Effect of CGF and Bio-oss ratio on site preservation

doi:10.12337/zgkqzzxzz.2020.12.001

Abstract

Abstract: Objective: Different ratios of CGF and Bio-oss were filled in teeth extraction socket, to explore the ratio of better site preservation effect. Methods: 24 male New Zealand rabbits, the experiment has been approved by the ethics committee of Hospital of Stomatology Hebei Medical University. Groups A, B and C were CGF mixed with Bio-oss at the ratio of 2:1, 1:1 and 1:2. Group D was control group. The teeth extraction socket of the first premolar on both sides of mandible was filled with the same ratio. The left operation was performed on 8 weeks after the right operation, and then they were sacrificed after 4 weeks.Amount of new bone formation and the degree of bone maturity were observed histologically at 4 and 12 weeks using HE and Masson stain. X-rays were used to evaluate the alveolar bone absorption.All images were analyzed by image-pro Plus6.0. Results: At the same time, the order of was group A, B, C and D(P<0.05), alveolar bone resorption in group A, B and C was smaller than group D(P<0.05). At the same group, the new bone formation, bone mass, alveolar bone resorption at 12 weeks was higher than that at 4 week（P<0.05）. Conclusion: When CGF and Bio-oss were mixed in the ratio of 2:1 was better.

Key words: concentrated growth factor(CGF), Bio-oss, site preservation

CLC Number:

R782.1

LI Beibei, CHEN Zhiyu, YUAN Shuo, et al. Effect of CGF and Bio-oss ratio on site preservation[J]. Chinese Journal of Oral Implantology, 2020, 25(4): 151-154.

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