqzzxzz.2023.02.007

中国口腔种植学杂志 ›› 2023, Vol. 28 ›› Issue (1): 35-39.DOI: 10.12337/zgkqzzxzz.2023.02.007

种植体周微生物特点及其在疾病状态下的变化

刘月, 赵雅君, 刘金, 杜密, 兰晶

山东大学齐鲁医学院口腔医学院·口腔医院种植科山东省口腔组织再生重点实验室山东省口腔生物材料与组织再生工程实验室山东省口腔疾病临床医学研究中心,济南 250012

收稿日期:2022-11-13 出版日期:2023-02-28 发布日期:2023-03-07
通讯作者: 兰晶,Email：kqlj@sdu.edu.cn,电话：0531-88382595
作者简介:刘月,口腔医学专业型硕士研究生,研究方向：口腔种植学相关研究;兰晶,主任医师、口腔医学博士,研究方向：口腔种植外科和修复相关研究,擅长骨增量、种植美学、无牙颌和数字化种植修复。
基金资助:
国家自然科学基金青年项目（82100977）; 中国博士后科学基金第69批面上资助（2021M691930）; 山东大学口腔医院青年科研基金项目（2020QNJJ03）

Characterization of peri-implant microbes and their changes under diseased conditions

Liu Yue, Zhao Yajun, Liu Jin, Du Mi, Lan Jing

Department of Implantology, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan 250012, China

Received:2022-11-13 Online:2023-02-28 Published:2023-03-07
Contact: Lan Jing, Email: kqlj@sdu.edu.cn, Tel: 0086-531-88382595
Supported by:
National Natural Science Foundation of China (82100977); China Postdoctoral Science Foundation (2021M691930); The Youth Scientific Research Funds of School of Stomatology, Shandong University (2020QNJJ03)

摘要/Abstract

摘要： 种植体周病是以菌斑生物膜为始动因子,发生于种植体周组织的生物学并发症,种植体周黏膜下微生物的初期定植、稳态平衡和紊乱失调与种植体周的健康和疾病状态密切相关。本文综述了种植体周微生物的特点及其在疾病状态下的变化方面的研究情况,结果可以明确种植体周健康、种植体周黏膜炎和种植体周炎状态下的微生物结构存在明显差异。发生种植体周病时,种植体周黏膜下的牙周致病菌的数量增加,微生物的复杂程度增加,并且种植体周病的临床表现与微生物的种类和数量的变化存在相关性。

关键词: 种植体周病, 菌斑生物膜, 微生物

Abstract: Peri-implant disease is a biological complication that occurs in the peri-implant tissue with plaque biofilm as the initiating factor. The initial colonization, homeostasis, and dysbiosis of peri-implant submucosal microbes are closely related to the healthy and diseased states of the peri-implant. This article reviews the research on the characterization of peri-implant microbes and their changes in the diseased states. The results showed that there are significant differences in the structure of submucosal microbes between states of healthy peri-implant, peri-implant mucositis and peri-implantitis. The count of submucosal periodontal pathogens and the complexity of microbes increased when peri-implant disease occurred. The clinical manifestations of peri-implant disease were correlated with the variety in the type and quantity of microbes.

Key words: Peri-implant disease, Plaque biofilm, Microbe

刘月,赵雅君,刘金,等. 种植体周微生物特点及其在疾病状态下的变化[J]. 中国口腔种植学杂志, 2023, 28(1): 35-39. DOI: 10.12337/zgkqzzxzz.2023.02.007

Liu Yue, Zhao Yajun, Liu Jin, Du Mi, Lan Jing. Characterization of peri-implant microbes and their changes under diseased conditions[J].Chinese Journal of Oral Implantology, 2023, 28(1): 35-39.DOI: 10.12337/zgkqzzxzz.2023.02.007.

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种植体周微生物特点及其在疾病状态下的变化

Characterization of peri-implant microbes and their changes under diseased conditions

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