干燥综合征患者口腔种植修复的风险因素分析与治疗策略

doi:10.12337/zgkqzzxzz.2024.08.005

中国口腔种植学杂志 ›› 2024, Vol. 29 ›› Issue (4): 320-327.DOI: 10.12337/zgkqzzxzz.2024.08.005

• “全身系统性疾病与牙种植”重点栏目 • 上一篇下一篇

干燥综合征患者口腔种植修复的风险因素分析与治疗策略

陈莉¹, 方明¹, 张燕婷¹, 张晓林¹, 刘青², 郑朝辉³, 周炜¹

¹口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心陕西省口腔医学重点实验室,第四军医大学口腔医院修复科,西安 710032;
²口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心陕西省口腔医学重点实验室第四军医大学口腔医院口腔黏膜病科,西安 710032;
³第四军医大学西京医院临床免疫科,西安 710032

收稿日期:2024-05-31 出版日期:2024-08-30 发布日期:2024-08-16
通讯作者: 陈莉,Email：zhouwei0474@sina.com,电话：029-87776128
作者简介:陈莉主治医师,研究方向：前牙美学微创修复与口腔种植修复、骨再生材料研究; 周炜, 博士、副主任医师,研究方向：口腔种植修复、口腔美学和显微修复

Risk factor analysis and treatment strategies for oral implant restoration in patients with Sjögren syndrome

Chen Li¹, Fang Ming¹, Zhang Yanting¹, Zhang Xiaolin¹, Liu Qing², Zheng Zhaohui³, Zhou Wei¹

¹State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi' an 710032, China;
²State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Oral Medicine, School of Stomatology, The Fourth Military Medical University, Xi' an 710032, China;
³Department of Clinical Immunology, Xijing Hospital, The Fourth Military Medical University, Xi' an 710032, China

Received:2024-05-31 Online:2024-08-30 Published:2024-08-16
Contact: Zhou Wei, Email: zhouwei0474@sina.com, Tel: 0086-29-87776128

摘要/Abstract

摘要： 干燥综合征是口腔临床中一类常见疾病,以眼干、口干等为临床典型症状,伴随复杂的全身状况及长期用药史。近年来随着口腔种植修复的普及,该类患者口腔种植修复的需求也明显增加,但国内外尚未见干燥综合征患者口腔种植修复的治疗指南。本文以1例干燥综合征患者行全口种植固定修复为例,总结这类患者口腔种植修复相关治疗经验,讨论干燥综合征患者口腔种植修复的风险评估与治疗策略。完善的风险评估、合理的口腔种植修复方案以及终身的菌斑控制是干燥综合征患者口腔种植修复成功的基础。

关键词: 干燥综合征, 种植修复, 风险因素, 治疗程序

Abstract: Sjögren syndrome (SS) is a common disease in oral clinical practice with typical symptoms such as dry mouth and dry eyes, often accompanied by complex systemic symptoms and a long history of medication. With the growing prevalence of dental implant restorations, there has been a corresponding rise in the demand for implantation treatments among individuals with Sjögren Syndrome. However, there is a lack of relevant treatment guidelines for implant restoration in these patients. This article presents a case of an implant-supported fixed complete dental prosthesis in a patient with Sjögren syndrome,summarizes our team's experience in the treatment of implant restoration in these patients, and discusses the risk assessment and treatment strategies for dental implant restorations in patients with Sjögren syndrome. A comprehensive risk assessment before treatment, a reasonable implant restoration plan, and consistent long-term plaque control are essential for the successful outcomes of implant restorations in patients with Sjögren syndrome.

Key words: Sjögren syndrome, Dental implant, Risk factors, Treatment protocols

陈莉,方明,张燕婷,等. 干燥综合征患者口腔种植修复的风险因素分析与治疗策略[J]. 中国口腔种植学杂志, 2024, 29(4): 320-327. DOI: 10.12337/zgkqzzxzz.2024.08.005

Chen Li, Fang Ming, Zhang Yanting, Zhang Xiaolin, Liu Qing, Zheng Zhaohui, Zhou Wei. Risk factor analysis and treatment strategies for oral implant restoration in patients with Sjögren syndrome[J].Chinese Journal of Oral Implantology, 2024, 29(4): 320-327.DOI: 10.12337/zgkqzzxzz.2024.08.005.

