黏性骨在骨再生中的应用研究

doi:10.12337/zgkqzzxzz.2025.04.004

摘要/Abstract

摘要： 血小板中含有大量生长因子,已证明能在再生过程中促进细胞迁移、增殖及血管生成。不少学者将其与骨增量材料混合制成“黏性骨”,便于医生操作。自体骨和同种异体骨移植分别存在取材部位及生物相容性的局限。合成骨增量材料作为另一种骨增量选择,有良好的生物相容性,生长因子和这些多孔骨增量材料联合可以刺激细胞生长及分化,发挥成骨作用。本文依据国内外临床研究数据,综述黏性骨在骨再生中的研究进展,阐述其制作方法及特点,证明其在骨缺损再生方面的良好前景和优势。

关键词: 黏性骨, 血浆制品, 骨再生, 口腔种植

Abstract: The high concentrations of growth factors within platelets have been proven to promote cell migration, proliferation, and angiogenesis during the regeneration process. Multiple efforts have been exerted to blend them with bone substitute materials, to fabricate "sticky bone" for easier manipulation by surgeons. While autologous and allogeneic bone grafts are limited by donor site availability and biocompatibility issues, synthetic bone grafts exhibit significant advantages in terms of biocompatibility. The integration of growth factors into these porous synthetic grafts can effectively stimulate cell growth and differentiation, thereby enhancing osteogenic potential. This paper reviews the research and advancements in sticky bone for bone regeneration, elaborating on the fabrication and characterization of sticky bone materials. Moreover, it also highlights the promising outcomes and benefits of sticky bone in bone defect regeneration, substantiated by clinical data from both domestic and international studies.

Key words: Sticky bone, Plasma products, Bone regeneration, Dental implant

梁艺馨,曲哲. 黏性骨在骨再生中的应用研究[J]. 中国口腔种植学杂志, 2025, 30(2): 111-117. DOI: 10.12337/zgkqzzxzz.2025.04.004

Liang Yixin, Qu Zhe. Research on the utilization of sticky bone in bone regeneration[J].Chinese Journal of Oral Implantology, 2025, 30(2): 111-117.DOI: 10.12337/zgkqzzxzz.2025.04.004.

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