Research progress on medication-related osteonecrosis of the jaw

doi:10.12337/zgkqzzxzz.2024.10.016

Abstract

Abstract: Medication-related osteonecrosis of the jaw (MRONJ) may be induced during the treatment of oral diseases in patients receiving anti-resorptive drugs such as bisphosphonates and denosumab, as well as angiogenesis inhibitors. However, the exact mechanism of MRONJ remains unclear, and although numerous studies have established clinical treatment databases, definitive treatment strategies have yet to be developed. Through a review of the literature, this study discusses the definition, etiology, staging, risk factors, treatment and prevention of MRONJ, providing a reference for clinical practice in oral healthcare.

Key words: Bisphosphonate-related osteonecrosis of the jaw, Medication-related osteonecrosis of the jaw, Bisphosphonates, Denosumab

Gao Tingting, Bao Yongjie, Lv Xiaoyan, Chen Xian, Liu Yang, Xu Yilei, Lu Huanyou. Research progress on medication-related osteonecrosis of the jaw[J]. Chinese Journal of Oral Implantology, 2024, 29(5): 492-497.

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