参考文献

[1] Akin R K, Kreller A J, Walters P J, et al.Sjögren's syndrome[J].Plastic Reconstructive Surg, 1975, 56(4):462.
[2] Atkinson JC, Fox PC. Sjögren's syndrome: oral and dental considerations[J]. J Am Dent Assoc, 1993,124(3):74-76, 78-82, 84-86. DOI: 10.14219/jada.archive.1993.0064.
[3] Margaix-Muoz M, José V Bagán, Poveda R,et al.Sjögren's syndrome of the oral cavity. Review and update[J].Med Oral Patol Oral Cir Bucal, 2009, 14(7):e325-e330.
[4] Fox R, Howell F.Oral problems in patients with Sjögren's syndrome[J].Scandinavian journal of rheumatology. Supplement, 1986, 61:194-200. DOI:10.1111/j.1365-3083.2006.01811.x.
[5] Le Gall M, Cornec D, Pers JO, et al.A prospective evaluation of dental and periodontal status in patients with suspected Sjögren's syndrome[J]. Joint Bone Spine, 2016,83(2):235-236. DOI: 10.1016/j.jbspin.2015.02.015.
[6] Tanaka A, Kellesarian SV, Arany S.Xerostomia and patients' satisfaction with removable denture performance: systematic review[J]. Quintessence Int, 2021,52(1):46-55. DOI: 10.3290/j.qi.a45427.
[7] Ginesin O, Mayer Y, Gabay E, et al.Revealing leukocyte populations in human peri-implantitis and periodontitis using flow cytometry[J]. Clin Oral Investig, 2023,27(9):5499-5508. DOI: 10.1007/s00784-023-05168-y.
[8] Jin L, Dai M, Li C, et al.Risk factors for primary Sjögren's syndrome: a systematic review and meta-analysis[J]. Clin Rheumatol, 2023,42(2):327-338. DOI: 10.1007/s10067-022-06474-8.
[9] Donos N, Calciolari E.Dental implants in patients affected by systemic diseases[J]. Br Dent J, 2014,217(8):425-430. DOI: 10.1038/sj.bdj.2014.911.
[10] Ramos-Casals M, Brito-Zerón P, Bombardieri S, et al.EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies[J]. Ann Rheum Dis, 2020,79(1):3-18. DOI: 10.1136/annrheumdis-2019-216114.
[11] 王倩, 戴生明. 《2019年欧洲抗风湿病联盟干燥综合征局部与系统性治疗推荐》解读[J].中华临床免疫和变态反应杂志,2020,14(3):179-182. DOI: 10.3969/j.issn.1673-8705.2020.03.001.
[12] Ramos-Casals M, Brito-Zerón P, Bombardieri S, et al.EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies[J]. Ann Rheum Dis, 2020,79(1):3-18. DOI: 10.1136/annrheumdis-2019-216114.
[13] Furness S, Bryan G, McMillan R, et al. Interventions for the management of dry mouth: non-pharmacological interventions[J]. Cochrane Database Syst Rev, 2013,2013(9):CD009603. DOI: 10.1002/14651858.CD009603.pub3.
[14] Ramos-Casals M, Tzioufas AG, Stone JH, et al.Treatment of primary Sjögren syndrome: a systematic review[J]. JAMA, 2010,304(4):452-460. DOI: 10.1001/jama.2010.1014.
[15] Bornstein MM, Cionca N, Mombelli A.Systemic conditions and treatments as risks for implant therapy[J]. Int J Oral Maxillofac Implants, 2009,24(Suppl):12-27.
[16] Ozen G, Pedro S, Wolfe F, et al.Medications associated with fracture risk in patients with rheumatoid arthritis[J]. Ann Rheum Dis, 2019,78(8):1041-1047. DOI: 10.1136/annrheumdis-2019-215328.
[17] Chochlidakis K, Ercoli C, Elad S.Challenges in implant-supported dental treatment in patients with Sjögren's syndrome: a case report and literature review[J]. Quintessence Int, 2016,47(6):515-524. DOI: 10.3290/j.qi.a36009.
[18] 邢海霞, 王琳, 潘洁, 等. 干燥综合征患者口腔种植修复的临床策略[J].中国口腔医学继续教育杂志,2023, 26(4):240-246. DOI: 10.12337/zgkqjxjyzz. 2023.04.002.
[19] Goodman SM, Springer BD, Chen AF, et al.2022 american college of rheumatology/american association of hip and knee surgeons guideline for the perioperative management of antirheumatic medication in patients with rheumatic diseases undergoing elective total hip or total knee arthroplasty[J]. Arthritis Care Res (Hoboken), 2022,74(9):1399-1408. DOI: 10.1002/acr.24893.
[20] Chrcanovic BR, Kisch J, Wennerberg A.Dental implants in patients with Sjögren's syndrome: a case series and a systematic review[J]. Int J Oral Maxillofac Surg, 2019, 48(9): 1250-1259
[21] 罗翠芬, 彭国光, 冯远华, 等. 干燥综合征患者牙种植1例[J].华西口腔医学杂志,2017,35(1):108-111. DOI: 10.7518/hxkq.2017.01.018.
[22] 孟迅吾,徐苓.骨质疏松症和骨矿盐疾病诊疗指南[C].中国骨质疏松与骨矿盐疾病诊疗指南专题研讨班暨浙江省骨质疏松与骨矿盐疾病防治进展学术年会论文汇编.杭州: 2007.
[23] Duru N, van der Goes MC, Jacobs JW, et al. EULAR evidence-based and consensus-based recommendations on the management of medium to high-dose glucocorticoid therapy in rheumatic diseases[J]. Ann Rheum Dis, 2013,72(12):1905-1913. DOI: 10.1136/annrheumdis-2013-203249.
[24] Korfage A, Raghoebar GM, Arends S, et al.Dental implants in patients with Sjögren's syndrome[J]. Clin Implant Dent Relat Res, 2016,18(5):937-945. DOI: 10.1111/cid.12376.
[25] Chrcanovic BR, Kisch J, Wennerberg A.Dental implants in patients with Sjögren's syndrome: a case series and a systematic review[J]. Int J Oral Maxillofac Surg, 2019,48(9):1250-1259.
[26] Hashimoto H, Hashimoto S, Muto A, et al.Influence of plaque control on the relationship between rheumatoid arthritis and periodontal health status among japanese rheumatoid arthritis patients[J]. J Periodontol, 2018,89(9):1033-1042. DOI: 10.1002/JPER.17-0575.
[27] 风湿免疫病慢病管理全国护理协作组. 干燥综合征护理管理专家共识[J].护理管理杂志,2021,21(4):265-270,275. DOI: 10.3969/j.issn.1671-315x.2021.04.008.

干燥综合征患者口腔种植修复的风险因素分析与治疗策略

Risk factor analysis and treatment strategies for oral implant restoration in patients with Sjögren syndrome

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