中国口腔种植学杂志 ›› 2025, Vol. 30 ›› Issue (5): 472-480.DOI: 10.12337/zgkqzzxzz.2025.10.007

• 临床研究 • 上一篇    下一篇

胶原蛋白海绵修补穿牙槽嵴上颌窦底提升中窦膜穿孔的回顾性研究

厉润旭, 邓磊, 黄海涛   

  1. 大连医科大学附属第一医院口腔科 116011
  • 收稿日期:2025-04-30 出版日期:2025-10-30 发布日期:2025-10-30
  • 通讯作者: 黄海涛,Email:dlykfykq1999@163.com,电话:0411-83635963-3287
  • 作者简介:厉润旭,医师、口腔医学硕士,研究方向:口腔颌面外科和口腔种植;黄海涛,教授、主任医师、硕士研究生导师,研究方向:口腔颌面外科和口腔种植外科
  • 基金资助:
    大医附一——大连化物所医工联合创新基金(DMU-1&DICP UN202210)

Retrospective study on collagen sponge repair of sinus membrane perforation during transcrestal sinus floor elevation

Li Runxu, Deng Lei, Huang Haitao   

  1. Department of Stomatology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning, China
  • Received:2025-04-30 Online:2025-10-30 Published:2025-10-30
  • Contact: Huang Haitao, Email: dlykfykq1999@163.com, Tel: 0086-411-83635963-3287
  • Supported by:
    Medical-Industrial Union Innovation Fund of the First Affiliated Hospital of Dalian Medical University-Dalian Institute of Chemical Physics ( DMU-1&DICP UN202210)

摘要: 目的 评估胶原蛋白海绵修补穿牙槽嵴上颌窦底提升(TSFE)中窦膜穿孔的临床效果。方法 回顾性纳入2019年9月至2024年9月就诊于大连医科大学附属第一医院口腔科行TSFE的30例患者(42颗种植体),按术中是否发生窦膜穿孔分为穿孔组(n=13)与非穿孔组(n=29)。比较术前、术后即刻和术后6个月的锥形束计算机体层成像(CBCT)影像,测量新生骨高度(NBH)及新生骨指数(NBH/IPL)。结果 穿孔率为30.95%;术后6个月2组种植体留存率均为100%,无窦腔感染。穿孔组NBH为(2.22±0.61)mm,NBH/IPL中位数为58.33%(42.08%,84.58%),均低于非穿孔组(P<0.05);穿孔组(A型和C型)成骨与非穿孔组差异无统计学意义(P>0.05),B型穿孔成骨显著减少(P<0.05)。结论 胶原蛋白海绵可部分封闭TSFE窦膜穿孔并维持基础成骨,但穿孔会使成骨量降低,B型穿孔影响最大。

关键词: 穿牙槽嵴上颌窦底提升, 胶原蛋白海绵, 施耐德膜穿孔

Abstract: Objective To evaluate the efficacy of collagen sponges in repairing maxillary sinus membrane perforations in transcrestal sinus floor elevation (TSFE). Methods A total of 30 patients (42 implants) who underwent TSFE in the Department of Stomatology at the First Affiliated Hospital of Dalian Medical University from September 2019 to September 2024 were enrolled in this retrospective analysis. Based on the occurrence of intraoperative perforation, the patients were divided into a perforation group (n=13) and a non-perforation group (n=29). Cone-beam computed tomography (CBCT) images were obtained and analyzed at baseline, immediately after surgery, and 6 months postoperatively to assess new bone height (NBH) and new bone height / implant protrusion length ratio(NBH/IPL). Results The perforation rate was 30.95%. Both groups achieved 100% implant retention at 6 months with no maxillary sinus infection observed. The perforation group exhibited a mean NBH of (2.22±0.61) mm and an NBH/IPL of 58.33% (42.08%, 84.58%), both significantly lower than those of the non-perforation group (P<0.05). Type A and C perforation groups showed no statistically significant difference in bone formation compared to the non-perforation group (P>0.05), while the Type B perforation group exhibited significantly reduced bone formation (P<0.05). Conclusion Collagen sponges can partially seal TSFE sinus membrane perforations and maintain baseline bone formation, but such perforations still reduce bone formation volume.

Key words: Transcrestal sinus floor elevation, Absorbable collagen sponge, Schneiderian membrane perforation