Effect of PRF on immediate implant of anterior teeth loss and its effect on bone resorption

doi:10.12337/zgkqzzxzz.2020.06.001

Abstract

Abstract: Objective: To study the effect of PRF on immediate implant of anterior teeth loss and its effect on bone resorption. Methods: Ninety patients with anterior teeth missing admitted to our hospital from May 2017 to May 2019 were selected as the research objects. They were randomly divided into two groups: observation group and control group, 45 cases in each group. The control group was treated routinely after implantation, while the observation group was treated with PRF after extraction. The clinical efficacy, cosmetic effect and adverse reactions were compared between the two groups. Two groups of patients were reexamined after 2, 4, 8 and 12 months of treatment, and bone resorption levels were compared between the two groups at different time points. Results: The effective rate of the observation group was 97.78%, which was significantly higher than that of the control group(82.22%, P<0.05). The bone resorption level of the two groups decreased after 4, 8, 12 months of treatment compared with 2 months of treatment(P<0.05). After 2, 4 and 8 months of treatment, the bone resorption level in the observation group was significantly lower than that in the control group(P<0.05). There was no difference in bone resorption between the two groups after 12 months of treatment(P>0.05). After treatment, there was no difference in tooth color and facial condition score between the observation group and the control group(P>0.05). After treatment, the scores of dental appearance and overall aesthetics in the observation group were significantly higher than those in the control group(P<0.05). After 12 months of treatment, the total incidence of adverse reactions in the observation group was 6.67%, which was significantly lower than that in the control group(24.4%, P<0.05). Conclusion: PRF can promote bone tissue repair and wound healing, reduce bone resorption, reduce the incidence of adverse reactions after treatment, and improve dental aesthetics. It is worthy of clinical promotion.

Key words: PRF, missing anterior teeth, immediate planting, bone resorption

CLC Number:

R782.13

HUANG Bei, TANG Caomin, ZHANG Sheng, et al. Effect of PRF on immediate implant of anterior teeth loss and its effect on bone resorption[J]. Chinese Journal of Oral Implantology, 2020, 25(2): 51-54.

References

1 祝岩, 万澎波, 赵伟, 等. 上颌前牙美学区连续多颗牙缺失即刻种植的临床研究[J]. 口腔医学, 2016, 36(8): 700-705
2 曹建强, 王丽芳, 田碧媛, 等. 上前牙外伤脱落即刻种植美学修复设计的研究[J]. 口腔医学, 2017, 37(6): 528-531
3 张楠楠, 高玉琴, 王洋. 口腔即刻种植即刻修复义齿手术的配合及护理体会[J]. 中国医科大学学报, 2017, 46(1): 91-93
4 白慧子, 木合塔尔·霍加, 王腾, 等. 牙髓干细胞修复即刻种植周围骨缺损[J]. 临床口腔医学杂志, 2016, 32(11): 643-645
5 王翔宇, 刘姒, 吴祥冰. 翻瓣刮治联合引导骨再生术治疗牙种植周围感染的临床研究[J]. 现代中西医结合杂志, 2018, 27(3): 279-281
6 孙晓琳, 周延民, 赵静辉, 等. PRF在前牙即刻种植修复中的应用[J]. 实用口腔医学杂志, 2018,34(1): 125-126
7 黄会杰, 陈贵丰. 口腔种植修复与常规修复治疗牙列缺失的效果比较[J]. 广东医学, 2016, 37(4): 583-584
8 Dohan D M, Choukroun J, Diss A, et al. Platelet-rich fibrin(PRF): A second-generation platelet concentrate. Part I: Technological concepts and evolution[J]. oral surgery oral medicine oral pathology oral radiology & endodontics, 2006, 101(3) : 45-50
9 罗三莲, 童昕, 高太智, 等. 浓缩生长因子复合Bio-Oss骨粉对前牙三壁骨缺损患者种植疗效及新骨形成的影响[J]. 山东医药, 2015,55(33): 8-10
10 Rudolf Fürhauser, Florescu D, Benesch T, et al. Evaluation of soft tissue around single-tooth implant crowns: the Pink Esthetic Score[J]. Clinical Oral Implants Research, 2006, 16(6) : 639-644
11 Laurens, den, Hartog, et al. Single-Tooth Implants with Different Neck Designs: A Randomized Clinical Trial Evaluating the Aesthetic Outcome[J]. Clinical Implant Dentistry & Related Research, 2011,311-321
12 周小彤, 莫显超. 二氧化锆全瓷牙在牙齿美容修复中的效果分析[J]. 中国美容医学, 2019, 28(1) : 138-140
13 周会, 吕林虎, 刘敏. 浓缩生长因子对炎症期即刻种植临床效果影响的研究[J]. 安徽医科大学学报, 2017, 52(8) : 1255-1257
14 李少冰, 倪佳, 张雪洋, 等. 上前牙区即刻种植联合即刻修复唇侧骨壁预后的评估[J]. 中国组织工程研究, 2018, 22(18) : 2855-2859
15 于鑫玮, 高承志. 自体静脉血在不同离心条件下特定生长因子成分测定与分析性研究[J]. 中国医药导刊, 2016, 18(9) : 865-868
16 冯靖, 宋砚斌, 蒋锋,等. PRF联合钛网在前牙美学区牙种植中应用的临床研究[J]. 口腔医学, 2018, 38(11) : 45-48
17 罗雯静, 赵静辉, 马珊珊,等. 富血小板血纤蛋白的生物组成和功能[J]. 国际口腔医学杂志, 2014, 41(4) : 448-454
18 赵静, 李新月. 富血小板纤维蛋白和浓缩生长因子析出液中相关成骨生长因子含量的比较研究[J]. 牙体牙髓牙周病学杂志, 2018, 28(11) : 13-17+33
19 衣红梅, 薛洪权, 吴鸿, 等. 富含血小板纤维蛋白修复即刻种植体周围骨缺损的临床观察[J]. 现代口腔医学杂志, 2018, 32(1) : 20-22
20 廖军, 徐普. 富血小板血纤蛋白在牙槽嵴位点保存中的应用[J]. 国际口腔医学杂志, 2016, 43(2) : 216-219

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