Abstract: Objective: To investigate the relationship between serum CRP（C-Reactive Protein）and urine de-oxypyridinoline in patients with dental implant repair at different stages. Methods: 100 patients who needed artificial implantation of a single tooth in our hospital were selected as the study subjects, and all the patients met the criteria of this study. The patients were performed 1 day before operation and 1 month after operation, respectively. Serum CRP and urine deoxypyridine were measured 6 months after opera-tion. The results were recorded as group A, group B and group C. Results: The level of serum CRP in 1 month after operation was significantly higher than that in the first day of operation, and the serum CRP was significantly decreased at 6 months after operation(P<0.05). Compared with the results of the three groups, the mean of the three groups was statistically different. The comparison of the results of the three groups showed that the serum CRP was significantly increased at 1 month after operation. Results there was a significant difference between the two groups(P<0.05). Although the serum CRP measured 6 months after operation was higher than that of serum CRP measured 1 day before operation, there was no signifi-cant difference between the two groups(P>0.05). The results of 1 day after operation and 6 months after op-eration were higher than those of 1 day before operation, and the highest value was detected in 1 month af-ter operation(P<0.05). There was statistical difference in the mean value between the two groups. The re-sults of pre-operation were statistically different from those of the other two groups(P<0.05), but there was no statistical difference between the two groups after operation(P>0.05). Conclusion: Serum CRP and uri-nary deoxypyridinoline levels increased during the active period of alveolar bone resorption during oral re-pair. Serum CRP and urine deoxypyridinoline can be used as a preliminary index for alveolar bone remod-eling in the period of artificial dental implant repair.

Key words: oral repair, serum C-reactive protein, urine deoxypyridine, content change rule, correlation analysis