关键词: C反应蛋白, 尿脱氧吡啶啉, 肌酐, 口腔种植修复术

Abstract: Objective： To analyze the correlation between C-reactive protein(CRP), urinary deoxypyridine (UD- Pd)/creatinine content (Scr) and inflammatory indicators in patients with oral implantation. Methods： 60 patients who received oral implantation in our hospital were selected as the observation group, and 60 healthy adults were selected as the control group. Serum C reactive protein(CRP), urinary deoxypyridine (UDPd)/creatinine(Sce), interleukin-1 (IL-1), interleukin 6 (IL-6) and tumor necrosis factor were com- pared between the two groups. Results： Serum CRP, IL-1, IL-6, TNF-levels and UDPd/ Scr in the obser- vation group were significantly higher than those in the control group 1 week and 1 month after surgery(P< 0.05), Pearson correlation analysis showed that CRP level in the observation group was positively correlat- ed with UDPd/Scr ratio 1 month after surgery(r=0.301, P=0.004). According to the X-ray examination re- sults, the patients were divided into the poorly integrated group(n=8) and the well-integrated group(n=52). The CRP, UDPd/ Scr ratio and IL-1, IL-6 and TNF-levels in the well-integrated group were significantly lower than those in the poorly integrated group(P<0.05). Conclusion： In the process of oral repair, serum CRP and urine UDPd/Scr ratio will be significantly increased and there is a positive correlation between the two. CRP, UDPd/Scr and other inflammatory indicators are correlated with the prognosis of patients with oral implantation and restoration.

Key words: C-reactive protein, urinary deoxypyridine, creatinine, dental implant repair